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PDB: 40 件
4HPF
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Structure of the human SLO3 gating ring
分子名称: Potassium channel subfamily U member 1
著者Leonetti, M.D, Yuan, P, MacKinnon, R.
登録日2012-10-23
公開日2012-11-07
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Functional and structural analysis of the human SLO3 pH- and voltage-gated K+ channel.
Proc.Natl.Acad.Sci.USA, 109, 2012
3U6N
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Open Structure of the BK channel Gating Ring
分子名称: CALCIUM ION, High-Conductance Ca2+-Activated K+ Channel protein
著者Yuan, P, MacKinnon, R.
登録日2011-10-12
公開日2011-12-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.61 Å)
主引用文献Open structure of the Ca(2+) gating ring in the high-conductance Ca(2+)-activated K(+) channel.
Nature, 481, 2011
3NAF
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Structure of the Intracellular Gating Ring from the Human High-conductance Ca2+ gated K+ Channel (BK Channel)
分子名称: Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1,Calcium-activated potassium channel subunit alpha-1
著者Wu, Y, Yang, Y, Ye, S, Jiang, Y.
登録日2010-06-01
公開日2010-06-30
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of the gating ring from the human large-conductance Ca(2+)-gated K(+) channel.
Nature, 466, 2010
3MT5
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Crystal Structure of the Human BK Gating Apparatus
分子名称: CALCIUM ION, Potassium large conductance calcium-activated channel, subfamily M, ...
著者Yuan, P, MacKinnon, R.
登録日2010-04-30
公開日2010-06-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution.
Science, 329, 2010
5U76
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Chicken Slo2.2 in a closed conformation vitrified in the presence of 300 mM NaCl
分子名称: Potassium channel subfamily T member 1
著者Hite, R.K, MacKinnon, R.
登録日2016-12-11
公開日2017-02-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel.
Cell, 168, 2017
5A6E
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Cryo-EM structure of the Slo2.2 Na-activated K channel
分子名称: GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, ...
著者Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R.
登録日2015-06-25
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
5A6F
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Cryo-EM structure of the Slo2.2 Na-activated K channel
分子名称: GATING RING OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, RCK2 ELABORATION OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1
著者Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R.
登録日2015-06-25
公開日2015-10-14
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
5U70
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Chicken Slo2.2 in an open conformation vitrified in the presence of 300 mM NaCl
分子名称: Potassium channel subfamily T member 1
著者Hite, R.K, MacKinnon, R.
登録日2016-12-09
公開日2017-02-08
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.76 Å)
主引用文献Structural Titration of Slo2.2, a Na(+)-Dependent K(+) Channel.
Cell, 168, 2017
6V5A
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Crystal structure of the human BK channel gating ring L390P mutant
分子名称: CALCIUM ION, Calcium-activated potassium channel subunit alpha-1, SULFATE ION
著者Deng, Z, Yuan, P.
登録日2019-12-03
公開日2020-07-01
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Coupling of Ca2+and voltage activation in BK channels through the alpha B helix/voltage sensor interface.
Proc.Natl.Acad.Sci.USA, 117, 2020
8HKK
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ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.84 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HIR
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BU of 8hir by Molmil
potassium channels
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-21
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (3.18 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKQ
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ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, SODIUM ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.9 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKF
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ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
著者Jiang, D.H, Zhang, Z.T.
登録日2022-11-25
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.66 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HKM
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ion channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION, ...
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-27
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.95 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
8HK6
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BU of 8hk6 by Molmil
potassium channel
分子名称: POTASSIUM ION, Potassium channel subfamily T member 1, ZINC ION
著者Jiang, D.H, Zhang, J.T.
登録日2022-11-25
公開日2023-08-16
実験手法ELECTRON MICROSCOPY (2.64 Å)
主引用文献Structural basis of human Slo2.2 channel gating and modulation.
Cell Rep, 42, 2023
6ND0
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BU of 6nd0 by Molmil
human BK channel reconstituted into liposomes
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Wang, L, Tonggu, L.
