3GUA
 
 | | Sulfates bound in the vestibule of AChBP | | 分子名称: | SULFATE ION, Soluble acetylcholine receptor | | 著者 | Hansen, S.B, Taylor, P. | | 登録日 | 2009-03-28 | | 公開日 | 2009-07-14 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | An Ion Selectivity Filter in the Extracellular Domain of Cys-loop Receptors Reveals Determinants for Ion Conductance
J.Biol.Chem., 283, 2008
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2XZ6
 | | MTSET-modified Y53C mutant of Aplysia AChBP | | 分子名称: | 2-(TRIMETHYLAMMONIUM)ETHYL THIOL, SOLUBLE ACETYLCHOLINE RECEPTOR | | 著者 | Brams, M, Gay, E.A, Colon Saez, J, Guskov, A, Van Elk, R, Van Der Schors, R.C, Peigneur, S, Tytgat, J, Strelkov, S.V, Smit, A.B, Yakel, J.L, Ulens, C. | | 登録日 | 2010-11-23 | | 公開日 | 2010-12-08 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.137 Å) | | 主引用文献 | Crystal Structures of a Cysteine-Modified Mutant in Loop D of Acetylcholine Binding Protein
J.Biol.Chem., 286, 2011
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5OAL
 | | Crystal structure of mutant AChBP in complex with strychnine (T53F, Q74R, Y110A, I135S, G162E) | | 分子名称: | ARGININE, STRYCHNINE, Soluble acetylcholine receptor | | 著者 | Dawson, A, Hunter, W.N, de Souza, J.O, Trumper, P. | | 登録日 | 2017-06-22 | | 公開日 | 2018-08-01 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Engineering a surrogate human heteromeric alpha / beta glycine receptor orthosteric site exploiting the structural homology and stability of acetylcholine-binding protein.
Iucrj, 6, 2019
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4AFT
 | | Aplysia californica AChBP in complex with Varenicline | | 分子名称: | SOLUBLE ACETYLCHOLINE RECEPTOR, VARENICLINE | | 著者 | Rucktooa, P, Haseler, C.A, vanElke, R, Smit, A.B, Gallagher, T, Sixma, T.K. | | 登録日 | 2012-01-23 | | 公開日 | 2012-05-02 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors Through Study of Ligand Complexes with Acetylcholine-Binding Protein.
J.Biol.Chem., 287, 2012
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2XNT
 | | Acetylcholine binding protein (AChBP) as template for hierarchical in silico screening procedures to identify structurally novel ligands for the nicotinic receptors | | 分子名称: | (2S)-2-[(4-CHLOROBENZYL)OXY]-2-PHENYLETHANAMINE, BROMIDE ION, SOLUBLE ACETYLCHOLINE RECEPTOR | | 著者 | Rucktooa, P, Akdemir, A, deEsch, I, Sixma, T.K. | | 登録日 | 2010-08-06 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.21 Å) | | 主引用文献 | Acetylcholine Binding Protein (Achbp) as Template for Hierarchical in Silico Screening Procedures to Identify Structurally Novel Ligands for the Nicotinic Receptors.
Bioorg.Med.Chem., 19, 2011
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2Y58
 | | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and thermodynamic analysis - (Compound 6) | | 分子名称: | CHLORIDE ION, SOLUBLE ACETYLCHOLINE RECEPTOR, SULFATE ION, ... | | 著者 | Rucktooa, P, Edink, E, deEsch, I.J.P, Sixma, T.K. | | 登録日 | 2011-01-12 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
J.Am.Chem.Soc., 133, 2011
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2Y57
 | | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and thermodynamic analysis - (Compound 4) | | 分子名称: | CHLORIDE ION, SOLUBLE ACETYLCHOLINE RECEPTOR, SULFATE ION, ... | | 著者 | Rucktooa, P, Edink, E, deEsch, I.J.P, Sixma, T.K. | | 登録日 | 2011-01-12 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | | 主引用文献 | Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
J.Am.Chem.Soc., 133, 2011
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2BYQ
 | | Crystal structure of Aplysia californica AChBP in complex with epibatidine | | 分子名称: | EPIBATIDINE, SOLUBLE ACETYLCHOLINE RECEPTOR | | 著者 | Hansen, S.B, Sulzenbacher, G, Huxford, T, Marchot, P, Taylor, P, Bourne, Y. | | 登録日 | 2005-08-03 | | 公開日 | 2005-10-05 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Structures of Aplysia Achbp Complexes with Nicotinic Agonists and Antagonists Reveal Distinctive Binding Interfaces and Conformations.
Embo J., 24, 2005
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5XGL
 | | Co-crystal structure of Ac-AChBPP in complex with alpha-conotoxin LvIA | | 分子名称: | Alpha-conotoxin LvIA, Soluble acetylcholine receptor | | 著者 | Wang, X.Q, Xu, M.Y, Luo, S.L, Zhu, X.P. | | 登録日 | 2017-04-14 | | 公開日 | 2018-06-13 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.439 Å) | | 主引用文献 | The crystal structure of Ac-AChBP in complex with alpha-conotoxin LvIA reveals the mechanism of its selectivity towards different nAChR subtypes
Protein Cell, 8, 2017
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2Y56
 | | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and thermodynamic analysis - (Compound 3) | | 分子名称: | CHLORIDE ION, GLYCEROL, SOLUBLE ACETYLCHOLINE RECEPTOR, ... | | 著者 | Rucktooa, P, Edink, E, deEsch, I.J.P, Sixma, T.K. | | 登録日 | 2011-01-12 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.59 Å) | | 主引用文献 | Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
J.Am.Chem.Soc., 133, 2011
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2Y54
 | | Fragment growing induces conformational changes in acetylcholine- binding protein: A structural and thermodynamic analysis - (Fragment 1) | | 分子名称: | CHLORIDE ION, SOLUBLE ACETYLCHOLINE RECEPTOR, SULFATE ION, ... | | 著者 | Rucktooa, P, Edink, E, deEsch, I.J.P, Sixma, T.K. | | 登録日 | 2011-01-12 | | 公開日 | 2011-06-15 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Fragment Growing Induces Conformational Changes in Acetylcholine-Binding Protein: A Structural and Thermodynamic Analysis.
J.Am.Chem.Soc., 133, 2011
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