2YDU

Crystal structure of YopH in complex with 3-(1,1-dioxido-3- oxoisothiazolidin-5-yl)benzaldeyde

Summary for 2YDU

• Entry DOI: 10.2210/pdb2ydu/pdb
• Related: 1QZ0 2Y2F
• Descriptor: OUTER PROTEIN H PHOSPHATASE, 3-[(2S)-1,1-DIOXIDO-4-OXOTETRAHYDROTHIOPHEN-2-YL]BENZALDEHYDE (3 entities in total)
• Functional Keywords: hydrolase, antiplague drug design
• Biological source: YERSINIA PESTIS
• Total number of polymer chains: 1
• Total formula weight: 33792.14

Authors

Lountos, G.T.,Kim, S.E.,Bahta, M.,Ulrich, R.G.,Waugh, D.S.,Burke, T.R. (deposition date: 2011-03-24, release date: 2011-11-02, Last modification date: 2023-12-20)

• Primary citation: Kim, S.E.,Bahta, M.,Lountos, G.T.,Ulrich, R.G.,Burke, T.R.,Waugh, D.S.; Isothiazolidinone (Izd) as a Phosphoryl Mimetic in Inhibitors of the Yersinia Pestis Protein Tyrosine Phosphatase Yoph.; Acta Crystallogr.,Sect.D, 67:639-, 2011; PubMed: 21697602; DOI: 10.1107/S0907444911018610

Experimental method

X-RAY DIFFRACTION (1.79 Å)