6R7Q
 
 | | Structure of XBP1u-paused ribosome nascent chain complex with Sec61. | | 分子名称: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | | 著者 | Shanmuganathan, V, Cheng, J, Braunger, K, Berninghausen, O, Beatrix, B, Beckmann, R. | | 登録日 | 2019-03-29 | | 公開日 | 2019-07-10 | | 最終更新日 | 2024-05-22 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Structural and mutational analysis of the ribosome-arresting human XBP1u.
Elife, 8, 2019
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6W6L
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3DKN
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7AFT
 | | Cryo-EM structure of the signal sequence-engaged post-translational Sec translocon | | 分子名称: | Mating factor alpha-1,Mating factor alpha-1, Protein translocation protein SEC63, Protein transport protein SBH1, ... | | 著者 | Weng, T.-H, Beatrix, B, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R. | | 登録日 | 2020-09-20 | | 公開日 | 2020-12-02 | | 最終更新日 | 2024-05-01 | | 実験手法 | ELECTRON MICROSCOPY (4.4 Å) | | 主引用文献 | Architecture of the active post-translational Sec translocon.
Embo J., 40, 2021
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5A6U
 | | Native mammalian ribosome-bound Sec61 protein-conducting channel in the 'non-inserting' state | | 分子名称: | SEC61A, SEC61B, SEC61G | | 著者 | Pfeffer, S, Burbaum, L, Unverdorben, P, Pech, M, Chen, Y, Zimmermann, R, Beckmann, R, Foerster, F. | | 登録日 | 2015-07-01 | | 公開日 | 2015-10-07 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structure of the Native Sec61 Protein-Conducting Channel.
Nat.Commun., 6, 2015
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4V4N
 | | Structure of the Methanococcus jannaschii ribosome-SecYEBeta channel complex | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein L7AE, ... | | 著者 | Menetret, J.F, Park, E, Gumbart, J.C, Ludtke, S.J, Li, W, Whynot, A, Rapoport, T.A, Akey, C.W. | | 登録日 | 2013-06-17 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (9 Å) | | 主引用文献 | Structure of the SecY channel during initiation of protein translocation.
Nature, 506, 2013
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4V7I
 | | Ribosome-SecY complex. | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Gumbart, J.C, Trabuco, L.G, Schreiner, E, Villa, E, Schulten, K. | | 登録日 | 2009-10-21 | | 公開日 | 2014-07-09 | | 最終更新日 | 2024-02-28 | | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | | 主引用文献 | Regulation of the protein-conducting channel by a bound ribosome.
Structure, 17, 2009
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7TUT
 | | Structure of the rabbit 80S ribosome stalled on a 4-TMD Rhodopsin intermediate in complex with the multipass translocon | | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | | 登録日 | 2022-02-03 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-06-12 | | 実験手法 | ELECTRON MICROSCOPY (3.88 Å) | | 主引用文献 | Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
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8B6L
 | | Subtomogram average of the human Sec61-TRAP-OSTA-translocon | | 分子名称: | Dolichyl-diphosphooligosaccharide--protein glycosyltransferase 48 kDa subunit, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1, Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 2, ... | | 著者 | Gemmer, M, Fedry, J.M.M, Forster, F.G. | | 登録日 | 2022-09-27 | | 公開日 | 2022-12-07 | | 最終更新日 | 2023-02-08 | | 実験手法 | ELECTRON MICROSCOPY (7.6 Å) | | 主引用文献 | Visualization of translation and protein biogenesis at the ER membrane.
Nature, 614, 2023
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8BTK
 | | Structure of the TRAP complex with the Sec translocon and a translating ribosome | | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S11, ... | | 著者 | Jaskolowski, M, Jomaa, A, Gamerdinger, M, Shrestha, S, Leibundgut, M, Deuerling, E, Ban, N. | | 登録日 | 2022-11-29 | | 公開日 | 2023-05-24 | | 最終更新日 | 2024-04-24 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | Molecular basis of the TRAP complex function in ER protein biogenesis.
Nat.Struct.Mol.Biol., 30, 2023
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7TM3
 | | Structure of the rabbit 80S ribosome stalled on a 2-TMD Rhodopsin intermediate in complex with the multipass translocon | | 分子名称: | 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Kim, M.K, Lewis, A.J.O, Keenan, R.J, Hegde, R.S. | | 登録日 | 2022-01-19 | | 公開日 | 2022-10-19 | | 最終更新日 | 2024-06-05 | | 実験手法 | ELECTRON MICROSCOPY (3.25 Å) | | 主引用文献 | Mechanism of an intramembrane chaperone for multipass membrane proteins.
