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PDB: 107 件

7MKE
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BU of 7mke by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 2)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKD
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BU of 7mkd by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR promoter DNA (class 1)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2021-10-13
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7MKI
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BU of 7mki by Molmil
Cryo-EM structure of Escherichia coli RNA polymerase bound to lambda PR (-5G to C) promoter DNA
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Saecker, R.M, Darst, S.A, Chen, J.
登録日2021-04-23
公開日2021-09-29
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Structural origins of Escherichia coli RNA polymerase open promoter complex stability.
Proc.Natl.Acad.Sci.USA, 118, 2021
7KHC
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BU of 7khc by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter closed complex
分子名称: CHAPSO, DNA (18 MER), DNA (63-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-20
公開日2020-10-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.14 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
7KHI
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BU of 7khi by Molmil
Escherichia coli RNA polymerase and rrnBP1 promoter complex with DksA/ppGpp
分子名称: CHAPSO, DNA (28-MER), DNA (36-MER), ...
著者Shin, Y, Qayyum, M.Z, Murakami, K.S.
登録日2020-10-21
公開日2020-10-28
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.62 Å)
主引用文献Structural basis of ribosomal RNA transcription regulation.
Nat Commun, 12, 2021
6C9Y
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BU of 6c9y by Molmil
Cryo-EM structure of E. coli RNAP sigma70 holoenzyme
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yenool, D, Jiang, W, Murakami, K.S.
登録日2018-01-29
公開日2018-02-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.25 Å)
主引用文献Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation.
J. Biol. Chem., 293, 2018
7N4E
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Escherichia coli sigma 70-dependent paused transcription elongation complex
分子名称: 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Molodtsov, V, Su, M, Ebright, R.H.
登録日2021-06-04
公開日2022-06-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural and mechanistic basis of sigma-dependent transcriptional pausing.
Proc.Natl.Acad.Sci.USA, 119, 2022
6CUX
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BU of 6cux by Molmil
Escherichia coli RpoB S531L mutant RNA polymerase holoenzyme in complex with Kanglemycin A
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Murakami, K.S.
登録日2018-03-26
公開日2018-07-25
最終更新日2020-01-01
実験手法X-RAY DIFFRACTION (4.104 Å)
主引用文献Mode of Action of Kanglemycin A, an Ansamycin Natural Product that Is Active against Rifampicin-Resistant Mycobacterium tuberculosis.
Mol. Cell, 72, 2018
6BYU
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BU of 6byu by Molmil
X-ray crystal structure of Escherichia coli RNA polymerase (RpoB-H526Y) and ppApp complex
分子名称: (5R)-5-(6-amino-9H-purin-9-yl)-2-({[(S)-hydroxy(phosphonooxy)phosphoryl]oxy}methyl)-4-oxo-4,5-dihydrofuran-3-yl trihydrogen diphosphate, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Murakami, K.S, Molodtsov, V.
登録日2017-12-21
公開日2018-01-17
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.6 Å)
主引用文献Structure-function comparisons of (p)ppApp vs (p)ppGpp for Escherichia coli RNA polymerase binding sites and for rrnB P1 promoter regulatory responses in vitro.
Biochim. Biophys. Acta, 1861, 2018
6CA0
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BU of 6ca0 by Molmil
Cryo-EM structure of E. coli RNAP sigma70 open complex
分子名称: DNA (35-MER), DNA (45-MER), DNA (5'-D(P*GP*CP*CP*GP*CP*GP*TP*CP*AP*GP*A)-3'), ...
著者Narayanan, A, Vago, F, Li, K, Qayyum, M.Z, Yernool, D, Jiang, W, Murakami, K.S.
登録日2018-01-29
公開日2018-02-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (5.75 Å)
主引用文献Cryo-EM structure ofEscherichia colisigma70RNA polymerase and promoter DNA complex revealed a role of sigma non-conserved region during the open complex formation.
J. Biol. Chem., 293, 2018
7L7B
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BU of 7l7b by Molmil
Clostridioides difficile RNAP with fidaxomicin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Boyaci, H, Campbell, E.A, Darst, S.A, Chen, J.
登録日2020-12-28
公開日2022-02-02
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.26 Å)
主引用文献Basis of narrow-spectrum activity of fidaxomicin on Clostridioides difficile.
Nature, 604, 2022
6N62
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BU of 6n62 by Molmil
Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A.
登録日2018-11-24
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.803 Å)
主引用文献Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N4C
