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PDB: 73 件

6HZY
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BU of 6hzy by Molmil
Crystal structure of a bacterial fucosidase with inhibitor FucPUG
分子名称: 1,2-ETHANEDIOL, Alpha-L-fucosidase, SULFATE ION, ...
著者Wu, L, Davies, G.J, Stubbs, K.A, Coyle, T, Debowski, A.W.
登録日2018-10-24
公開日2019-02-20
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Synthetic and Crystallographic Insight into Exploiting sp2Hybridization in the Development of alpha-l-Fucosidase Inhibitors.
Chembiochem, 20, 2019
1ODU
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BU of 1odu by Molmil
CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA ALPHA-FUCOSIDASE IN COMPLEX WITH FUCOSE
分子名称: PUTATIVE ALPHA-L-FUCOSIDASE, beta-L-fucopyranose
著者Sulzenbacher, G, Bignon, C, Bourne, Y, Henrissat, B.
登録日2003-03-14
公開日2004-01-15
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal Structure of Thermotoga Maritima {Alpha}-L-Fucosidase: Insights Into the Catalytic Mechanism and the Molecular Basis for Fucosidosis
J.Biol.Chem., 279, 2004
6GN6
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BU of 6gn6 by Molmil
Alpha-L-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus
分子名称: Alpha-L-fucosidase, DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, ...
著者Kovalova, T, Koval, T, Lipovova, P, Dohnalek, J.
登録日2018-05-30
公開日2018-12-26
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Active site complementation and hexameric arrangement in the GH family 29; a structure-function study of alpha-l-fucosidase isoenzyme 1 from Paenibacillus thiaminolyticus.
Glycobiology, 29, 2019
5HDR
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BU of 5hdr by Molmil
Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine
分子名称: Alpha-L-fucosidase, IMIDAZOLE, SULFATE ION, ...
著者Wright, D.W, Davies, G.J.
登録日2016-01-05
公開日2016-02-03
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine
To Be Published
4WSJ
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BU of 4wsj by Molmil
Crystal structure of a bacterial fucodiase in complex with 1-((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)ethan-1-one
分子名称: Alpha-L-fucosidase, N-[(1S,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methylcyclohexyl]acetamide, SULFATE ION
著者Davies, G.J, Wright, D.W.
登録日2014-10-28
公開日2014-11-05
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.64 Å)
主引用文献In vitroandin vivocomparative and competitive activity-based protein profiling of GH29 alpha-l-fucosidases.
Chem Sci, 6, 2015
4WSK
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BU of 4wsk by Molmil
Crystal structure of a bacterial fucosidase with phenyl((1R,2R,3R,4R,5R,6R)-2,3,4-trihydroxy-5-methyl-7-azabicyclo[4.1.0]heptan-7-yl)methanone
分子名称: Alpha-L-fucosidase, IMIDAZOLE, N-[(1S,2R,3R,4S,5R)-3,4,5-trihydroxy-2-methylcyclohexyl]benzamide, ...
著者Davies, G.J.
登録日2014-10-28
公開日2014-11-12
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.92 Å)
主引用文献In vitroandin vivocomparative and competitive activity-based protein profiling of GH29 alpha-l-fucosidases.
Chem Sci, 6, 2015
5I5R
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BU of 5i5r by Molmil
Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine
分子名称: (2S,3S,4R,5S,2'S,3'S,4'R,5'S)-2,2'-(butane-1,4-diyl)bis(5-methylpyrrolidine-3,4-diol), Alpha-L-fucosidase, IMIDAZOLE, ...
著者Wright, D.W, Davies, G.J.
登録日2016-02-15
公開日2016-03-02
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Will be disclosed later
To Be Published
8P1S
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BU of 8p1s by Molmil
Bifidobacterium asteroides alpha-L-fucosidase (TT1819) in complex with fucose.
分子名称: 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Bifidobacterium asteroides alpha-L-fucosidase (TT1819), ...
著者Owen, C.D, Penner, M, Gascuena, A.N, Wu, H, Hernando, P.J, Monaco, S, Le Gall, G, Gardner, R, Ndeh, D, Urbanowicz, P.A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N.
登録日2023-05-12
公開日2024-05-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Exploring sequence, structure and function of microbial fucosidases from glycoside hydrolase GH29 family
To Be Published
8P1R
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BU of 8p1r by Molmil
Bifidobacterium asteroides alpha-L-fucosidase (TT1819) catalytic mutant.
分子名称: 1,2-ETHANEDIOL, Bifidobacterium asteroides alpha-L-fucosidase (TT1819) catalytic mutant, MAGNESIUM ION
著者Owen, C.D, Penner, M, Gascuena, A.N, Wu, H, Hernando, P.J, Monaco, S, Le Gall, G, Gardner, R, Ndeh, D, Urbanowicz, P.A, Spencer, D.I.R, Walsh, M.A, Angulo, J, Juge, N.
登録日2023-05-12
公開日2024-03-27
実験手法X-RAY DIFFRACTION (1.659 Å)
主引用文献Exploring sequence, structure and function of microbial fucosidases from glycoside hydrolase GH29 family
To Be Published
1HL8
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BU of 1hl8 by Molmil
CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA ALPHA-FUCOSIDASE
分子名称: PUTATIVE ALPHA-L-FUCOSIDASE
著者Sulzenbacher, G, Bignon, C, Bourne, Y, Henrissat, B.