Nature, 611, 2022
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3BO0
 | | Ribosome-SecY complex | | 分子名称: | 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ... | | 著者 | Akey, C.W, Menetret, J.F. | | 登録日 | 2007-12-15 | | 公開日 | 2008-12-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | | 主引用文献 | Ribosome binding of a single copy of the SecY complex: implications for protein translocation
Mol.Cell, 28, 2007
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3BO1
 | | Ribosome-SecY complex | | 分子名称: | 23S RIBOSOMAL RNA, PREPROTEIN TRANSLOCASE SecE SUBUNIT, PREPROTEIN TRANSLOCASE SecY SUBUNIT, ... | | 著者 | Akey, C.W, Menetret, J.F. | | 登録日 | 2007-12-15 | | 公開日 | 2008-12-09 | | 最終更新日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (9.6 Å) | | 主引用文献 | Ribosome binding of a single copy of the SecY complex: implications for protein translocation
Mol.Cell, 28, 2007
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6ND1
 | | CryoEM structure of the Sec Complex from yeast | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Wu, X, Cabanos, C, Rapoport, T.A. | | 登録日 | 2018-12-13 | | 公開日 | 2019-01-09 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | | 主引用文献 | Structure of the post-translational protein translocation machinery of the ER membrane.
Nature, 566, 2019
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8OJ8
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 1 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-24 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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8OJ0
 | | 60S ribosomal subunit bound to the E3-UFM1 complex - state 2 (native) | | 分子名称: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | | 著者 | Penchev, I, DaRosa, P.A, Becker, T, Beckmann, R, Kopito, R. | | 登録日 | 2023-03-23 | | 公開日 | 2024-02-21 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | UFM1 E3 ligase promotes recycling of 60S ribosomal subunits from the ER.
Nature, 627, 2024
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6N3Q
 | | Cryo-EM structure of the yeast Sec complex | | 分子名称: | Protein translocation protein SEC63, Protein transport protein SBH1, Protein transport protein SEC61, ... | | 著者 | Park, E, Itskanov, S. | | 登録日 | 2018-11-16 | | 公開日 | 2018-12-19 | | 最終更新日 | 2024-03-20 | | 実験手法 | ELECTRON MICROSCOPY (3.68 Å) | | 主引用文献 | Structure of the posttranslational Sec protein-translocation channel complex from yeast.
Science, 363, 2019
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1RHZ
 | | The structure of a protein conducting channel | | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | 登録日 | 2003-11-15 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | X-ray structure of a protein-conducting channel.
Nature, 427, 2004
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1RH5
 | | The structure of a protein conducting channel | | 分子名称: | Preprotein translocase secE subunit, Preprotein translocase secY subunit, SecBeta | | 著者 | van den Berg, B, Clemons Jr, W.M, Collinson, I, Modis, Y, Hartmann, E, Harrison, S.C, Rapoport, T.A. | | 登録日 | 2003-11-13 | | 公開日 | 2004-01-06 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | X-ray structure of a protein-conducting channel
Nature, 427, 2004
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4CG5
 | | Cryo-EM of the Sec61-complex bound to the 80S ribosome translating a secretory substrate | | 分子名称: | PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT ALPHA ISOFORM 1, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT BETA, PROTEIN TRANSPORT PROTEIN SEC61 SUBUNIT GAMMA | | 著者 | Gogala, M, Becker, T, Beatrix, B, Barrio-Garcia, C, Berninghausen, O, Beckmann, R. | | 登録日 | 2013-11-21 | | 公開日 | 2014-02-05 | | 最終更新日 | 2024-05-08 | | 実験手法 | ELECTRON MICROSCOPY (7.4 Å) | | 主引用文献 | Structures of the Sec61 Complex Engaged in Nascent Peptide Translocation or Membrane Insertion.
Nature, 506, 2014
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6FTI
 | | Cryo-EM Structure of the Mammalian Oligosaccharyltransferase Bound to Sec61 and the Programmed 80S Ribosome | | 分子名称: | 28S rRNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | | 著者 | Braunger, K, Becker, T, Beckmann, R. | | 登録日 | 2018-02-22 | | 公開日 | 2018-03-21 | | 最終更新日 | 2020-07-29 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structural basis for coupling protein transport and N-glycosylation at the mammalian endoplasmic reticulum.
Science, 360, 2018
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8RJD
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8RJC
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8RJB
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6FTG
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