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PDB: 291 件
6PSS
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BU of 6pss by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5a) with TraR and mutant rpsT P2 promoter
分子名称: DNA (85-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2019-07-13
公開日2020-03-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
7CHW
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BU of 7chw by Molmil
Cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo)
分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Lin, W, Feng, Y.
登録日2020-07-06
公開日2020-08-12
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.58 Å)
主引用文献Structural basis for transcription inhibition by E. coli SspA
Nucleic Acids Res., 2020
6PSQ
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BU of 6psq by Molmil
Escherichia coli RNA polymerase closed complex (TRPc) with TraR and rpsT P2 promoter
分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2019-07-13
公開日2020-03-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PST
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BU of 6pst by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi1.5b) with TraR and mutant rpsT P2 promoter
分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2019-07-13
公開日2020-03-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3 Å)
主引用文献Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
6PSV
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BU of 6psv by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TpreRPo) with TraR and rpsT P2 promoter
分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2019-07-13
公開日2020-03-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020
7BEG
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BU of 7beg by Molmil
Structures of class I bacterial transcription complexes
分子名称: Class I pacrA promoter non-template DNA, Class I pacrA promoter template DNA, DNA-directed RNA polymerase subunit alpha, ...
著者Ye, F.Z, Hao, M, Zhang, X.D.
登録日2020-12-23
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
7BEF
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BU of 7bef by Molmil
Structures of class II bacterial transcription complexes
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Hao, M, Ye, F.Z, Zhang, X.D.
登録日2020-12-23
公開日2021-12-01
最終更新日2024-07-10
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structures of Class I and Class II Transcription Complexes Reveal the Molecular Basis of RamA-Dependent Transcription Activation.
Adv Sci, 9, 2022
7EH0
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BU of 7eh0 by Molmil
Thermus thermophilus RNA polymerase transcription initiation complex containing a template-strand purine at position TSS-2, UpA RNA primer and CMPcPP
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*TP*AP*AP*AP*G)-3'), ...
著者Li, L, Zhang, Y.
登録日2021-03-27
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.808 Å)
主引用文献Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
7EH2
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BU of 7eh2 by Molmil
Thermus thermophilus transcription initiation complex containing a template-strand pyrimidine at position TSS-2 and GpG RNA primer
分子名称: DNA (27-MER), DNA (5'-D(*CP*C*TP*GP*CP*AP*TP*CP*CP*GP*TP*GP*AP*GP*CP*CP*TP*AP*G)-3'), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2021-03-27
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (3.34 Å)
主引用文献Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
7EH1
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BU of 7eh1 by Molmil
Thermus thermophilus transcription initiation complex containing a template-strand purine at position TSS-2, GpG RNA primer, and CMPcPP
分子名称: 1,4-BUTANEDIOL, 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (27-MER), ...
著者Li, L, Zhang, Y.
登録日2021-03-27
公開日2021-07-14
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Promoter-sequence determinants and structural basis of primer-dependent transcription initiation in Escherichia coli .
Proc.Natl.Acad.Sci.USA, 118, 2021
7DY6
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BU of 7dy6 by Molmil
A refined cryo-EM structure of an Escherichia coli RNAP-promoter open complex (RPo) with SspA
分子名称: DNA (63-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Lin, W.
登録日2021-01-20
公開日2021-11-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (3.68 Å)
主引用文献A unique binding between SspA and RNAP beta' NTH across low-GC Gram-negative bacteria facilitates SspA-mediated transcription regulation.
Biochem.Biophys.Res.Commun., 583, 2021
7C17
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BU of 7c17 by Molmil
The cryo-EM structure of E. coli CueR transcription activation complex with fully duplex promoter DNA
分子名称: DNA (72-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2020-05-02
公開日2020-09-30
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.22 Å)
主引用文献CueR activates transcription through a DNA distortion mechanism.
Nat.Chem.Biol., 17, 2021
8TOE
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BU of 8toe by Molmil
Escherichia coli RNA polymerase unwinding intermediate (I1c) at the lambda PR promoter
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Saecker, R.M, Mueller, A.U.
登録日2023-08-03
公開日2024-07-03
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
Nat.Struct.Mol.Biol., 2024
8TO6
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BU of 8to6 by Molmil
Escherichia coli RNA polymerase unwinding intermediate (I1d) at the lambda PR promoter
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Saecker, R.M, Mueller, A.U.
登録日2023-08-02
公開日2024-07-03
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
Nat.Struct.Mol.Biol., 2024
8TOM
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BU of 8tom by Molmil
Escherichia coli RNA polymerase closed complex intermediate at the lambda PR promoter
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Saecker, R.M, Mueller, A.U.