登録日2003-03-14
公開日2004-01-15
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal Structure of Thermotoga Maritima Alpha-L-Fucosidase. Insights Into the Catalytic Mechanism and the Molecular Basis for Fucosidosis.
J.Biol.Chem., 279, 2004
1HL9
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BU of 1hl9 by Molmil
CRYSTAL STRUCTURE OF THERMOTOGA MARITIMA ALPHA-FUCOSIDASE IN COMPLEX WITH A MECHANISM BASED INHIBITOR
分子名称: 2-deoxy-2-fluoro-beta-L-fucopyranose, PUTATIVE ALPHA-L-FUCOSIDASE
著者Sulzenbacher, G, Bignon, C, Bourne, Y, Henrissat, B.
登録日2003-03-14
公開日2004-02-05
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Crystal Structure of Thermotoga Maritima {Alpha}-L-Fucosidase: Insights Into the Catalytic Mechanism and the Molecular Basis for Fucosidosis
J.Biol.Chem., 279, 2004
4PCT
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BU of 4pct by Molmil
Crystal structure of a bacterial fucosidase with iminocyclitol (2S,3S,4R,5S)-3,4-dihydroxy-2-ethynyl-5-methylpyrrolidine
分子名称: (2S,3S,4R,5S)-2-ethynyl-5-methylpyrrolidine-3,4-diol, Alpha-L-fucosidase, IMIDAZOLE, ...
著者Wright, D.W, Davies, G.J.
登録日2014-04-16
公開日2014-07-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Exploiting the Hydrophobic Terrain in Fucosidases with Aryl-Substituted Pyrrolidine Iminosugars.
Chembiochem, 16, 2015
7XSG
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BU of 7xsg by Molmil
Crystal structure of ClAgl29B
分子名称: Alpha-L-fucosidase, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Shishiuchi, R, Kang, H, Tagami, T, Okuyama, M.
登録日2022-05-14
公開日2023-01-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.609 Å)
主引用文献Discovery of alpha-l-Glucosidase Raises the Possibility of alpha-l-Glucosides in Nature.
Acs Omega, 7, 2022
7XSF
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BU of 7xsf by Molmil
Crystal structure of ClAgl29A
分子名称: Alpha-L-fucosidase, DI(HYDROXYETHYL)ETHER, GLYCEROL, ...
著者Shishiuchi, R, Kang, H, Tagami, T, Okuyama, M.
登録日2022-05-14
公開日2023-01-18
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.006 Å)
主引用文献Discovery of alpha-l-Glucosidase Raises the Possibility of alpha-l-Glucosides in Nature.
Acs Omega, 7, 2022
7XSH
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BU of 7xsh by Molmil
Crystal structure of ClAgl29B bound with L-glucose
分子名称: Alpha-L-fucosidase, CITRIC ACID, DI(HYDROXYETHYL)ETHER, ...
著者Shishiuchi, R, Kang, H, Tagami, T, Okuyama, M.
登録日2022-05-14
公開日2023-01-18
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.708 Å)
主引用文献Discovery of alpha-l-Glucosidase Raises the Possibility of alpha-l-Glucosides in Nature.
Acs Omega, 7, 2022
4PCS
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BU of 4pcs by Molmil
Crystal structure of a bacterial fucosidase with iminosugar (2S,3S,4R,5S)-3,4-dihydroxy-2-[2'-phenyl]ethynyl-5-methylpyrrolidine
分子名称: (2S,3R,4S,5S)-2-methyl-5-(phenylethynyl)pyrrolidine-3,4-diol, Alpha-L-fucosidase, IMIDAZOLE, ...
著者Davies, G.J, Wright, D.W, Behr, J.B.
登録日2014-04-16
公開日2014-07-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献Exploiting the Hydrophobic Terrain in Fucosidases with Aryl-Substituted Pyrrolidine Iminosugars.
Chembiochem, 16, 2015
4PEE
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BU of 4pee by Molmil
Crystal structure of a bacterial fucosidase with inhibitor 1-phenyl-4-[(2S,3S,4R,5S)-3,4-dihydroxy-5-methylpyrrolidin-2-yl]triazole
分子名称: (2S,3R,4S,5S)-2-methyl-5-(1-phenyl-1H-1,2,3-triazol-4-yl)pyrrolidine-3,4-diol, Alpha-L-fucosidase, IMIDAZOLE, ...
著者Wright, D.W, Davies, G.J, Behr, J.B.
登録日2014-04-23
公開日2014-07-09
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Exploiting the Hydrophobic Terrain in Fucosidases with Aryl-Substituted Pyrrolidine Iminosugars.
Chembiochem, 16, 2015
2WVV
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BU of 2wvv by Molmil
Crystal structure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron
分子名称: 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-L-FUCOSIDASE, GLYCEROL, ...
著者Lammerts van Bueren, A, Ardevol, A, Fayers-Kerr, J, Luo, B, Zhang, Y, Sollogoub, M, Bleriot, Y, Rovira, C, Davies, G.J.
