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PDB: 54 件

4Q7G
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1.7 Angstrom Crystal Structure of leukotoxin LukD from Staphylococcus aureus.
分子名称: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Leucotoxin LukDv
著者Minasov, G, Nocadello, S, Shuvalova, L, Shatsman, S, Kwon, K, Bagnoli, F, Falugi, F, Bottomley, M, Grandi, G, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2014-04-24
公開日2014-05-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structures of the components of the Staphylococcus aureus leukotoxin ED.
Acta Crystallogr D Struct Biol, 72, 2016
4IYC
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Structure of the T244A mutant of the PANTON-VALENTINE LEUCOCIDIN component from STAPHYLOCOCCUS AUREUS
分子名称: LukS-PV
著者Maveyraud, L, Guerin, F, Lavnetie, B.J, Prevost, G, Mourey, L.
登録日2013-01-28
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4J0O
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Structure of the Y246A Mutant of the PANTON-VALENTINE LEUCOCIDIN S Component from STAPHYLOCOCCUS AUREUS
分子名称: LukS-PV
著者Maveyraud, L, Laventie, B.J, Prevost, G, Mourey, L.
登録日2013-01-31
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4IYT
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Structure Of The Y184A Mutant Of The PANTON-VALENTINE LEUCOCIDIN S Component From STAPHYLOCOCCUS AUREUS
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, LukS-PV
著者Guerin, F, Laventie, B.J, Prevost, G, Mourey, L, Maveyraud, L.
登録日2013-01-29
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4IYA
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Structure of the Y250A mutant of the PANTON-VALENTINE LEUCOCIDIN S component from STAPHYLOCOCCUS AUREUS
分子名称: 1,2-ETHANEDIOL, CITRATE ANION, LukS-PV
著者Maveyraud, L, Guerin, F, Laventie, B.J, Prevost, G, Mourey, L.
登録日2013-01-28
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
4IZL
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Structure Of The N248A Mutant of the PANTON-VALENTINE LEUCOCIDIN S Component from STAPHYLOCOCCUS AUREUS
分子名称: LukS-PV
著者Maveyraud, L, Laventie, B.J, Prevost, G, Mourey, L.
登録日2013-01-30
公開日2014-01-29
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Residues essential for panton-valentine leukocidin s component binding to its cell receptor suggest both plasticity and adaptability in its interaction surface
Plos One, 9, 2014
3LKF
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LEUKOCIDIN F (HLGB) FROM STAPHYLOCOCCUS AUREUS WITH PHOSPHOCHOLINE BOUND
分子名称: LEUKOCIDIN F SUBUNIT, PHOSPHOCHOLINE
著者Olson, R, Nariya, H, Yokota, K, Kamio, Y, Gouaux, J.E.
登録日1998-07-28
公開日1999-07-28
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structure of staphylococcal LukF delineates conformational changes accompanying formation of a transmembrane channel.
Nat.Struct.Biol., 6, 1999
7P8X
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Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a doubly sulfated CCR2 N-terminal peptide
分子名称: C-C chemokine receptor type 2, IMIDAZOLE, Leucotoxin LukEv, ...
著者Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C.
登録日2021-07-23
公開日2022-04-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P8U
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Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with p-cresyl sulfate
分子名称: (4-methylphenyl) hydrogen sulfate, DI(HYDROXYETHYL)ETHER, IMIDAZOLE, ...
著者Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C.
登録日2021-07-23
公開日2022-04-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P93
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Crystal Structure of leukotoxin LukE from Staphylococcus aureus in complex with a sulfated ACKR1 N-terminal peptide
分子名称: Atypical chemokine receptor 1, Leucotoxin LukEv
著者Lambey, P, Hoh, F, Peysson, F, Granier, S, Leyrat, C.
登録日2021-07-23
公開日2022-04-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P8S
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Crystal Structure of leukotoxin LukE from Staphylococcus aureus at 1.9 Angstrom resolution
分子名称: (CARBAMOYLMETHYL-CARBOXYMETHYL-AMINO)-ACETIC ACID, HEXAETHYLENE GLYCOL, Leucotoxin LukEv, ...
著者Lambey, P, Hoh, F, Granier, S, Leyrat, C.
