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PDB: 9 件

2PXR
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BU of 2pxr by Molmil
Crystal Structure of HIV-1 CA146 in the Presence of CAP-1
分子名称: CHLORIDE ION, Gag-Pol polyprotein (Pr160Gag-Pol), ZINC ION
著者Kelly, B.N.
登録日2007-05-14
公開日2007-09-25
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the Antiviral Assembly Inhibitor CAP-1 Complex with the HIV-1 CA Protein.
J.Mol.Biol., 373, 2007
4E91
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BU of 4e91 by Molmil
Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BD3
分子名称: (3S)-1-ethyl-3-[3-hydroxy-5-(pyridin-3-yl)phenyl]-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione, 4-{2-[5-(3-chlorophenyl)-1H-pyrazol-4-yl]-1-[3-(1H-imidazol-1-yl)propyl]-1H-benzimidazol-5-yl}benzoic acid, Gag protein, ...
著者Lemke, C.T.
登録日2012-03-20
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein.
J.Virol., 86, 2012
4J93
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Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BI-1
分子名称: (4S)-3-phenyl-4-(pyridin-3-yl)-4,5-dihydropyrrolo[3,4-c]pyrazol-6(2H)-one, 4-{2-[5-(3-chlorophenyl)-1H-pyrazol-4-yl]-1-[3-(1H-imidazol-1-yl)propyl]-1H-benzimidazol-5-yl}benzoic acid, Gag protein
著者Lemke, C.T.
登録日2013-02-15
公開日2013-07-10
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.74 Å)
主引用文献Discovery of Novel Small-Molecule HIV-1 Replication Inhibitors That Stabilize Capsid Complexes.
Antimicrob.Agents Chemother., 57, 2013
4INB
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BU of 4inb by Molmil
Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With benzodiazepine Inhibitor
分子名称: (3Z)-3-{[(2-methoxyethyl)amino]methylidene}-1-methyl-5-phenyl-7-(trifluoromethyl)-1H-1,5-benzodiazepine-2,4(3H,5H)-dione, Gag protein, SODIUM ION
著者Coulombe, R.
登録日2013-01-04
公開日2013-02-27
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Monitoring Binding of HIV-1 Capsid Assembly Inhibitors Using (19) F Ligand-and (15) N Protein-Based NMR and X-ray Crystallography: Early Hit Validation of a Benzodiazepine Series.
Chemmedchem, 8, 2013
4E92
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BU of 4e92 by Molmil
Crystal Structure of the N-Terminal Domain of HIV-1 Capsid in Complex With Inhibitor BM4
分子名称: 3-{5-[3-ethyl-5-(5-methylfuran-2-yl)-1H-pyrazol-1-yl]-1-[(6-oxo-1,6-dihydropyridin-3-yl)methyl]-1H-benzimidazol-2-yl}-4-hydroxybenzoic acid, 4-{2-[5-(3-chlorophenyl)-1H-pyrazol-4-yl]-1-[3-(1H-imidazol-1-yl)propyl]-1H-benzimidazol-5-yl}benzoic acid, Gag protein
著者Lemke, C.T.
登録日2012-03-20
公開日2012-04-25
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Distinct Effects of Two HIV-1 Capsid Assembly Inhibitor Families That Bind the Same Site within the N-Terminal Domain of the Viral CA Protein.
J.Virol., 86, 2012
3J4F
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BU of 3j4f by Molmil
Structure of HIV-1 capsid protein by cryo-EM
分子名称: capsid protein
著者Zhao, G, Perilla, J.R, Meng, X, Schulten, K, Zhang, P.
登録日2013-07-11
公開日2013-07-24
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
3J34
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BU of 3j34 by Molmil
Structure of HIV-1 Capsid Protein by Cryo-EM
分子名称: capsid protein
著者Zhao, G, Perilla, J.R, Yufenyuy, E, Meng, X, Chen, B, Ning, J, Ahn, J, Gronenborn, A.M, Schulten, K, Aiken, C, Zhang, P.
登録日2013-02-23
公開日2013-05-29
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY (8.6 Å)
主引用文献Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
3J3Y
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BU of 3j3y by Molmil
Atomic-level structure of the entire HIV-1 capsid (186 hexamers + 12 pentamers)
分子名称: capsid protein
著者Perilla, J.R, Zhao, G, Zhang, P, Schulten, K.J.
登録日2013-05-06
公開日2013-05-29
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY
主引用文献Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013
3J3Q
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BU of 3j3q by Molmil
Atomic-level structure of the entire HIV-1 capsid
分子名称: capsid protein
著者Perilla, J.R, Zhao, G, Zhang, P, Schulten, K.J.
登録日2013-04-12
公開日2013-05-29
最終更新日2018-07-18
実験手法ELECTRON MICROSCOPY
主引用文献Mature HIV-1 capsid structure by cryo-electron microscopy and all-atom molecular dynamics.
Nature, 497, 2013

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件を2024-07-10に公開中

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