登録日2009-10-20
公開日2010-02-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.73 Å)
主引用文献Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach
J.Am.Chem.Soc., 132, 2010
2WVS
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BU of 2wvs by Molmil
Crystal structure of an alpha-L-fucosidase GH29 trapped covalent intermediate from Bacteroides thetaiotaomicron in complex with 2- fluoro-fucosyl fluoride using an E288Q mutant
分子名称: 2-deoxy-2-fluoro-beta-L-fucopyranose, ALPHA-L-FUCOSIDASE, SULFATE ION
著者Lammerts van Bueren, A, Ardevol, A, Fayers-Kerr, J, Luo, B, Zhang, Y, Sollogoub, M, Bleriot, Y, Rovira, C, Davies, G.J.
登録日2009-10-20
公開日2010-02-02
最終更新日2020-07-29
実験手法X-RAY DIFFRACTION (2.19 Å)
主引用文献Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach
J.Am.Chem.Soc., 132, 2010
2WSP
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BU of 2wsp by Molmil
Thermotoga maritima alpha-L-fucosynthase, TmD224G, in complex with alpha-L-Fuc-(1-2)-beta-L-Fuc-N3
分子名称: ALPHA-L-FUCOSIDASE, PUTATIVE, alpha-L-fucopyranose-(1-2)-beta-L-fucosyl-azide
著者Sulzenbacher, G, Lipski, A, Cobucci-Ponzano, B, Conte, F, Bedini, E, Corsaro, M.M, Parrilli, M, Dal Piaz, F, Lepore, L, Rossi, M, Moracci, M.
登録日2009-09-08
公開日2010-01-19
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Beta-Glycosyl Azides as Substrates for Alpha-Glycosynthases: Preparation of Novel Efficient Alpha-L-Fucosynthases
Chem.Biol., 16, 2009
2WVU
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BU of 2wvu by Molmil
Crystal structure of a Michaelis complex of alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron with the synthetic substrate 4- nitrophenyl-alpha-L-fucose
分子名称: 4-nitrophenyl 6-deoxy-alpha-L-galactopyranoside, ALPHA-L-FUCOSIDASE, SULFATE ION
著者Lammerts van Bueren, A, Ardevol, A, Fayers-Kerr, J, Luo, B, Zhang, Y, Sollogoub, M, Bleriot, Y, Rovira, C, Davies, G.J.
登録日2009-10-20
公開日2010-02-02
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach
J.Am.Chem.Soc., 132, 2010
2XII
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BU of 2xii by Molmil
CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH AN EXTENDED 9-FLUORENONE IMINOSUGAR INHIBITOR
分子名称: 9-oxo-N-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyl-piperidin-2-yl]methyl]fluorene-1-carboxamide, ALPHA-L-FUCOSIDASE, GLYCEROL, ...
著者Lammerts van Bueren, A, Popat, S.D, Lin, C.H, Davies, G.J.
登録日2010-06-30
公開日2010-07-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural and Thermodynamic Analyses of Alpha-L-Fucosidase Inhibitors.
Chembiochem, 11, 2010
2WVT
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BU of 2wvt by Molmil
Crystal structure of an alpha-L-fucosidase GH29 from Bacteroides thetaiotaomicron in complex with a novel iminosugar fucosidase inhibitor
分子名称: (2S,3R,5R,6S)-3,4,5-TRIHYDROXY-2,6-BIS(HYDROXYMETHYL)PIPERIDINIUM, ALPHA-L-FUCOSIDASE, GLYCEROL, ...
著者Lammerts van Bueren, A, Ardevol, A, Fayers-Kerr, J, Luo, B, Zhang, Y, Sollogoub, M, Bleriot, Y, Rovira, C, Davies, G.J.
登録日2009-10-20
公開日2010-02-02
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Analysis of the Reaction Coordinate of Alpha-L-Fucosidases: A Combined Structural and Quantum Mechanical Approach.
J.Am.Chem.Soc., 132, 2010
2XIB
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BU of 2xib by Molmil
CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH DEOXYFUCONOJIRIMYCIN
分子名称: (2S,3R,4S,5R)-2-METHYLPIPERIDINE-3,4,5-TRIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ALPHA-L-FUCOSIDASE, ...
著者Lammerts van Bueren, A, Popat, S.D, Lin, C.H, Davies, G.J.
登録日2010-06-28
公開日2010-07-21
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structural and Thermodynamic Analyses of Alpha-L-Fucosidase Inhibitors.
Chembiochem, 11, 2010
6O1C
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BU of 6o1c by Molmil
Alpha-L-fucosidase AlfC D200A mutant in complex with 4-nitrophenyl-a-L-fucopyranoside substrate
分子名称: 4-nitrophenyl 6-deoxy-alpha-L-galactopyranoside, AlfC
著者Klontz, E.H, Sundberg, E.J.
登録日2019-02-19
公開日2020-02-19
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure and dynamics of an alpha-fucosidase reveal a mechanism for highly efficient IgG transfucosylation.
Nat Commun, 11, 2020

 

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