Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 241 件
5KG2
DownloadVisualize
BU of 5kg2 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 37 degree
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KG5
DownloadVisualize
BU of 5kg5 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 10 mM Cd2+ for 60s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFM
DownloadVisualize
BU of 5kfm by Molmil
Human DNA polymerase eta-DNA ternary complex with Sp-dATP-alpha-S: ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
分子名称: 2'-DEOXYADENOSINE 5'-O-(1-THIOTRIPHOSPHATE), CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
7U78
DownloadVisualize
BU of 7u78 by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 1.0 mM Mg2+ for 80s
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
5L1L
DownloadVisualize
BU of 5l1l by Molmil
PostInsertion complex of Human DNA Polymerase Eta bypassing an O6-Methyl-2'-deoxyguanosine : dT site
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*GP*(6OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Patra, A, Egli, M.
登録日2016-07-29
公開日2016-10-05
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Mechanisms of Insertion of dCTP and dTTP Opposite the DNA Lesion O6-Methyl-2'-deoxyguanosine by Human DNA Polymerase eta.
J.Biol.Chem., 291, 2016
5KG1
DownloadVisualize
BU of 5kg1 by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction first with 1 mM Mn2+ for 1800s then with 5 mM Mn2+ for 60s at 30 degree
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFW
DownloadVisualize
BU of 5kfw by Molmil
Human DNA polymerase eta R61A-DNA ternary complex: reaction with 1 mM Mg2+ for 200s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
4O3R
DownloadVisualize
BU of 4o3r by Molmil
Crystal structure of human polymerase eta extending an 8-oxog dna lesion: post insertion of 8-oxog-da pair
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]cytidine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*A)-3'), DNA (5'-D(*CP*AP*TP*GP*(8OG)P*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Patra, A, Egli, M.
登録日2013-12-18
公開日2014-04-30
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.62 Å)
主引用文献Kinetics, Structure, and Mechanism of 8-Oxo-7,8-dihydro-2'-deoxyguanosine Bypass by Human DNA Polymerase eta
J.Biol.Chem., 289, 2014
7U7R
DownloadVisualize
BU of 7u7r by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex:no Me2+ soaking
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
8G8H
DownloadVisualize
BU of 8g8h by Molmil
Crystal structure of human DNA polymerase eta incorporating ITP across dC
分子名称: CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*GP*AP*G)-3'), DNA (5'-D(P*AP*TP*CP*CP*TP*CP*AP*CP*GP*CP*T)-3'), ...
著者Jung, H.
登録日2023-02-17
公開日2024-02-21
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献Crystal structure of human DNA polymerase eta incorporating ITP across dC
To Be Published
7U7F
DownloadVisualize
BU of 7u7f by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 90s
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7X
DownloadVisualize
BU of 7u7x by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 2.0 mM Mg2+ for 600s
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7V
DownloadVisualize
BU of 7u7v by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.4 mM Mg2+ for 600s
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
5KFL
DownloadVisualize
BU of 5kfl by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 600s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*A)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
8V7K
DownloadVisualize
BU of 8v7k by Molmil
Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 10 mM Mn2+ for 1800s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*(CAR))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Chang, C, Gao, Y.
登録日2023-12-04
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 10 mM Mn2+ for 1800s
To Be Published
5KFD
DownloadVisualize
BU of 5kfd by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 1 mM Mn2+ for 300s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
5KFI
DownloadVisualize
BU of 5kfi by Molmil
Human DNA polymerase eta-DNA ternary complex: reaction with 10 mM Mn2+ for 120s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Gao, Y, Yang, W.
登録日2016-06-12
公開日2016-06-29
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.65 Å)
主引用文献Capture of a third Mg2+ is essential for catalyzing DNA synthesis.
Science, 352, 2016
4ED0
DownloadVisualize
BU of 4ed0 by Molmil
Human DNA polymerase eta - DNA ternary complex: AT crystal at pH 6.8 (Na+ MES) with 1 Ca2+ ion
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Nakamura, T, Zhao, Y, Yang, W.
登録日2012-03-26
公開日2012-07-11
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (1.653 Å)
主引用文献Watching DNA polymerase eta make a phosphodiester bond
Nature, 487, 2012
5EWE
DownloadVisualize
BU of 5ewe by Molmil
Ternary complex of human DNA polymerase eta inserting rCTP opposite template G
分子名称: CALCIUM ION, CYTIDINE-5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ...
著者Su, Y, Egli, M, Guengerich, F.P.
登録日2015-11-20
公開日2016-01-13
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Mechanism of Ribonucleotide Incorporation by Human DNA Polymerase eta.
J.Biol.Chem., 291, 2016
7U7W
DownloadVisualize
BU of 7u7w by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 1.0 mM Mg2+ for 600s
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7M88
DownloadVisualize
BU of 7m88 by Molmil
Human DNA Pol eta S113A with dA-ended primer and dATP: in crystallo reaction for 300 s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DIPHOSPHATE, ...
著者Gregory, M.T, Gao, Y, Yang, W.
登録日2021-03-29
公開日2021-06-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Multiple deprotonation paths of the nucleophile 3'-OH in the DNA synthesis reaction.
Proc.Natl.Acad.Sci.USA, 118, 2021
8V7J
DownloadVisualize
BU of 8v7j by Molmil
Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 20 mM Mg2+ for 600s
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*(CAR))-3'), DNA (5'-D(*CP*AP*TP*TP*GP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Chang, C, Gao, Y.
登録日2023-12-04
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.66 Å)
主引用文献Human DNA polymerase eta-DNA-araC-ended primer ternary complex:reaction with 20 mM Mg2+ for 600s
To Be Published
7U7Z
DownloadVisualize
BU of 7u7z by Molmil
Human DNA polymerase eta-DNA-dGMPNPP ternary mismatch complex in 0.12 mM Mn2+ for 600s
分子名称: 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]guanosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*TP*AP*TP*GP*AP*CP*GP*CP*T)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
7U7K
DownloadVisualize
BU of 7u7k by Molmil
Human DNA polymerase eta-DNA ternary mismatch complex:reaction with 10.0 mM Mn2+ for 600s
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DIPHOSPHATE, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*TP*G)-3'), ...
著者Chang, C, Gao, Y.
登録日2022-03-07
公開日2022-05-04
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献In crystallo observation of three metal ion promoted DNA polymerase misincorporation.
Nat Commun, 13, 2022
8V7H
DownloadVisualize
BU of 8v7h by Molmil
Human DNA polymerase eta-DNA-araC-ended primer ternary complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
分子名称: 2'-DEOXYADENOSINE 5'-TRIPHOSPHATE, CALCIUM ION, DNA (5'-D(*AP*GP*CP*GP*TP*CP*A)-R(P*(CAR))-3'), ...
著者Chang, C, Gao, Y.
登録日2023-12-04
公開日2024-05-15
実験手法X-RAY DIFFRACTION (1.68 Å)
主引用文献Human DNA polymerase eta-DNA-araC-ended primer ternary complex:ground state at pH7.0 (K+ MES) with 1 Ca2+ ion
To Be Published

226262

件を2024-10-16に公開中

PDB statisticsPDBj update infoContact PDBjnumon