6KOP
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6KQE
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![BU of 6kqe by Molmil](/molmil-images/mine/6kqe) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 4 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQD
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![BU of 6kqd by Molmil](/molmil-images/mine/6kqd) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 3 nt | 分子名称: | 2'-DEOXYGUANOSINE-5'-MONOPHOSPHATE, DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*CP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (3.3 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQM
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![BU of 6kqm by Molmil](/molmil-images/mine/6kqm) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 5 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.197 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KOQ
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6KQG
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![BU of 6kqg by Molmil](/molmil-images/mine/6kqg) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 6 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.783 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQL
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![BU of 6kql by Molmil](/molmil-images/mine/6kql) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 4 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQH
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![BU of 6kqh by Molmil](/molmil-images/mine/6kqh) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 7 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQN
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![BU of 6kqn by Molmil](/molmil-images/mine/6kqn) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 6 nt | 分子名称: | DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.489 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KON
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6LDI
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![BU of 6ldi by Molmil](/molmil-images/mine/6ldi) | |
6KOO
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6KQF
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![BU of 6kqf by Molmil](/molmil-images/mine/6kqf) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6L74
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![BU of 6l74 by Molmil](/molmil-images/mine/6l74) | Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 2 nt | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-10-31 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6M7J
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![BU of 6m7j by Molmil](/molmil-images/mine/6m7j) | Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin | 分子名称: | DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2018-08-20 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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6LTS
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6N62
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![BU of 6n62 by Molmil](/molmil-images/mine/6n62) | Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-24 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.803 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6N4C
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![BU of 6n4c by Molmil](/molmil-images/mine/6n4c) | EM structure of the DNA wrapping in bacterial open transcription initiation complex | 分子名称: | DNA (94-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Florez-Ariza, A, Cassago, A, de Oliveira, P.S.L, Guerra, D.G, Portugal, R.V. | 登録日 | 2018-11-19 | 公開日 | 2020-05-27 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation Biorxiv, 2020
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6N61
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![BU of 6n61 by Molmil](/molmil-images/mine/6n61) | Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capistruin, ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-24 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.253 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6N57
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![BU of 6n57 by Molmil](/molmil-images/mine/6n57) | Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-21 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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6TYG
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![BU of 6tyg by Molmil](/molmil-images/mine/6tyg) | |
6TYE
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![BU of 6tye by Molmil](/molmil-images/mine/6tye) | |
6UTV
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![BU of 6utv by Molmil](/molmil-images/mine/6utv) | E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP, UTP, GTP, and ddATP for 150 seconds) | 分子名称: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UUA
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![BU of 6uua by Molmil](/molmil-images/mine/6uua) | E. coli sigma-S transcription initiation complex with a mismatching CTP ("Fresh" crystal soaked with CTP for 2 hours) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.002 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UU3
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![BU of 6uu3 by Molmil](/molmil-images/mine/6uu3) | E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.002 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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