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PDB: 11 件

1QZ0
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Crystal Structure of the Yersinia Pestis Phosphatase YopH in Complex with a Phosphotyrosyl Mimetic-Containing Hexapeptide
分子名称: ASP-ALA-ASP-GLU-FTY-LEU-NH2, Protein-tyrosine phosphatase yopH
著者Phan, J, Lee, K, Cherry, S, Tropea, J.E, Burke Jr, T.R, Waugh, D.S.
登録日2003-09-15
公開日2003-11-25
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献High-Resolution Structure of the Yersinia pestis Protein Tyrosine Phosphatase YopH in Complex with a Phosphotyrosyl Mimetic-Containing Hexapeptide
Biochemistry, 42, 2003
2Y2F
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Crystal structure of Yersinia pestis YopH in complex with an aminooxy- containing platform compound for inhibitor design
分子名称: PROTEIN-TYROSINE PHOSPHATASE YOPH, [4-[3-(DIFLUORO-PHOSPHONO-METHYL)PHENYL]PHENYL]METHOXYAZANIUM
著者Lountos, G.T, Bahta, M, Dyas, B, Ulrich, R.G, Waugh, D.S, Burke, T.R.
登録日2010-12-14
公開日2011-03-16
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Utilization of Nitrophenylphosphates and Oxime-Based Ligation for the Development of Nanomolar Affinity Inhibitors of the Yersinia Pestis Outer Protein H (Yoph) Phosphatase.
J.Med.Chem., 54, 2011
2YDU
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Crystal structure of YopH in complex with 3-(1,1-dioxido-3- oxoisothiazolidin-5-yl)benzaldeyde
分子名称: 3-[(2S)-1,1-DIOXIDO-4-OXOTETRAHYDROTHIOPHEN-2-YL]BENZALDEHYDE, OUTER PROTEIN H PHOSPHATASE
著者Lountos, G.T, Kim, S.E, Bahta, M, Ulrich, R.G, Waugh, D.S, Burke, T.R.
登録日2011-03-24
公開日2011-11-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.79 Å)
主引用文献Isothiazolidinone (Izd) as a Phosphoryl Mimetic in Inhibitors of the Yersinia Pestis Protein Tyrosine Phosphatase Yoph.
Acta Crystallogr.,Sect.D, 67, 2011
6DR7
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YopH PTP1B WPD loop Chimera 2 PTPase bound to vanadate
分子名称: ACETATE ION, Targeted effector protein, VANADATE ION
著者Moise, G, Morales, Y, Johnson, S.J, Hengge, A.C.
登録日2018-06-11
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.849 Å)
主引用文献A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
Biochemistry, 57, 2018
6DR9
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Crystal Structure of the YopH PTP1B Chimera 3 PTPase apo form
分子名称: Targeted effector protein
著者Morales, Y, Johnson, S.J, Hengge, A.C.
登録日2018-06-11
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.945 Å)
主引用文献A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
Biochemistry, 57, 2018
1HUF
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CRYSTAL STRUCTURE OF THE N-TERMINAL DOMAIN OF THE TYROSINE PHOSPHATASE YOPH FROM YERSINIA PESTIS.
分子名称: TYROSINE PHOSPHATASE YOPH
著者Evdokimov, A.G, Waugh, D.S.
登録日2001-01-04
公開日2001-05-23
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure of the N-terminal domain of Yersinia pestis YopH at 2.0 A resolution.
Acta Crystallogr.,Sect.D, 57, 2001
7L0M
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Vanadate-bound YopH G352T
分子名称: Protein-tyrosine-phosphatase, VANADATE ION
著者Shen, R.D, Hengge, A.C, Johnson, S.J.
登録日2020-12-11
公開日2021-05-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases.
Jacs Au, 1, 2021
7L0I
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Ligand-free YopH G352T
分子名称: 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Protein-tyrosine-phosphatase
著者Shen, R.D, Hengge, A.C, Johnson, S.J.
登録日2020-12-11
公開日2021-05-12
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.02 Å)
主引用文献Single Residue on the WPD-Loop Affects the pH Dependency of Catalysis in Protein Tyrosine Phosphatases.
Jacs Au, 1, 2021
6DT6
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Crystal Structure of the YopH PTP1B Chimera 3 PTPase bound to vanadate
分子名称: Targeted effector protein, VANADATE ION
著者Morales, Y, Johnson, S.J, Hengge, A.C.
登録日2018-06-15
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.101 Å)
主引用文献A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
Biochemistry, 57, 2018
6DR1
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YopH PTP1B Chimera 2 PTPase
分子名称: Targeted effector protein
著者Morales, Y, Johnson, S.J, Hengge, A.C.
登録日2018-06-11
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
Biochemistry, 57, 2018
6DRB
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Crystal Structure of the YopH PTP1B WPD loop Chimera 3 PTPase bound to tungstate
分子名称: TUNGSTATE(VI)ION, Targeted effector protein
著者Morales, Y, Johnson, S.J, Hengge, A.C.
登録日2018-06-11
公開日2018-08-29
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.745 Å)
主引用文献A YopH PTP1B Chimera Shows the Importance of the WPD-Loop Sequence to the Activity, Structure, and Dynamics of Protein Tyrosine Phosphatases.
Biochemistry, 57, 2018

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件を2024-07-10に公開中

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