登録日2018-12-13
公開日2020-06-17
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Broken symmetry in the human BK channel
To Be Published
8S3E
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Structure of rabbit Slo1 in complex with gamma1/LRRC26
分子名称: (4S,7R)-4-HYDROXY-N,N,N-TRIMETHYL-9-OXO-7-[(PALMITOYLOXY)METHYL]-3,5,8-TRIOXA-4-PHOSPHAHEXACOSAN-1-AMINIUM 4-OXIDE, CALCIUM ION, CHOLESTEROL, ...
著者Redhardt, M, Raunser, S, Raisch, T.
登録日2024-02-20
公開日2024-04-10
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Cryo-EM structure of the Slo1 potassium channel with the auxiliary gamma 1 subunit suggests a mechanism for depolarization-independent activation.
Febs Lett., 598, 2024
8Z3S
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BU of 8z3s by Molmil
Activation mechanism and novel binding site of the BKCa channel activator CTIBD
分子名称: 4-[4-(4-chlorophenyl)-3-(trifluoromethyl)-1,2-oxazol-5-yl]benzene-1,3-diol, CALCIUM ION, CHOLESTEROL HEMISUCCINATE, ...
著者Lee, N, Kim, S, Jo, H, Lee, N.Y, Jin, M.S, Park, C.S.
登録日2024-04-16
公開日2024-07-31
最終更新日2024-09-11
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Activation mechanism and novel binding sites of the BK Ca channel activator CTIBD.
Life Sci Alliance, 7, 2024
7RK6
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Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-22
公開日2022-06-22
最終更新日2024-11-06
実験手法ELECTRON MICROSCOPY (2.91 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 0 mM Ba2+ at 2.91 A
To Be Published
7RJT
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Aplysia Slo1 with Barium
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, BARIUM ION, BK channel, ...
著者Zhu, J, Srivastava, S, Cachau, R, Holmgren, M.
登録日2021-07-21
公開日2022-06-22
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (2.93 Å)
主引用文献CryoEM structure of Aplysia Slo1 with 10 mM Ba2+ at 2.93 A
To Be Published
5TJ6
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BU of 5tj6 by Molmil
Ca2+ bound aplysia Slo1
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, CALCIUM ION, High conductance calcium-activated potassium channel, ...
著者MacKinnon, R, Tao, X, Hite, R.K.
登録日2016-10-03
公開日2016-12-14
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Cryo-EM structure of the open high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
5TJI
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Ca2+ bound aplysia Slo1
分子名称: (1R)-2-{[(S)-{[(2S)-2,3-dihydroxypropyl]oxy}(hydroxy)phosphoryl]oxy}-1-[(hexadecanoyloxy)methyl]ethyl (9Z)-octadec-9-enoate, High conductance calcium-activated potassium channel
著者MacKinnon, R, Tao, X, Hite, R.K.
登録日2016-10-04
公開日2016-12-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for gating the high-conductance Ca(2+)-activated K(+) channel.
Nature, 541, 2017
8GHF
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cryo-EM structure of hSlo1 in plasma membrane vesicles
分子名称: (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CALCIUM ION, CHOLESTEROL, ...
著者Tao, X, Zhao, C, MacKinnon, R.
登録日2023-03-10
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Membrane protein isolation and structure determination in cell-derived membrane vesicles.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GHG
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Cryo-EM structure of hSlo1 in digitonin, Ca2+-free and EDTA-free
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Tao, X, Zhao, C, MacKinnon, R.
登録日2023-03-10
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Membrane protein isolation and structure determination in cell-derived membrane vesicles.
Proc.Natl.Acad.Sci.USA, 120, 2023
8GH9
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Cryo-EM structure of hSlo1 in total membrane vesicles
分子名称: Calcium-activated potassium channel subunit alpha-1
著者Tao, X, Zhao, C, MacKinnon, R.
登録日2023-03-09
公開日2023-05-10
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Membrane protein isolation and structure determination in cell-derived membrane vesicles.
Proc.Natl.Acad.Sci.USA, 120, 2023

 

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