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PDB: 195 件
7KC0
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BU of 7kc0 by Molmil
Structure of the Saccharomyces cerevisiae replicative polymerase delta in complex with a primer/template and the PCNA clamp
分子名称: 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA (25-MER), DNA (5'-D(P*AP*TP*GP*AP*CP*CP*AP*TP*GP*AP*TP*TP*AP*CP*GP*AP*AP*TP*TP*GP*C)-3'), ...
著者Zheng, F, Georgescu, R, Li, H, O'Donnell, M.E.
登録日2020-10-04
公開日2020-12-02
最終更新日2020-12-16
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Structure of eukaryotic DNA polymerase delta bound to the PCNA clamp while encircling DNA.
Proc.Natl.Acad.Sci.USA, 117, 2020
7KQ1
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BU of 7kq1 by Molmil
PCNA bound to truncated peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-PHE-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2020-11-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA.
J.Biol.Chem., 296, 2021
7KQ0
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BU of 7kq0 by Molmil
PCNA bound to peptide mimetic
分子名称: LYS-ARG-ARG-GLN-THR-SER-MET-THR-ASP-TYR-TYR-HIS-SER-LYS-ARG, Proliferating cell nuclear antigen
著者Vandborg, B.A, Bruning, J.B.
登録日2020-11-13
公開日2021-05-19
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Unlocking the PIP-box: A peptide library reveals interactions that drive high-affinity binding to human PCNA.
J.Biol.Chem., 296, 2021
5V7L
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BU of 5v7l by Molmil
PCNA mutant R61A/D63A Protein Defective in Gene Silencing
分子名称: Proliferating cell nuclear antigen
著者Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M.
登録日2017-03-20
公開日2018-03-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.201 Å)
主引用文献Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring.
PLoS ONE, 13, 2018
5IY4
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BU of 5iy4 by Molmil
Crystal structure of human PCNA in complex with the PIP box of DVC1
分子名称: DVC1 PIP box, Proliferating cell nuclear antigen
著者Jiang, T, Xu, M, Wang, Y.
登録日2016-03-24
公開日2016-06-08
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.945 Å)
主引用文献Crystal structure of human PCNA in complex with the PIP box of DVC1
Biochem.Biophys.Res.Commun., 474, 2016
1ISQ
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BU of 1isq by Molmil
Pyrococcus furiosus PCNA complexed with RFCL PIP-box peptide
分子名称: Proliferating Cell Nuclear Antigen, replication factor C large subunit
著者Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
登録日2001-12-19
公開日2002-10-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Physical interaction between proliferating cell nuclear antigen and replication factor C from Pyrococcus furiosus
Genes Cells, 7, 2002
1IZ5
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BU of 1iz5 by Molmil
Pyrococcus furiosus PCNA mutant (Met73Leu, Asp143Ala, Asp147Ala): orthorhombic form
分子名称: Proliferating cell nuclear antigen
著者Matsumiya, S, Ishino, S, Ishino, Y, Morikawa, K.
登録日2002-09-23
公開日2003-04-01
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Intermolecular ion pairs maintain the toroidal structure of Pyrococcus furiosus PCNA
PROTEIN SCI., 12, 2003
5MLW
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BU of 5mlw by Molmil
Crystal structure of human PCNA in complex with ZRANB3 APIM motif peptide
分子名称: APIM motif peptide, Proliferating cell nuclear antigen, SULFATE ION
著者Ariza, A.
登録日2016-12-07
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
5MLO
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BU of 5mlo by Molmil
Crystal structure of human PCNA in complex with ZRANB3 PIP box peptide
分子名称: Proliferating cell nuclear antigen, SODIUM ION, ZRANB3 PIP box peptide
著者Ariza, A.
登録日2016-12-07
公開日2017-06-28
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (1.96 Å)
主引用文献Structural insights into the function of ZRANB3 in replication stress response.
Nat Commun, 8, 2017
5MAV
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BU of 5mav by Molmil
Crystal structure of human PCNA in complex with PARG (poly(ADP-ribose) glycohydrolase) peptide.
分子名称: Poly (ADP-ribose) glycohydrolase, Proliferating cell nuclear antigen
著者Grishkovskaya, I, Djinovic-Carugo, K, Slade, D.
登録日2016-11-06
公開日2017-08-02
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.575 Å)
主引用文献A novel non-canonical PIP-box mediates PARG interaction with PCNA.
Nucleic Acids Res., 45, 2017
4YHR
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BU of 4yhr by Molmil
Crystal Structure of Yeast Proliferating Cell Nuclear Antigen
分子名称: Proliferating cell nuclear antigen
著者Litman, J.M, Nguyen, V.Q, Kondratick, C.M, Powers, K.T, Schnieders, M.J, Washington, M.T.
登録日2015-02-27
公開日2015-03-18
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (2.9502 Å)
主引用文献Dead-End Elimination with a Polarizable Force Field Repacks PCNA Models from Low-Resolution X-ray Diffraction into Atomic Resolution Structures
To be published
5MOM
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BU of 5mom by Molmil
Crystal Structure of PCNA encoding the hypomorphic mutation S228I
分子名称: Proliferating cell nuclear antigen
著者Biasutto, A.J, Mancini, E.J, Green, C.M, Wilson, R.H.C.
登録日2016-12-14
公開日2017-01-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献PCNA dependent cellular activities tolerate dramatic perturbations in PCNA client interactions.
