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PDB: 156 件

6PCD
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Crystal structure of beta-ketoadipyl-CoA thiolase mutant (C90S-H356A) in complex Octanoyl coenzyme A
分子名称: Beta-ketoadipyl-CoA thiolase, CHLORIDE ION, COENZYME A, ...
著者Sukritee, B, Panjikar, S.
登録日2019-06-17
公開日2020-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.37 Å)
主引用文献Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase.
J Struct Biol X, 4, 2020
1AFW
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THE 1.8 ANGSTROM CRYSTAL STRUCTURE OF THE DIMERIC PEROXISOMAL THIOLASE OF SACCHAROMYCES CEREVISIAE
分子名称: (4R)-2-METHYLPENTANE-2,4-DIOL, 3-KETOACETYL-COA THIOLASE
著者Mathieu, M, Wierenga, R.K.
登録日1997-03-15
公開日1997-06-16
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism.
J.Mol.Biol., 273, 1997
4DD5
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Biosynthetic Thiolase (ThlA1) from Clostridium difficile
分子名称: Acetyl-CoA acetyltransferase
著者Filippova, E.V, Wawrzak, Z, Kudritska, M, Edwards, A, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-01-18
公開日2012-02-01
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.25 Å)
主引用文献Biosynthetic Thiolase (ThlA1) from Clostridium difficile
To be Published
3GOA
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BU of 3goa by Molmil
Crystal structure of the Salmonella typhimurium FadA 3-ketoacyl-CoA thiolase
分子名称: 3-ketoacyl-CoA thiolase, CALCIUM ION, CHLORIDE ION, ...
著者Anderson, S.M, Skarina, T, Onopriyenko, O, Wawrzak, Z, Papazisi, L, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2009-03-18
公開日2009-03-31
最終更新日2017-11-01
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献

5XYJ
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Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL
著者Zhou, P.F.
登録日2017-07-08
公開日2018-07-11
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Purification,crystallization and structural analysis of cytoplastic acetoacetyl-CoA thiolase from Saccharomyces cerevisiae
To Be Published
7FEA
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PY14 in complex with Col-D
分子名称: (6~{R},7~{R},9~{E})-6,7-bis(oxidanyl)hexadeca-9,15-dien-11,13-diynoic acid, Acetyl-CoA C-acyltransferase
著者Lin, C.C, Ko, T.P, Huang, K.F, Yang, Y.L.
登録日2021-07-19
公開日2022-07-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Integrated omics approach to unveil antifungal bacterial polyynes as acetyl-CoA acetyltransferase inhibitors.
Commun Biol, 5, 2022
4E1L
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Crystal structure of Acetoacetyl-CoA thiolase (thlA2) from Clostridium difficile
分子名称: Acetoacetyl-CoA thiolase 2, IODIDE ION
著者Anderson, S.M, Wawrzak, Z, Kudritska, M, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2012-03-06
公開日2012-03-21
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献

