Loading
PDBj
English日本語简体中文繁體中文한국어
✖
ﾒﾆｭｰPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 595 件
7AUH
DownloadVisualize
BU of 7auh by Molmil
Structure of P. aeruginosa PBP3 in complex with vaborbactam
分子名称: GLYCEROL, Peptidoglycan D,D-transpeptidase FtsI, Vaborbactam
著者Newman, H, Bellini, B, Dowson, C.G.
登録日2020-11-03
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.012 Å)
主引用文献High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes.
J.Med.Chem., 64, 2021
7AU1
DownloadVisualize
BU of 7au1 by Molmil
Structure of P. aeruginosa PBP3 in complex with a benzoxaborole (Compound 12)
分子名称: 2-(6-(((R)-2-amino-2-oxo-1-phenylethyl)carbamoyl)-1-hydroxy-1,3-dihydrobenzo[c][1,2]oxaborol-3-yl)acetic acid, DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, ...
著者Newman, H, Bellini, B, Dowson, C.G.
登録日2020-11-02
公開日2021-08-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.36 Å)
主引用文献High-Throughput Crystallography Reveals Boron-Containing Inhibitors of a Penicillin-Binding Protein with Di- and Tricovalent Binding Modes.
J.Med.Chem., 64, 2021
6R40
DownloadVisualize
BU of 6r40 by Molmil
Apo structure of R504C mutant of Pseudomonas aeruginosa Penicillin-Binding Protein 3 (PBP3)
分子名称: Peptidoglycan D,D-transpeptidase FtsI
著者Bellini, D, Dowson, C.G.
登録日2019-03-21
公開日2020-02-19
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Novel and Improved Crystal Structures of H. influenzae, E. coli and P. aeruginosa Penicillin-Binding Protein 3 (PBP3) and N. gonorrhoeae PBP2: Toward a Better Understanding of beta-Lactam Target-Mediated Resistance.
J.Mol.Biol., 431, 2019
8EXP
DownloadVisualize
BU of 8exp by Molmil
Cryo-EM structure of S. aureus BlaR1 with C2 symmetry
分子名称: Beta-lactam sensor/signal transducer BlaR1, ZINC ION
著者Worrall, L.J, Alexander, J.A.N, Vuckovic, M, Strynadka, N.C.J.
登録日2022-10-25
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus.
Nature, 613, 2023
8EXS
DownloadVisualize
BU of 8exs by Molmil
Cryo-EM structure of S. aureus BlaR1 F284A mutant
分子名称: Beta-lactam sensor/signal transducer BlaR1, ZINC ION
著者Alexander, J.A.N, Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2022-10-25
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.3 Å)
主引用文献Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus.
Nature, 613, 2023
8EXR
DownloadVisualize
BU of 8exr by Molmil
Cryo-EM structure of S. aureus BlaR1 TM and zinc metalloprotease domain
分子名称: (2S)-3-{[{[(2S)-2,3-DIHYDROXYPROPYL]OXY}(HYDROXY)PHOSPHORYL]OXY}-2-[(6E)-HEXADEC-6-ENOYLOXY]PROPYL (8E)-OCTADEC-8-ENOATE, Beta-lactam sensor/signal transducer BlaR1, PHOSPHATE ION, ...
著者Worrall, L.J, Alexander, J.A.N, Vuckovic, M, Strynadka, N.C.J.
登録日2022-10-25
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus.
Nature, 613, 2023
8EXT
DownloadVisualize
BU of 8ext by Molmil
Cryo-EM structure of S. aureus BlaR1 F284A mutant in complex with ampicillin
分子名称: Beta-lactam sensor/signal transducer BlaR1, ZINC ION
著者Alexander, J.A.N, Hu, J, Worrall, L.J, Strynadka, N.C.J.
登録日2022-10-25
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus.
Nature, 613, 2023
8EXQ
DownloadVisualize
BU of 8exq by Molmil
Cryo-EM structure of S. aureus BlaR1 with C1 symmetry
分子名称: Beta-lactam sensor/signal transducer BlaR1, ZINC ION
著者Worrall, L.J, Alexander, J.A.N, Vuckovic, M, Strynadka, N.C.J.
登録日2022-10-25
公開日2023-01-11
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Structural basis of broad-spectrum beta-lactam resistance in Staphylococcus aureus.
Nature, 613, 2023
8F3H
DownloadVisualize
BU of 8f3h by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) S466 insertion variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3L
DownloadVisualize
BU of 8f3l by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant penicillin bound form from Enterococcus faecium
分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3O
DownloadVisualize
BU of 8f3o by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Peti, W, Page, R.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3S
DownloadVisualize
BU of 8f3s by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant penicillin bound form from Enterococcus faecium
分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F67
DownloadVisualize
BU of 8f67 by Molmil
Crystal structure of the refolded Penicillin Binding Protein 5 (PBP5) of Enterococcus faecium
分子名称: Pbp5, SULFATE ION
著者D'Andrea, E.D, Schoenle, M.V, Choy, M.S, Peti, W, Page, R.
登録日2022-11-16
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3T
DownloadVisualize
BU of 8f3t by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SODIUM ION, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.56 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3I
DownloadVisualize
BU of 8f3i by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) S466 insertion variant penicillin bound form from Enterococcus faecium
分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3Z
DownloadVisualize
BU of 8f3z by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) S422A variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者Schoenle, M.V, D'Andrea, E.D, Choy, M.S, Peti, W, Page, R.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3U
DownloadVisualize
BU of 8f3u by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I V629E variant penicillin bound form from Enterococcus faecium
分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3N
DownloadVisualize
BU of 8f3n by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion penicillin bound form from Enterococcus faecium
分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (2.99 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3F
DownloadVisualize
BU of 8f3f by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Hunashal, Y, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3R
DownloadVisualize
BU of 8f3r by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M T499I variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3P
DownloadVisualize
BU of 8f3p by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) R464A variant penicillin bound form from Enterococcus faecium
分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2024-03-13
実験手法X-RAY DIFFRACTION (3.09 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3J
DownloadVisualize
BU of 8f3j by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3M
DownloadVisualize
BU of 8f3m by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485A variant with S466 insertion apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.81 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3G
DownloadVisualize
BU of 8f3g by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) T485M variant in the penicillin bound form from Enterococcus faecium
分子名称: OPEN FORM - PENICILLIN G, Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Choy, M.S, Schoenle, M.V, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2024-10-09
実験手法X-RAY DIFFRACTION (3.59 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023
8F3Q
DownloadVisualize
BU of 8f3q by Molmil
Crystal structure of Penicillin Binding Protein 5 (PBP5) Y460A variant apo form from Enterococcus faecium
分子名称: Penicillin binding protein 5, SULFATE ION
著者D'Andrea, E.D, Schoenle, M.V, Choy, M.S, Page, R, Peti, W.
登録日2022-11-10
公開日2023-07-05
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Molecular Basis for Resistance of E. faecium PBP5 to beta-lactam Antibiotics
Nat Commun, 2023

225946

件を2024-10-09に公開中

PDB statisticsPDBj update infoContact PDBjnumon