DNA Repair (Amst.), 50, 2017
4ZTD
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BU of 4ztd by Molmil
Crystal Structure of Human PCNA in complex with a TRAIP peptide
分子名称: ALA-GLY-ALA-GLY-ALA, ALA-PHE-GLN-ALA-LYS-LEU-ASP-THR-PHE-LEU-TRP-SER, Proliferating cell nuclear antigen
著者Montoya, G, Mortuza, G.B, Blanco, F.J, Ibanez de Opakua, A.
登録日2015-05-14
公開日2015-12-16
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.199 Å)
主引用文献TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress.
J.Cell Biol., 212, 2016
5A6D
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BU of 5a6d by Molmil
Proliferating Cell Nuclear Antigen, PCNA, from Thermococcus gammatolerans
分子名称: DNA POLYMERASE SLIDING CLAMP
著者Venancio-Landeros, A, Cardona-Felix, C.S, Rudino-Pinera, E.
登録日2015-06-25
公開日2016-07-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Cloning, recombinant production and crystallographic structure of Proliferating Cell Nuclear Antigen from radioresistant archaeon Thermococcus gammatolerans.
Biochem Biophys Rep, 8, 2016
5AUJ
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BU of 5auj by Molmil
Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative
分子名称: DNA polymerase sliding clamp
著者Watanabe, Y, Oyama, T.
登録日2015-04-21
公開日2016-04-27
最終更新日2020-02-19
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Pyrococcus furiosus proliferating cell nuclear antigen (PCNA) SeMet derivative
To Be Published
3V62
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BU of 3v62 by Molmil
Structure of the S. cerevisiae Srs2 C-terminal domain in complex with PCNA conjugated to SUMO on lysine 164
分子名称: ATP-dependent DNA helicase SRS2, N-ETHYLMALEIMIDE, Proliferating cell nuclear antigen, ...
著者Armstrong, A.A, Mohideen, F, Lima, C.D.
登録日2011-12-18
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
Nature, 483, 2012
6EHT
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BU of 6eht by Molmil
Modulation of PCNA sliding surface by p15PAF suggests a suppressive mechanism for cisplatin-induced DNA lesion bypass by pol eta holoenzyme
分子名称: DNA (5'-D(P*AP*TP*AP*CP*GP*AP*TP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*AP*TP*CP*GP*TP*AP*T)-3'), PCNA-associated factor, ...
著者De March, M, Barrera-Vilarmau, S, Mentegari, E, Merino, N, Bressan, E, Maga, G, Crehuet, R, Onesti, S, Blanco, F.J, De Biasio, A.
登録日2017-09-15
公開日2018-08-08
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
3LX2
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BU of 3lx2 by Molmil
Crystal Structure analysis of PCNA from Thermococcus kodakaraensis tk0582
分子名称: DNA polymerase sliding clamp 2, SULFATE ION
著者Ladner, J.E, Kelman, Z, Pan, M.
登録日2010-02-24
公開日2011-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of two active proliferating cell nuclear antigens (PCNAs) encoded by Thermococcus kodakaraensis.
Proc.Natl.Acad.Sci.USA, 108, 2011
6FCM
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BU of 6fcm by Molmil
Crystal structure of human PCNA
分子名称: Proliferating cell nuclear antigen
著者Housset, D, Frachet, P.
登録日2017-12-20
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
7QNZ
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BU of 7qnz by Molmil
human Lig1-DNA-PCNA complex reconstituted in absence of ATP
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Oligo13P, ...
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2021-12-23
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (4.58 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
7QO1
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complex of DNA ligase I and FEN1 on PCNA and DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase 1, Flap endonuclease 1, ...
著者Blair, K, Tehseen, M, Raducanu, V.S, Shahid, T, Lancey, C, Cruehet, R, Hamdan, S, De Biasio, A.
登録日2021-12-23
公開日2023-01-11
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Mechanism of human Lig1 regulation by PCNA in Okazaki fragment sealing.
Nat Commun, 13, 2022
6FCN
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BU of 6fcn by Molmil
Crystal structure of human PCNA soaked with p47phox(106-127) peptide
分子名称: Proliferating cell nuclear antigen
著者Housset, D, Frachet, P.
登録日2017-12-20
公開日2019-01-30
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Cytosolic PCNA interacts with p47phox and controls NADPH oxidase NOX2 activation in neutrophils.
J.Exp.Med., 216, 2019
7RPX
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BU of 7rpx by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA
分子名称: DNA ligase, DNA polymerase sliding clamp 1, DNA polymerase sliding clamp 2, ...
著者Sverzhinsky, A, Pascal, J.M.
登録日2021-08-04
公開日2021-11-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
7RPO
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BU of 7rpo by Molmil
Archaeal DNA ligase and heterotrimeric PCNA in complex with non-ligatable DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ...
著者Sverzhinsky, A, Pascal, J.M.
登録日2021-08-03
公開日2021-11-17
最終更新日2022-03-16
実験手法ELECTRON MICROSCOPY (4.16 Å)
主引用文献Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022
7RPW
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Archaeal DNA ligase and heterotrimeric PCNA in complex with adenylated DNA
分子名称: ADENOSINE MONOPHOSPHATE, DNA ligase, DNA polymerase sliding clamp 1, ...
著者Sverzhinsky, A, Pascal, J.M.
登録日2021-08-04
公開日2021-11-17
最終更新日2024-06-05
実験手法ELECTRON MICROSCOPY (4.38 Å)
主引用文献Cryo-EM structures and biochemical insights into heterotrimeric PCNA regulation of DNA ligase.
Structure, 30, 2022

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