登録日2023-08-03
公開日2024-07-03
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.1 Å)
主引用文献Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
Nat.Struct.Mol.Biol., 2024
8TO8
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BU of 8to8 by Molmil
Escherichia coli RNA polymerase unwinding intermediate (I1b) at the lambda PR promoter
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Saecker, R.M, Mueller, A.U.
登録日2023-08-03
公開日2024-07-03
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
Nat.Struct.Mol.Biol., 2024
8TO1
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BU of 8to1 by Molmil
Escherichia coli RNA polymerase unwinding intermediate (I1a) at the lambda PR promoter
分子名称: (3R,5S,7R,8R,9S,10S,12S,13R,14S,17R)-10,13-dimethyl-17-[(2R)-pentan-2-yl]-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthrene-3,7,12-triol, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Darst, S.A, Saecker, R.M, Mueller, A.U.
登録日2023-08-02
公開日2024-07-03
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (2.8 Å)
主引用文献Early intermediates in bacterial RNA polymerase promoter melting visualized by time-resolved cryo-electron microscopy.
Nat.Struct.Mol.Biol., 2024
4KI2
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BU of 4ki2 by Molmil
Crystallographic analysis of an RNA-polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA
分子名称: DNA (5'-D(*TP*GP*TP*AP*CP*AP*AP*TP*GP*GP*G)-3'), POTASSIUM ION, RNA polymerase sigma factor
著者Feklistov, A, Darst, S.A.
登録日2013-05-01
公開日2013-09-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystallographic analysis of an RNA polymerase sigma-subunit fragment complexed with -10 promoter element ssDNA: quadruplex formation as a possible tool for engineering crystal contacts in protein-ssDNA complexes.
Acta Crystallogr.,Sect.F, 69, 2013
8X6G
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BU of 8x6g by Molmil
Cryo-EM structure of Staphylococcus aureus sigB-dependent RNAP-promoter open complex
分子名称: DNA (70-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yuan, L, Xu, L, Liu, Q, Feng, Y.
登録日2023-11-21
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
8X6F
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BU of 8x6f by Molmil
Cryo-EM structure of Staphylococcus aureus sigA-dependent RNAP-promoter open complex
分子名称: DNA (71-mer), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yuan, L, Xu, L, Liu, Q, Feng, Y.
登録日2023-11-21
公開日2024-06-05
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural basis of promoter recognition by Staphylococcus aureus RNA polymerase.
Nat Commun, 15, 2024
8W8N
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BU of 8w8n by Molmil
Thermus thermophilus initiation transcription complex in the pre-translocated state
分子名称: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2023-09-04
公開日2024-07-24
実験手法X-RAY DIFFRACTION (2.693 Å)
主引用文献Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
8W8P
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BU of 8w8p by Molmil
Thermus thermophilus initiation transcription complex containing CMPcPP in the post-translocated state
分子名称: 5'-O-[(S)-hydroxy{[(S)-hydroxy(phosphonooxy)phosphoryl]methyl}phosphoryl]cytidine, DNA (21-MER), DNA (27-MER), ...
著者Li, L, Zhang, Y.
登録日2023-09-04
公開日2024-07-24
実験手法X-RAY DIFFRACTION (3.165 Å)
主引用文献Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
8W8O
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BU of 8w8o by Molmil
Thermus thermophilus initiation complex in the half-translocated state
分子名称: DNA (21-MER), DNA (27-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Li, L, Zhang, Y.
登録日2023-09-04
公開日2024-07-24
実験手法X-RAY DIFFRACTION (2.512 Å)
主引用文献Nanopore tweezers show fractional-nucleotide translocation in sequence-dependent pausing by RNA polymerase.
Proc.Natl.Acad.Sci.USA, 121, 2024
4LK1
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BU of 4lk1 by Molmil
Crystal Structure Analysis of the E.coli holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Bae, B, Darst, S.A.
登録日2013-07-05
公開日2013-11-13
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.8369 Å)
主引用文献Phage T7 Gp2 inhibition of Escherichia coli RNA polymerase involves misappropriation of sigma 70 domain 1.1.
Proc.Natl.Acad.Sci.USA, 110, 2013
8U3B
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BU of 8u3b by Molmil
Cryo-EM structure of E. coli NarL-transcription activation complex at 3.2A
分子名称: DNA (69-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Kompaniiets, D, Wang, D.
登録日2023-09-07
公開日2024-01-17
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (3.23 Å)
主引用文献Structural basis for transcription activation by the nitrate-responsive regulator NarL.
Nucleic Acids Res., 52, 2024

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件を2024-08-07に公開中

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