6KQG
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 6 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.783 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQL
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 4 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.89 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQH
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 7 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6KQN
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 6 nt | 分子名称: | DNA (5'-D(*CP*CP*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-18 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.489 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6LDI
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6KQF
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-OH RNA of 5 nt | 分子名称: | DNA (5'-D(*CP*CP*T*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*GP*GP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*CP*AP*GP*G*)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-08-17 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6L74
| Thermus thermophilus initial transcription complex comprising sigma A and 5'-triphosphate RNA of 2 nt | 分子名称: | DNA (5'-D(*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*CP*GP*AP*G)-3'), DNA (5'-D(*TP*AP*TP*AP*AP*TP*GP*GP*GP*AP*GP*CP*TP*GP*TP*CP*AP*CP*GP*GP*AP*TP*GP*C)-3'), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Zhang, Y, Li, L, Ebright, R.H. | 登録日 | 2019-10-31 | 公開日 | 2020-03-11 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | RNA extension drives a stepwise displacement of an initiation-factor structural module in initial transcription. Proc.Natl.Acad.Sci.USA, 117, 2020
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6M7J
| Mycobacterium tuberculosis RNAP with RbpA/us fork and Corallopyronin | 分子名称: | DNA (26-MER), DNA (31-MER), DNA-directed RNA polymerase subunit alpha, ... | 著者 | Darst, S.A, Campbell, E.A, Boyaci Selcuk, H, Chen, J. | 登録日 | 2018-08-20 | 公開日 | 2018-11-21 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | 主引用文献 | Structures of an RNA polymerase promoter melting intermediate elucidate DNA unwinding. Nature, 565, 2019
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6N62
| Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-24 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.803 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6N4C
| EM structure of the DNA wrapping in bacterial open transcription initiation complex | 分子名称: | DNA (94-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Florez-Ariza, A, Cassago, A, de Oliveira, P.S.L, Guerra, D.G, Portugal, R.V. | 登録日 | 2018-11-19 | 公開日 | 2020-05-27 | 実験手法 | ELECTRON MICROSCOPY (17 Å) | 主引用文献 | Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation Biorxiv, 2020
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6N61
| Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capistruin, ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-24 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.253 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6LTS
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6N57
| Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-21 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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6N58
| Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation II | 分子名称: | CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-21 | 公開日 | 2020-02-26 | 最終更新日 | 2024-03-20 | 実験手法 | ELECTRON MICROSCOPY (3.78 Å) | 主引用文献 | E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation. Elife, 8, 2019
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6N60
| Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25) | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A. | 登録日 | 2018-11-23 | 公開日 | 2019-01-09 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.68 Å) | 主引用文献 | Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin. Proc. Natl. Acad. Sci. U.S.A., 116, 2019
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6KJ6
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6OMF
| CryoEM structure of SigmaS-transcription initiation complex with activator Crl | 分子名称: | DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ... | 著者 | Jaramillo Cartagena, A, Darst, S.A, Campbell, E.A. | 登録日 | 2019-04-18 | 公開日 | 2019-08-28 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.26 Å) | 主引用文献 | Structural basis for transcription activation by Crl through tethering of sigmaSand RNA polymerase. Proc.Natl.Acad.Sci.USA, 116, 2019
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6ONO
| Complex structure of WhiB1 and region 4 of SigA in C2221 space group | 分子名称: | DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ... | 著者 | Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M. | 登録日 | 2019-04-22 | 公開日 | 2019-11-27 | 最終更新日 | 2020-01-22 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis. Nucleic Acids Res., 48, 2020
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6ONU
| Complex structure of WhiB1 and region 4 of SigA in P21 space group. | 分子名称: | DI(HYDROXYETHYL)ETHER, IRON/SULFUR CLUSTER, RNA polymerase sigma factor SigA, ... | 著者 | Wan, T, Li, S.R, Beltran, D.G, Schacht, A, Becker, D.C, Zhang, L.M. | 登録日 | 2019-04-22 | 公開日 | 2019-11-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Structural basis of non-canonical transcriptional regulation by the sigma A-bound iron-sulfur protein WhiB1 in M. tuberculosis. Nucleic Acids Res., 48, 2020
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6OY7
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6OVY
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6OVR
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6UTV
| E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP, UTP, GTP, and ddATP for 150 seconds) | 分子名称: | DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.45 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UUA
| E. coli sigma-S transcription initiation complex with a mismatching CTP ("Fresh" crystal soaked with CTP for 2 hours) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.002 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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6UU3
| E. coli sigma-S transcription initiation complex with a 4-nt RNA and a CTP ("Old" crystal soaked with GTP, ATP, CTP, and ddTTP for 30 minutes) | 分子名称: | CYTIDINE-5'-TRIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ... | 著者 | Zuo, Y, De, S, Steitz, T.A. | 登録日 | 2019-10-30 | 公開日 | 2020-08-26 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (4.002 Å) | 主引用文献 | Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Iscience, 23, 2020
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