8ECM
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Crystal Structure Analysis of Acetyl-CoA acetyltransferase from Firmicutes bacterium
分子名称: Acetyl-CoA acetyltransferase
著者Seo, H.S, Dhe-Paganon, S.
登録日2022-09-02
公開日2023-05-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.89 Å)
主引用文献Gut microbial metabolism of 5-ASA diminishes its clinical efficacy in inflammatory bowel disease.
Nat Med, 29, 2023
6PCA
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Crystal structure of beta-ketoadipyl-CoA thiolase
分子名称: ACETATE ION, Beta-ketoadipyl-CoA thiolase, CHLORIDE ION, ...
著者Sukritee, B, Panjikar, S.
登録日2019-06-17
公開日2020-05-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.81 Å)
主引用文献Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase.
J Struct Biol X, 4, 2020
1QFL
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BIOSYNTHETIC THIOLASE FROM ZOOGLOEA RAMIGERA IN COMPLEX WITH A REACTION INTERMEDIATE.
分子名称: COENZYME A, PROTEIN (ACETOACETYL-COA THIOLASE), SULFATE ION
著者Modis, Y, Wierenga, R.K.
登録日1999-04-12
公開日2000-04-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism.
Structure Fold.Des., 7, 1999
5LP7
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Crystal structure of 3-Ketoacyl-CoA Thiolase (MmgA) from Bacillus subtilis.
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL
著者Baker, G.E, Race, P.R.
登録日2016-08-11
公開日2016-08-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of 3-Ketoacyl-CoA Thiolase (MmgA) from Bacillus subtilis.
To Be Published
5ONC
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Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis is Controlled by a Redox-Sensitive Thiol Switch
分子名称: CHLORIDE ION, Steroid 3-ketoacyl-CoA thiolase
著者Schaefer, C, Kuper, J, Sampson, N.S, Kisker, C.
登録日2017-08-03
公開日2017-08-23
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Catabolism of the Cholesterol Side Chain in Mycobacterium tuberculosis Is Controlled by a Redox-Sensitive Thiol Switch.
ACS Infect Dis, 3, 2017
6PCB
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Crystal structure of beta-ketoadipyl-CoA thiolase mutant (H356A) in complex with COA
分子名称: Beta-ketoadipyl-CoA thiolase, CHLORIDE ION, COENZYME A, ...
著者Sukritee, B, Panjikar, S.
登録日2019-06-17
公開日2020-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.61 Å)
主引用文献Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase.
J Struct Biol X, 4, 2020
6PCC
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Crystal structure of beta-ketoadipyl-CoA thiolase mutant (H356A) in complex hexanoyl coenzyme A
分子名称: Beta-ketoadipyl-CoA thiolase, COENZYME A, GLYCEROL, ...
著者Sukritee, B, Panjikar, S.
登録日2019-06-17
公開日2020-05-27
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural basis for differentiation between two classes of thiolase: Degradative vs biosynthetic thiolase.
J Struct Biol X, 4, 2020
7CW4
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Acetyl-CoA acetyltransferase from Bacillus cereus ATCC 14579
分子名称: Acetyl-CoA acetyltransferase, GLYCEROL
著者Hong, J, Kim, K.J.
登録日2020-08-27
公開日2020-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Crystal structure of an acetyl-CoA acetyltransferase from PHB producing bacterium Bacillus cereus ATCC 14579.
Biochem.Biophys.Res.Commun., 533, 2020
3SS6
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BU of 3ss6 by Molmil
Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase
分子名称: Acetyl-CoA acetyltransferase, POTASSIUM ION, SULFATE ION
著者Anderson, S.M, Wawrzak, Z, Onopriyenko, O, Peterson, S.N, Anderson, W.F, Savchenko, A, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-07-07
公開日2011-07-20
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of the Bacillus anthracis acetyl-CoA acetyltransferase
TO BE PUBLISHED
7CW5
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Acetyl-CoA acetyltransferase from Bacillus cereus ATCC 14579
分子名称: Acetyl-CoA acetyltransferase, COENZYME A
著者Hong, J, Kim, K.J.
登録日2020-08-27
公開日2020-10-07
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of an acetyl-CoA acetyltransferase from PHB producing bacterium Bacillus cereus ATCC 14579.
Biochem.Biophys.Res.Commun., 533, 2020
2WUA
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Structure of the peroxisomal 3-ketoacyl-CoA thiolase from Sunflower
分子名称: ACETOACETYL COA THIOLASE
著者Pye, V.E, Christensen, C.E, Dyer, J.H, Arent, S, Henriksen, A.
登録日2009-10-01
公開日2010-05-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Peroxisomal Plant 3-Ketoacyl-Coa Thiolases Structure and Activity are Regulated by a Sensitive Redox Switch
J.Biol.Chem., 285, 2010
2WU9
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Crystal structure of peroxisomal KAT2 from Arabidopsis thaliana
分子名称: 1,2-ETHANEDIOL, 3-KETOACYL-COA THIOLASE 2, PEROXISOMAL
著者Pye, V.E, Christensen, C.E, Dyer, J.H, Arent, S, Henriksen, A.
登録日2009-10-01
公開日2010-05-12
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Peroxisomal Plant 3-Ketoacyl-Coa Thiolases Structure and Activity are Regulated by a Sensitive Redox Switch
J.Biol.Chem., 285, 2010
6L2G
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Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase
分子名称: Acetyl-CoA-acetyltransferase, putative
著者Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W.
登録日2019-10-03
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
6L2C
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Crystal structure of Aspergillus fumigatus mitochondrial acetyl-CoA acetyltransferase in complex with CoA
分子名称: Acetyl-CoA-acetyltransferase, putative, COENZYME A
著者Zhang, Y, Wei, W, Raimi, O.G, Ferenbach, A.T, Fang, W.
登録日2019-10-03
公開日2020-02-12
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.44 Å)
主引用文献Aspergillus fumigatus Mitochondrial Acetyl Coenzyme A Acetyltransferase as an Antifungal Target.
Appl.Environ.Microbiol., 86, 2020
3SVK
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BU of 3svk by Molmil
Crystal structure of Acetyl-CoA acetyltransferase from Mycobacterium avium
分子名称: Acetyl-CoA acetyltransferase, CHLORIDE ION
著者Seattle Structural Genomics Center for Infectious Disease (SSGCID)
登録日2011-07-12
公開日2011-08-03
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Increasing the structural coverage of tuberculosis drug targets.
Tuberculosis (Edinb), 95, 2015
7XLY
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Crystal structure of FadA2 (Rv0243) from the fatty acid metabolic pathway of Mycobacterium tuberculosis
分子名称: Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (Beta-ketothiolase), SULFATE ION
著者Singh, R, Kundu, P, Singh, B.K, Bhattacharyya, S, Das, A.K.
登録日2022-04-23
公開日2023-04-26
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Crystal structure of FadA2 thiolase from Mycobacterium tuberculosis and prediction of its substrate specificity and membrane-anchoring properties.
Febs J., 290, 2023
7VTR
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3-ketoacyl-CoA thiolase Tfu_0875
分子名称: Thiolase
著者Liu, L.X, Zhou, S.H, Deng, Y.
登録日2021-10-30
公開日2022-11-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Rational Design of the Substrate Tunnel of beta-Ketothiolase Reveals a Local Cationic Domain Modulated Rule that Improves the Efficiency of Claisen Condensation
Acs Catalysis, 13, 2023
4W61
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Crystal structure of beta-ketoacyl thiolase B (BktB) from Ralstonia eutropha
分子名称: Beta-ketothiolase BktB
著者Fage, C.D, Keatinge-Clay, A.T.
登録日2014-08-19
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Coenzyme A-free activity, crystal structure, and rational engineering of a promiscuous beta-ketoacyl thiolase fromRalstonia eutropha.
J. Mol. Catal., B Enzym., 121, 2015

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件を2024-08-07に公開中

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