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BU of 6n4c by Molmil
EM structure of the DNA wrapping in bacterial open transcription initiation complex
分子名称: DNA (94-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Florez-Ariza, A, Cassago, A, de Oliveira, P.S.L, Guerra, D.G, Portugal, R.V.
登録日2018-11-19
公開日2020-05-27
実験手法ELECTRON MICROSCOPY (17 Å)
主引用文献Interactions of Upstream and Downstream Promoter Regions with RNA Polymerase are Energetically Coupled and a Target of Regulation in Transcription Initiation
Biorxiv, 2020
6N61
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BU of 6n61 by Molmil
Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Capistruin
分子名称: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Capistruin, ...
著者Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A.
登録日2018-11-24
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.253 Å)
主引用文献Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N57
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BU of 6n57 by Molmil
Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation I
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2018-11-21
公開日2020-02-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.7 Å)
主引用文献E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
6N60
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BU of 6n60 by Molmil
Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA and Microcin J25 (MccJ25)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A.
登録日2018-11-23
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.68 Å)
主引用文献Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
6N58
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BU of 6n58 by Molmil
Cryo-EM structure of Escherichia coli RNAP polymerase bound with TraR in conformation II
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2018-11-21
公開日2020-02-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.78 Å)
主引用文献E. coliTraR allosterically regulates transcription initiation by altering RNA polymerase conformation.
Elife, 8, 2019
7CKQ
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BU of 7ckq by Molmil
The cryo-EM structure of B. subtilis BmrR transcription activation complex
分子名称: DNA (50-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Fang, C.L, Zhang, Y.
登録日2020-07-18
公開日2020-12-16
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献The bacterial multidrug resistance regulator BmrR distorts promoter DNA to activate transcription.
Nat Commun, 11, 2020
6XLM
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BU of 6xlm by Molmil
Cryo-EM structure of E.coli RNAP-DNA elongation complex 1 (RDe1) in EcmrR-dependent transcription
分子名称: 9-nt RNA transcript, CHAPSO, DNA-directed RNA polymerase subunit alpha, ...
著者Yang, Y, Liu, C, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XH7
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BU of 6xh7 by Molmil
CueR-TAC without RNA
分子名称: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W, Yang, Y.
登録日2020-06-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021
6XLL
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BU of 6xll by Molmil
Cryo-EM structure of E. coli RNAP-promoter initial transcribing complex with 5-nt RNA transcript (RPitc-5nt)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yang, Y, Liu, C, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XL9
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BU of 6xl9 by Molmil
Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 3-nt RNA transcript (EcmrR-RPitc-3nt)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Yang, Y, Liu, C, Shi, W, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XLJ
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BU of 6xlj by Molmil
Cryo-EM structure of EcmrR-RNAP-promoter initial transcribing complex with 4-nt RNA transcript (EcmrR-RPitc-4nt)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yang, Y, Liu, C, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XL5
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BU of 6xl5 by Molmil
Cryo-EM structure of EcmrR-RNAP-promoter open complex (EcmrR-RPo)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Yang, Y, Liu, C, Liu, B.
登録日2020-06-28
公開日2021-04-07
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural visualization of transcription activated by a multidrug-sensing MerR family regulator.
Nat Commun, 12, 2021
6XH8
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BU of 6xh8 by Molmil
CueR-transcription activation complex with RNA transcript
分子名称: COPPER (II) ION, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Liu, B, Shi, W, Yang, Y.
登録日2020-06-18
公開日2021-04-14
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Structural basis of copper-efflux-regulator-dependent transcription activation.
Iscience, 24, 2021

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件を2024-06-12に公開中

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