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2IMI
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Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
分子名称: Epsilon-class Glutathione S-transferase, GLUTATHIONE
著者Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
登録日2006-10-02
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
2IL3
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Structures of an Insect Epsilon-class Glutathione S-transferase from the Malaria Vector Anopheles Gambiae: Evidence for High DDT-detoxifying Activity
分子名称: Epsilon-class Glutathione S-transferase
著者Wang, Y, Hemingway, J, Ranson, H, Meehan, E.J, Chen, L.
登録日2006-10-02
公開日2007-10-09
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structure of an insect epsilon class glutathione S-transferase from the malaria vector Anopheles gambiae provides an explanation for the high DDT-detoxifying activity
J.Struct.Biol., 164, 2008
2GTU
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LIGAND-FREE HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18), MONOCLINIC CRYSTAL FORM
分子名称: GLUTATHIONE S-TRANSFERASE
著者Patskovska, L.N, Fedorov, A.A, Patskovsky, Y.V, Almo, S.C, Listowsky, I.
登録日1998-05-26
公開日1999-03-02
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献The enhanced affinity for thiolate anion and activation of enzyme-bound glutathione is governed by an arginine residue of human Mu class glutathione S-transferases.
J.Biol.Chem., 275, 2000
2GST
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STRUCTURE OF THE XENOBIOTIC SUBSTRATE BINDING SITE OF A GLUTATHIONE S-TRANSFERASE AS REVEALED BY X-RAY CRYSTALLOGRAPHIC ANALYSIS OF PRODUCT COMPLEXES WITH THE DIASTEREOMERS OF 9-(S-GLUTATHIONYL)-10-HYDROXY-9, 10-DIHYDROPHENANTHRENE
分子名称: GLUTATHIONE S-TRANSFERASE, L-gamma-glutamyl-S-[(9S,10S)-10-hydroxy-9,10-dihydrophenanthren-9-yl]-L-cysteinylglycine, SULFATE ION
著者Ji, X, Armstrong, R.N, Gilliland, G.L.
登録日1993-06-07
公開日1993-10-31
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure and function of the xenobiotic substrate binding site of a glutathione S-transferase as revealed by X-ray crystallographic analysis of product complexes with the diastereomers of 9-(S-glutathionyl)-10-hydroxy-9,10-dihydrophenanthrene.
Biochemistry, 33, 1994
2GDR
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Crystal structure of a bacterial glutathione transferase
分子名称: GLUTATHIONE, glutathione S-transferase
著者Tocheva, E.I, Fortin, P.D, Eltis, L.D, Murphy, M.E.P.
登録日2006-03-16
公開日2006-08-22
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of Ternary Complexes of BphK, a Bacterial Glutathione S-Transferase That Reductively Dechlorinates Polychlorinated Biphenyl Metabolites.
J.Biol.Chem., 281, 2006
2F8F
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BU of 2f8f by Molmil
Crystal structure of the Y10F mutant of the gluathione s-transferase from schistosoma haematobium
分子名称: GLUTATHIONE, Glutathione S-transferase 28 kDa
著者Gourlay, L.J, Baiocco, P, Angelucci, F, Miele, A.E, Bellelli, A, Brunori, M.
登録日2005-12-02
公開日2006-07-04
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Probing the Mechanism of GSH Activation in Schistosoma haematobium Glutathione-S-transferase by Site-directed Mutagenesis and X-ray Crystallography.
J.Mol.Biol., 360, 2006
2F3M
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Structure of human GLUTATHIONE S-TRANSFERASE M1A-1A complexed with 1-(S-(GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXADIENATE ANION
分子名称: 1-(S-GLUTATHIONYL)-2,4,6-TRINITROCYCLOHEXA-2,5-DIENE, Glutathione S-transferase Mu 1
著者Patskovsky, Y, Patskovska, L, Almo, S.C, Listowsky, I.
登録日2005-11-21
公開日2006-04-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry, 45, 2006
2DSA
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Ternary complex of BphK, a bacterial GST
分子名称: (2Z,4E)-2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOIC ACID, GLUTATHIONE, Glutathione S-transferase
著者Tocheva, E.I, Murphy, M.E.P.
