2Z0P
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![BU of 2z0p by Molmil](/molmil-images/mine/2z0p) | Crystal structure of PH domain of Bruton's tyrosine kinase | 分子名称: | (2R)-3-{[(S)-{[(2S,3R,5S,6S)-2,6-DIHYDROXY-3,4,5-TRIS(PHOSPHONOOXY)CYCLOHEXYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-(1-HYDROXY BUTOXY)PROPYL BUTYRATE, Tyrosine-protein kinase BTK, ZINC ION | 著者 | Murayama, K, Kato-Murayama, M, Mishima, C, Shirouzu, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | 登録日 | 2007-05-07 | 公開日 | 2008-05-13 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.58 Å) | 主引用文献 | Crystal structure of the Bruton's tyrosine kinase PH domain with phosphatidylinositol Biochem.Biophys.Res.Commun., 377, 2008
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5XYZ
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![BU of 5xyz by Molmil](/molmil-images/mine/5xyz) | The structure of human BTK kinase domain in complex with a covalent inhibitor | 分子名称: | N-[3-(5-{[(2-chloro-6-fluorophenyl)methyl]amino}-1H-1,2,4-triazol-3-yl)phenyl]propanamide, Tyrosine-protein kinase BTK | 著者 | Wang, Y.L, Sun, Y.Z, Cao, R, Liu, D, Xie, Y.T, Li, L, Qi, X.B, Huang, N. | 登録日 | 2017-07-11 | 公開日 | 2018-05-23 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | 主引用文献 | In Silico Identification of a Novel Hinge-Binding Scaffold for Kinase Inhibitor Discovery. J. Med. Chem., 60, 2017
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5ZZ4
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![BU of 5zz4 by Molmil](/molmil-images/mine/5zz4) | Crystal structure of bruton's tyrosine kinase in complex with inhibitor 2e | 分子名称: | N-[3-(4-amino-6-{[4-(morpholine-4-carbonyl)phenyl]amino}-1,3,5-triazin-2-yl)-2-methylphenyl]-4-tert-butylbenzamide, Tyrosine-protein kinase BTK | 著者 | Kawahata, W, Asami, T, Irie, T, Kiyoi, T, Taniguchi, H, Asamitsu, Y, Inoue, T, Miyake, T, Sawa, M. | 登録日 | 2018-05-30 | 公開日 | 2018-09-26 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Design and Synthesis of Novel Amino-triazine Analogues as Selective Bruton's Tyrosine Kinase Inhibitors for Treatment of Rheumatoid Arthritis. J. Med. Chem., 61, 2018
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6W8I
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![BU of 6w8i by Molmil](/molmil-images/mine/6w8i) | Ternary complex structure - BTK cIAP compound 15 | 分子名称: | 14-{[(3S)-2-(N-methyl-L-alanyl-3-methyl-L-valyl)-3-{[(1R)-1,2,3,4-tetrahydronaphthalen-1-yl]carbamoyl}-1,2,3,4-tetrahydroisoquinolin-7-yl]oxy}-3,6,9,12-tetraoxatetradecan-1-yl (3R)-3-{5-amino-4-carbamoyl-3-[4-(2,4-difluorophenoxy)phenyl]-1H-pyrazol-1-yl}piperidine-1-carboxylate, Baculoviral IAP repeat-containing protein 2, Tyrosine-protein kinase BTK, ... | 著者 | Calabrese, M.F, Schiemer, J.S. | 登録日 | 2020-03-20 | 公開日 | 2020-11-18 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural Characterization of BTK:PROTAC:cIAP Ternary Complexes: From Snapshots to Ensembles Nat.Chem.Biol., 2020
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1AWW
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![BU of 1aww by Molmil](/molmil-images/mine/1aww) | SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, 42 STRUCTURES | 分子名称: | BRUTON'S TYROSINE KINASE | 著者 | Hansson, H, Mattsson, P.T, Allard, P, Haapaniemi, P, Vihinen, M, Smith, C.I.E, Hard, T. | 登録日 | 1997-10-06 | 公開日 | 1998-04-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the SH3 domain from Bruton's tyrosine kinase. Biochemistry, 37, 1998
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1QLY
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![BU of 1qly by Molmil](/molmil-images/mine/1qly) | NMR Study of the SH3 Domain From Bruton's Tyrosine Kinase, 20 Structures | 分子名称: | TYROSINE-PROTEIN KINASE BTK | 著者 | Tzeng, S.R, Lou, Y.C, Pai, M.T, Chen, C, Chen, S.H, Cheng, J.Y. | 登録日 | 1999-09-20 | 公開日 | 1999-12-14 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the Human Btk SH3 Domain Complexed with a Proline-Rich Peptide from P120Cbl J.Biomol.NMR, 16, 2000
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2GE9
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1AWX
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![BU of 1awx by Molmil](/molmil-images/mine/1awx) | SH3 DOMAIN FROM BRUTON'S TYROSINE KINASE, NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | BRUTON'S TYROSINE KINASE | 著者 | Hansson, H, Mattsson, P.T, Allard, P, Haapaniemi, P, Vihinen, M, Smith, C.I.E, Hard, T. | 登録日 | 1997-10-06 | 公開日 | 1998-04-08 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of the SH3 domain from Bruton's tyrosine kinase. Biochemistry, 37, 1998
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