8UDL
| Human Mitochondrial DNA Polymerase Gamma Binary Complex | 分子名称: | DNA (5'-D(P*AP*AP*AP*AP*CP*GP*AP*CP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*AP*TP*AP*C)-3'), DNA (5'-D(P*AP*GP*GP*TP*AP*TP*GP*GP*CP*AP*CP*TP*GP*GP*CP*CP*GP*TP*CP*GP*TP*TP*TP*T)-3'), DNA polymerase subunit gamma-1, ... | 著者 | Park, J, Yin, Y.W. | 登録日 | 2023-09-28 | 公開日 | 2024-06-05 | 実験手法 | ELECTRON MICROSCOPY (2.37 Å) | 主引用文献 | An interaction network in the polymerase active site is a prerequisite for Watson-Crick base pairing in Pol gamma. Sci Adv, 10, 2024
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8D33
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8G5M
| Cryo-EM structure of the Mismatch Locking Complex (III) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.58 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5O
| Cryo-EM structure of the Guide loop Engagement Complex (IV) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.61 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5J
| Cryo-EM structure of the Mismatch Uncoupling Complex (II) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.63 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8D37
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8G5N
| Cryo-EM structure of the Guide loop Engagement Complex (VI) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.73 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5I
| Cryo-EM structure of the Mismatch Sensing Complex (I) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.75 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5P
| Cryo-EM structure of the Guide loop Engagement Complex (V) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.78 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8G5K
| Cryo-EM structure of the Wedge Alignment Complex (VIII) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8D42
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8G5L
| Cryo-EM structure of the Primer Separation Complex (IX) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-02-13 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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8V5R
| Active conformation of DNA polymerase gamma bound to DNA | 分子名称: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, ... | 著者 | Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C. | 登録日 | 2023-11-30 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 2024
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8D3R
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8T7E
| Cryo-EM structure of the Backtracking Initiation Complex (VII) of Human Mitochondrial DNA Polymerase Gamma | 分子名称: | DNA polymerase subunit gamma-1, DNA polymerase subunit gamma-2, mitochondrial, ... | 著者 | Nayak, A.R, Buchel, G, Herbine, K.H, Sarfallah, A, Sokolova, V.O, Zamudio-Ochoa, A, Temiakov, D. | 登録日 | 2023-06-20 | 公開日 | 2024-01-10 | 実験手法 | ELECTRON MICROSCOPY (3.08 Å) | 主引用文献 | Structural basis for DNA proofreading. Nat Commun, 14, 2023
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3IKL
| Crystal structure of Pol gB delta-I4. | 分子名称: | DNA polymerase subunit gamma-2, mitochondrial | 著者 | Lee, Y.S, Kennedy, W.D, Yin, Y.W. | 登録日 | 2009-08-06 | 公開日 | 2010-08-25 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structural insight into processive human mitochondrial DNA synthesis and disease-related polymerase mutations. Cell(Cambridge,Mass.), 139, 2009
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2G4C
| Crystal Structure of human DNA polymerase gamma accessory subunit | 分子名称: | DNA polymerase gamma subunit 2 | 著者 | Fan, L, Farr, C.L, Kaguni, L.S, Tainer, J.A. | 登録日 | 2006-02-22 | 公開日 | 2006-04-18 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.15 Å) | 主引用文献 | A novel processive mechanism for DNA synthesis revealed by structure, modeling and mutagenesis of the accessory subunit of human mitochondrial DNA polymerase J.Mol.Biol., 358, 2006
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3IKM
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4ZTU
| Structural basis for processivity and antiviral drug toxicity in human mitochondrial DNA replicase | 分子名称: | 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*AP*GP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... | 著者 | Szymanski, M.R, Kuznestov, V.B, Shumate, C.K, Meng, Q, Lee, Y.-S, Patel, G, Patel, S.S, Yin, Y.W. | 登録日 | 2015-05-15 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.299 Å) | 主引用文献 | Structural basis for processivity and antiviral drug toxicity
in human mitochondrial DNA replicase EMBO J., 34, 2015
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5C51
| Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | 分子名称: | DNA, DNA (5'-D(*(AD)P*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Whitney, Y.Y. | 登録日 | 2015-06-19 | 公開日 | 2016-05-11 | 最終更新日 | 2016-05-18 | 実験手法 | X-RAY DIFFRACTION (3.426 Å) | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. Proc.Natl.Acad.Sci.USA, 112, 2015
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8UDK
| Human Mitochondrial DNA Polymerase gamma R853A Ternary Complex | 分子名称: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA (24-MER), DNA (28-MER), ... | 著者 | Park, J, Herrmann, G.K, Yin, Y.W. | 登録日 | 2023-09-28 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (3.43 Å) | 主引用文献 | An interaction network in the polymerase active site is a prerequisite for Watson-Crick base pairing in Pol gamma. Sci Adv, 10, 2024
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4ZTZ
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5C53
| Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | 分子名称: | 2',3'-DIDEOXYCYTIDINE-5'-MONOPHOSPHATE, DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), ... | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | 登録日 | 2015-06-19 | 公開日 | 2016-01-27 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.567 Å) | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. Proc.Natl.Acad.Sci.USA, 112, 2015
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5C52
| Probing the Structural and Molecular Basis of Nucleotide Selectivity by Human Mitochondrial DNA Polymerase gamma | 分子名称: | DNA (26-MER), DNA (5'-D(*AP*AP*AP*AP*CP*GP*AP*GP*GP*GP*CP*CP*AP*GP*TP*GP*CP*CP*GP*TP*AP*C)-3'), DNA polymerase subunit gamma-1, ... | 著者 | Sohl, C.D, Szymanski, M.R, Mislak, A.C, Shumate, C.K, Amiralaei, S, Schinazi, R.F, Anderson, K.S, Yin, Y.W. | 登録日 | 2015-06-19 | 公開日 | 2016-05-11 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3.637 Å) | 主引用文献 | Probing the structural and molecular basis of nucleotide selectivity by human mitochondrial DNA polymerase gamma. Proc.Natl.Acad.Sci.USA, 112, 2015
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8V54
| Engaged conformation of the human mitochondrial DNA polymerase gamma bound to DNA | 分子名称: | DNA (25-MER), DNA (44-MER), DNA polymerase subunit gamma-1, ... | 著者 | Riccio, A.A, Krahn, J.M, Bouvette, J, Borgnia, J.M, Copeland, W.C. | 登録日 | 2023-11-30 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | Coordinated DNA polymerization by Pol gamma and the region of LonP1 regulated proteolysis. Nucleic Acids Res., 2024
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