登録日2006-06-24
公開日2006-08-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structures of ternary complexes of BphK, a bacterial glutathione S-transferase that reductively dechlorinates polychlorinated biphenyl metabolites
J.Biol.Chem., 281, 2006
2DC5
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Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution
分子名称: Glutathione S-transferase, mu 7
著者Kamo, S, Kishishita, S, Murayama, K, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-12-28
公開日2006-06-28
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Crystal structure of mouse glutathione S-transferase, mu7 (GSTM7) at 1.6 A resolution
To be Published
2CAQ
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Structure of R21L mutant of Sh28GST in complex with GSH
分子名称: BETA-MERCAPTOETHANOL, GLUTATHIONE, GLUTATHIONE S-TRANSFERASE 28 KDA, ...
著者Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Miele, A.E, Brunori, M.
登録日2005-12-22
公開日2006-06-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2CAI
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BU of 2cai by Molmil
Structure of Glutathione-S-Transferase mutant, R21L, from Schistosoma Haematobium
分子名称: BETA-MERCAPTOETHANOL, GLUTATHIONE S-TRANSFERASE 28 KDA, SULFATE ION, ...
著者Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Brunori, M, Miele, A.E.
登録日2005-12-21
公開日2006-06-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.26 Å)
主引用文献Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2CA8
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Structure of Sh28GST in complex with GSH at pH 6.0
分子名称: GLUTATHIONE, GLUTATHIONE S-TRANSFERASE 28 KDA, TETRAETHYLENE GLYCOL
著者Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Miele, A.E, Brunori, M.
登録日2005-12-20
公開日2006-06-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2C8U
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Structure of R21Q mutant of Sh28GST
分子名称: BETA-MERCAPTOETHANOL, GLUTATHIONE S-TRANSFERASE 28 KDA, SULFATE ION
著者Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Miele, A.E, Brunori, M.
登録日2005-12-07
公開日2006-06-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2C80
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Structure of Sh28GST in complex with S-hexyl Glutathione
分子名称: GLUTATHIONE S-TRANSFERASE 28 KDA, S-HEXYLGLUTATHIONE, TETRAETHYLENE GLYCOL
著者Baiocco, P, Gourlay, L.J, Angelucci, F, Bellelli, A, Brunori, M, Miele, A.E.
登録日2005-11-30
公開日2006-06-21
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Probing the Mechanism of Gsh Activation in Schistosoma Haematobium Glutathione-S-Transferase by Site-Directed Mutagenesis and X-Ray Crystallography.
J.Mol.Biol., 360, 2006
2C4J
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Human glutathione-S-transferase M2-2 T210S mutant in complex with glutathione-styrene oxide conjugate
分子名称: GLUTATHIONE S-TRANSFERASE MU 2, L-GAMMA-GLUTAMYL-S-[(2S)-2-HYDROXY-2-PHENYLETHYL]-L-CYSTEINYLGLYCINE
著者Tars, K, Andersson, M, Ivarsson, Y, Olin, B, Mannervik, B.
登録日2005-10-20
公開日2005-10-26
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.35 Å)
主引用文献Alternative Mutations of a Positively Selected Residue Elicit Gain or Loss of Functionalities in Enzyme Evolution.
Proc.Natl.Acad.Sci.USA, 103, 2006
2C3T
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Human glutathione-S-transferase T1-1, W234R mutant, apo form
分子名称: GLUTATHIONE S-TRANSFERASE THETA 1
著者Tars, K, Larsson, A.-K, Shokeer, A, Olin, B, Mannervik, B, Kleywegt, G.J.
登録日2005-10-12
公開日2005-11-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3Q
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Human glutathione-S-transferase T1-1 W234R mutant, complex with S- hexylglutathione
分子名称: GLUTATHIONE S-TRANSFERASE THETA 1, IODIDE ION, S-HEXYLGLUTATHIONE
著者Tars, K, Larsson, A.-K, Shokeer, A, Olin, B, Mannervik, B, Kleywegt, G.J.
