Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 10 件
7V8Y
DownloadVisualize
BU of 7v8y by Molmil
Crystal structure of mouse CRY2 in complex with SHP1703 compound
分子名称: 1-[(2R)-3-[3,6-bis(fluoranyl)carbazol-9-yl]-2-oxidanyl-propyl]imidazolidin-2-one, Cryptochrome-2
著者Miller, S.A, Hirota, T.
登録日2021-08-23
公開日2022-08-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy.
Proc.Natl.Acad.Sci.USA, 119, 2022
4MLP
DownloadVisualize
BU of 4mlp by Molmil
Mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase
分子名称: Cryptochrome-2, N-[(2S)-3-(9H-carbazol-9-yl)-2-hydroxypropyl]-N-(furan-2-ylmethyl)methanesulfonamide
著者Nangle, S, Xing, W, Zheng, N.
登録日2013-09-06
公開日2013-10-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.943 Å)
主引用文献Crystal structure of mammalian cryptochrome in complex with a small molecule competitor of its ubiquitin ligase.
Cell Res., 23, 2013
7V8Z
DownloadVisualize
BU of 7v8z by Molmil
Crystal structure of mouse CRY2 in complex with SHP656 compound
分子名称: 1-[(2R)-3-[3,6-bis(fluoranyl)carbazol-9-yl]-2-oxidanyl-propyl]imidazolidin-2-one, Cryptochrome-2
著者Miller, S.A, Hirota, T.
登録日2021-08-23
公開日2022-08-24
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献CRY2 isoform selectivity of a circadian clock modulator with antiglioblastoma efficacy.
Proc.Natl.Acad.Sci.USA, 119, 2022
4I6G
DownloadVisualize
BU of 4i6g by Molmil
a vertebrate cryptochrome with FAD
分子名称: Cryptochrome-2, FLAVIN-ADENINE DINUCLEOTIDE
著者Xing, W, Busino, L, Hinds, T.R, Marionni, S.T, Saifee, N.H, Bush, M.F, Pagano, M, Zheng, N.
登録日2012-11-29
公開日2013-03-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket.
Nature, 496, 2013
6KX8
DownloadVisualize
BU of 6kx8 by Molmil
Crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2019-09-10
公開日2020-04-01
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Isoform-selective regulation of mammalian cryptochromes.
Nat.Chem.Biol., 16, 2020
7EJ9
DownloadVisualize
BU of 7ej9 by Molmil
Alternative crystal structure of mouse Cryptochrome 2 in complex with TH301 compound
分子名称: 1-(4-chlorophenyl)-N-[2-(4-methoxyphenyl)-5,5-bis(oxidanylidene)-4,6-dihydrothieno[3,4-c]pyrazol-3-yl]cyclopentane-1-carboxamide, Cryptochrome-2
著者Miller, S.A, Hirota, T.
登録日2021-04-01
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021
4I6E
DownloadVisualize
BU of 4i6e by Molmil
A vertebrate cryptochrome
分子名称: Cryptochrome-2
著者Xing, W, Busino, L, Hinds, T.R, Marionni, S.T, Saifee, N.H, Bush, M.F, Pagano, M, Zheng, N.
登録日2012-11-29
公開日2013-03-13
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket.
Nature, 496, 2013
4I6J
DownloadVisualize
BU of 4i6j by Molmil
A ubiquitin ligase-substrate complex
分子名称: Cryptochrome-2, F-box/LRR-repeat protein 3, S-phase kinase-associated protein 1
著者Xing, W, Busino, L, Hinds, T.R, Marionni, S.T, Saifee, N.H, Bush, M.F, Pagano, M, Zheng, N.
登録日2012-11-29
公開日2013-03-13
最終更新日2013-05-01
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献SCFFBXL3 ubiquitin ligase targets cryptochromes at their cofactor pocket.
Nature, 496, 2013
4U8H
DownloadVisualize
BU of 4u8h by Molmil
Crystal Structure of Mammalian Period-Cryptochrome Complex
分子名称: Cryptochrome-2, Period circadian protein homolog 2, ZINC ION
著者Nangle, S.N, Rosensweig, C, Koike, N, Tei, H, Takahashi, J.S, Green, C.B, Zheng, N.
登録日2014-08-03
公開日2014-10-01
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.798 Å)
主引用文献Molecular assembly of the period-cryptochrome circadian transcriptional repressor complex.
Elife, 3, 2014
7D0N
DownloadVisualize
BU of 7d0n by Molmil
Crystal structure of mouse CRY2 apo form
分子名称: Cryptochrome-2
著者Miller, S.A, Aikawa, Y, Hirota, T.
登録日2020-09-11
公開日2021-06-23
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural differences in the FAD-binding pockets and lid loops of mammalian CRY1 and CRY2 for isoform-selective regulation.
Proc.Natl.Acad.Sci.USA, 118, 2021

222415

件を2024-07-10に公開中

PDB statisticsPDBj update infoContact PDBjnumon