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6QD4
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MloK1 model from single particle analysis of 2D crystals, class 8 (intermediate conformation)
分子名称: Cyclic nucleotide-gated potassium channel mll3241, POTASSIUM ION
著者Righetto, R, Biyani, N, Kowal, J, Chami, M, Stahlberg, H.
登録日2018-12-31
公開日2019-04-24
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (5.6 Å)
主引用文献Retrieving high-resolution information from disordered 2D crystals by single-particle cryo-EM.
Nat Commun, 10, 2019
8EM8
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Co-crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum in complex with RY-1-165
分子名称: UNKNOWN ATOM OR ION, [(3R)-3-{[(4M)-4-(4-cyclopropyl-2-phenyl-1H-imidazol-1-yl)pyrimidin-2-yl]amino}pyrrolidin-1-yl](1,3-thiazol-2-yl)methanone, cGMP-dependent protein kinase, ...
著者Hutchinson, A, Dong, A, Seitova, A, Bhanot, P, Arrowsmith, C.H, Edwards, A.M, Halabelian, L, Structural Genomics Consortium (SGC)
登録日2022-09-27
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Co-crystal structure of the cGMP-dependent protein kinase PKG from Plasmodium falciparum in complex with RY-1-165
To Be Published
8EOW
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Eag Kv channel with voltage sensor in the up conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EP1
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Eag Kv channel with voltage sensor in the down conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EP0
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Eag Kv channel with voltage sensor in the intermediate conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
7W5Z
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Cryo-EM structure of Tetrahymena thermophila mitochondrial complex IV, composite dimer model
分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-oxoglutarate/malate carrier protein, CARDIOLIPIN, ...
著者Zhou, L, Maldonado, M, Padavannil, A, Letts, J.
登録日2021-11-30
公開日2022-04-06
最終更新日2022-06-01
実験手法ELECTRON MICROSCOPY (3.02 Å)
主引用文献Structures of Tetrahymena 's respiratory chain reveal the diversity of eukaryotic core metabolism.
Science, 376, 2022
8ETP
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Cryo-EM structure of cGMP bound closed state of human CNGA3/CNGB3 channel in GDN
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Zheng, X, Yang, J.
登録日2022-10-17
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (3.52 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EU3
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Cryo-EM structure of cGMP bound human CNGA3/CNGB3 channel in GDN, transition state 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Zheng, X, Yang, J.
登録日2022-10-18
公開日2023-08-02
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EVB
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Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, pre-open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Yang, J.
登録日2022-10-20
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EV8
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Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, closed state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Yang, J.
登録日2022-10-20
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.11 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EVC
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BU of 8evc by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, open state
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Yang, J.
登録日2022-10-20
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EV9
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BU of 8ev9 by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 1
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Yang, J.
登録日2022-10-20
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EVA
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BU of 8eva by Molmil
Cryo-EM structure of cGMP bound truncated human CNGA3/CNGB3 channel in lipid nanodisc, transition state 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Yang, J.
登録日2022-10-20
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.33 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
8EUC
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BU of 8euc by Molmil
Cryo-EM structure of cGMP bound human CNGA3/CNGB3 channel in GDN, transition state 2
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, CYCLIC GUANOSINE MONOPHOSPHATE, Cyclic nucleotide-gated cation channel alpha-3, ...
著者Hu, Z, Zheng, X, Yang, J.
登録日2022-10-18
公開日2023-08-09
実験手法ELECTRON MICROSCOPY (3.61 Å)
主引用文献Conformational trajectory of allosteric gating of the human cone photoreceptor cyclic nucleotide-gated channel.
Nat Commun, 14, 2023
7YIG
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BU of 7yig by Molmil
Human KCNH5 pre-open state 2
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.6 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIF
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BU of 7yif by Molmil
Human KCNH5 pre-open state 1
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIE
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BU of 7yie by Molmil
Human KCNH5-closed state 2
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YID
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BU of 7yid by Molmil
Human KCNH5 closed state 1
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIJ
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Human KCNH5 pore dilation but the non-conducting state
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
7YIH
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BU of 7yih by Molmil
Human KCNH5 open state
分子名称: POTASSIUM ION, Potassium voltage-gated channel subfamily H member 5
著者Zhang, M.F.
登録日2022-07-16
公開日2023-04-05
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism underlying delayed rectifying in human voltage-mediated activation Eag2 channel.
Nat Commun, 14, 2023
4AVB
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Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
著者Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
登録日2012-05-24
公開日2012-07-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4MGK
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Selective activation of Epac1 and Epac2
分子名称: ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, Rap guanine nucleotide exchange factor 4, Ras-related protein Rap-1b, ...
著者Rehmann, H.
登録日2013-08-28
公開日2014-09-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Selective activation of Epac1 and Epac2
To be Published
4MGZ
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Selective activation of Epac1 and Epac2
分子名称: (2S,4aR,6R,7R,7aS)-6-[6-amino-8-(benzylsulfanyl)-9H-purin-9-yl]-2-sulfanyltetrahydro-4H-furo[3,2-d][1,3,2]dioxaphosphinin-7-ol 2-oxide, Rap guanine nucleotide exchange factor 4, Ras-related protein Rap-1b, ...
著者Rehmann, H.
登録日2013-08-29
公開日2014-09-03
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Selective activation of Epac1 and Epac2
To be Published
4AVC
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BU of 4avc by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 in complex with acetyl CoA and cAMP
分子名称: 1,2-ETHANEDIOL, ACETYL COENZYME *A, ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE, ...
著者Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
登録日2012-05-24
公開日2012-07-11
最終更新日2012-08-22
実験手法X-RAY DIFFRACTION (2.806 Å)
主引用文献Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012
4AVA
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BU of 4ava by Molmil
Crystal structure of protein lysine acetyltransferase Rv0998 from Mycobacterium tuberculosis
分子名称: 1,2-ETHANEDIOL, ACETATE ION, ACETYL COENZYME *A, ...
著者Lee, H.J, Lang, P.T, Fortune, S.M, Sassetti, C.M, Alber, T.
登録日2012-05-24
公開日2012-07-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.698 Å)
主引用文献Cyclic AMP Regulation of Protein Lysine Acetylation in Mycobacterium Tuberculosis.
Nat.Struct.Mol.Biol., 19, 2012

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件を2024-05-29に公開中

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