登録日2005-10-11
公開日2005-11-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2C3N
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BU of 2c3n by Molmil
Human glutathione-S-transferase T1-1, apo form
分子名称: GLUTATHIONE S-TRANSFERASE THETA 1, IODIDE ION
著者Tars, K, Larsson, A.-K, Shokeer, A, Olin, B, Mannervik, B, Kleywegt, G.J.
登録日2005-10-11
公開日2005-11-30
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structural Basis of the Suppressed Catalytic Activity of Wild-Type Human Glutathione Transferase T1-1 Compared to its W234R Mutant.
J.Mol.Biol., 355, 2006
2AB6
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HUMAN GLUTATHIONE S-TRANSFERASE M2-2 (E.C.2.5.1.18) complexed with S-METHYLGLUTATHIONE
分子名称: Glutathione S-transferase Mu 2, L-GAMMA-GLUTAMYL-S-METHYLCYSTEINYLGLYCINE
著者Patskovsky, Y, Almo, S.C, Listowsky, I.
登録日2005-07-14
公開日2005-08-02
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural Perturbations in the Active Site of Human Glutathione-S-Transferase M2-2 Upon Ligand Binding
To be Published
1YY7
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Crystal structure of stringent starvation protein A (SspA), an RNA polymerase-associated transcription factor
分子名称: CITRIC ACID, stringent starvation protein A
著者Hansen, A.-M, Gu, Y, Li, M, Andrykovitch, M, Waugh, D.S, Jin, D.J, Ji, X.
登録日2005-02-23
公開日2005-03-01
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Structural basis for the function of stringent starvation protein A as a transcription factor
J.Biol.Chem., 280, 2005
1YKC
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human glutathione S-transferase m2-2 (E.C.2.5.1.18) complexed with glutathione-disulfide
分子名称: Glutathione S-transferase Mu 2, OXIDIZED GLUTATHIONE DISULFIDE
著者Patskovsky, Y.V, Patskovska, L.N, Listowsky, I, Almo, S.C.
登録日2005-01-17
公開日2005-01-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Selective Inhibitors of Prostaglandin Synthase activity of human glutathione S-transferase M2-2
To be Published
1YJ6
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BU of 1yj6 by Molmil
crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-zinc-trihydroxide
分子名称: GLUTATHIONE, Glutathione S-transferase Mu 1, ZINC ION
著者Patskovsky, Y.V, Patskovska, L.N, Listowsky, I, Almo, S.C.
登録日2005-01-13
公開日2005-02-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Human Glutathione S-Transferase M1A-1A Catalyzes Formation of Gsh-Metal Complexes
To be Published
1YDK
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Crystal structure of the I219A mutant of human glutathione transferase A1-1 with S-hexylglutathione
分子名称: Glutathione S-transferase A1, S-HEXYLGLUTATHIONE
著者Kuhnert, D.C, Sayed, Y, Mosebi, S, Sayed, M, Sewell, T, Dirr, H.W.
登録日2004-12-24
公開日2005-06-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Tertiary Interactions Stabilise the C-terminal Region of Human Glutathione Transferase A1-1: a Crystallographic and Calorimetric Study.
J.Mol.Biol., 349, 2005
1XWK
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2.3 angstrom resolution crystal structure of human glutathione S-transferase M1A-1A complexed with glutathionyl-S-dinitrobenzene
分子名称: GLUTATHIONE S-(2,4 DINITROBENZENE), Glutathione S-transferase Mu 1
著者Patskovsky, Y, Patskovska, L, Almo, S.C, Listowsky, I.
登録日2004-11-01
公開日2004-12-21
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Transition state model and mechanism of nucleophilic aromatic substitution reactions catalyzed by human glutathione S-transferase M1a-1a.
Biochemistry, 45, 2006
1XWG
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Human GST A1-1 T68E mutant
分子名称: Glutathione S-transferase A1
著者Grahn, E, Jakobsson, E, Gustafsson, A, Novotny, M, Grehn, L, Olin, B, Madsen, D, Wahlberg, M, Mannervik, B, Kleywegt, G.J.
登録日2004-11-01
公開日2005-11-01
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献New crystal structures of human glutathione transferase A1-1 shed light on glutathione binding and the conformation of the C-terminal helix.
Acta Crystallogr.,Sect.D, 62, 2006

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