登録日2021-07-23
公開日2022-04-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
7P8T
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Crystal Structure of leukotoxin LukE from Staphylococcus aureus at 1.5 Angstrom resolution
分子名称: CHLORIDE ION, Leucotoxin LukEv
著者Lambey, P, Hoh, F, Granier, S, Leyrat, C.
登録日2021-07-23
公開日2022-04-06
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.459 Å)
主引用文献Structural insights into recognition of chemokine receptors by Staphylococcus aureus leukotoxins.
Elife, 11, 2022
3M4D
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Crystal structure of the M113N mutant of alpha-hemolysin
分子名称: Alpha-hemolysin
著者Montoya, M, Gouaux, E.
登録日2010-03-10
公開日2010-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M3R
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Crystal structure of the M113F alpha-hemolysin mutant complexed with beta-cyclodextrin
分子名称: Alpha-hemolysin, Cycloheptakis-(1-4)-(alpha-D-glucopyranose)
著者Montoya, M, Gouaux, E.
登録日2010-03-09
公開日2010-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M2L
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Crystal structure of the M113F mutant of alpha-hemolysin
分子名称: Alpha-hemolysin
著者Montoya, M, Gouaux, E.
登録日2010-03-07
公開日2010-05-12
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
3M4E
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BU of 3m4e by Molmil
Crystal structure of the M113N mutant of alpha-hemolysin bound to beta-cyclodextrin
分子名称: Alpha-hemolysin, Cycloheptakis-(1-4)-(alpha-D-glucopyranose)
著者Montoya, M, Gouaux, E.
登録日2010-03-10
公開日2010-05-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Molecular bases of cyclodextrin adapter interactions with engineered protein nanopores.
Proc.Natl.Acad.Sci.USA, 107, 2010
6U3F
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Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
分子名称: Panton-Valentine Leucocidin F, SULFATE ION, fos-choline-14
著者Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M.
登録日2019-08-21
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
6U2S
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Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
分子名称: Bi-component leukocidin LukED subunit D, fos-choline-14
著者Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M.
登録日2019-08-20
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
6U33
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Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
分子名称: Bi-component leukocidin LukED subunit D, NICKEL (II) ION
著者Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M.
登録日2019-08-21
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
6U3T
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Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
分子名称: Alpha-hemolysin, SULFATE ION, fos-choline-14
著者Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M.
登録日2019-08-22
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.79 Å)
主引用文献Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
6U4P
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Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
分子名称: Alpha-hemolysin, SULFATE ION, fos-choline-14
著者Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M.
登録日2019-08-26
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.49 Å)
主引用文献Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
6U3Y
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Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
分子名称: ACETATE ION, Gamma-hemolysin subunit A, Panton-Valentine Leucocidin F, ...
著者Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M.
登録日2019-08-22
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.04 Å)
主引用文献Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
6U49
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Structure-based discovery of a novel small-molecule inhibitor of methicillin-resistant S. aureus
分子名称: Alpha-hemolysin, SULFATE ION, fos-choline-14
著者Liu, J, Kozhaya, L, Torres, V.J, Unutmaz, D, Lu, M.
登録日2019-08-23
公開日2020-03-25
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.35 Å)
主引用文献Structure-based discovery of a small-molecule inhibitor of methicillin-resistantStaphylococcus aureusvirulence.
J.Biol.Chem., 295, 2020
7YL9
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Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
分子名称: Hemolysin
著者Mondal, A.K, Sengupta, N, Singh, M, Biswas, R, Lata, K, Lahiri, I, Dutta, S, Chattopadhyay, K.
登録日2022-07-25
公開日2022-08-31
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Cryo-EM structure of complete transmembrane channel E289A mutant Vibrio cholerae Cytolysin
J.Biol.Chem.
1XEZ
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Crystal Structure Of The Vibrio Cholerae Cytolysin (HlyA) Pro-Toxin With Octylglucoside Bound
分子名称: hemolysin, octyl beta-D-glucopyranoside
著者Olson, R, Gouaux, E.
登録日2004-09-13
公開日2005-06-14
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal Structure of the Vibrio cholerae Cytolysin (VCC) Pro-toxin and its Assembly into a Heptameric Transmembrane Pore
J.Mol.Biol., 350, 2005

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