4MK4
 
 | | S197C variant of human ferrochelatase. | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A. | | 登録日 | 2013-09-04 | | 公開日 | 2013-09-25 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | S197C variant of human ferrochelatase.
To be Published
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3M4Z
 | | Crystal Structure of B. subtilis ferrochelatase with Cobalt bound at the active site | | 分子名称: | CHLORIDE ION, COBALT (II) ION, Ferrochelatase, ... | | 著者 | Soderberg, C.A.G, Hansson, M.D, Sreekanth, R, Al-Karadaghi, S, Hansson, M. | | 登録日 | 2010-03-12 | | 公開日 | 2010-11-10 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (1.94 Å) | | 主引用文献 | Bacterial ferrochelatase goes human: Tyr13 determines the apparent metal specificity of Bacillus subtilis ferrochelatase
To be Published
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3W1W
 | | Protein-drug complex | | 分子名称: | 1,2-ETHANEDIOL, 2-HYDROXYBENZOIC ACID, CHOLIC ACID, ... | | 著者 | Ishii, R, Gupta, V, Yamaguchi, Y, Handa, H, Nureki, O. | | 登録日 | 2012-11-21 | | 公開日 | 2013-10-09 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.006 Å) | | 主引用文献 | Salicylic Acid induces mitochondrial injury by inhibiting ferrochelatase heme biosynthesis activity
Mol.Pharmacol., 84, 2013
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7L78
 | | H235C variant of Yeast Ferrochelatase | | 分子名称: | CHOLIC ACID, Ferrochelatase, mitochondrial | | 著者 | Lanzilotta, W.N, Medlock, A.E. | | 登録日 | 2020-12-27 | | 公開日 | 2021-11-24 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mitochondrial contact site and cristae organizing system (MICOS) machinery supports heme biosynthesis by enabling optimal performance of ferrochelatase.
Redox Biol, 46, 2021
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2C8J
 | | CRYSTAL STRUCTURE OF ferrochelatase HemH-1 from Bacillus anthracis, str. Ames | | 分子名称: | FERROCHELATASE 1 | | 著者 | Muller, A, Lebedev, A.A, Moroz, O.V, Blagova, E.V, Levdikov, V.M, Fogg, M.J, Brannigan, J.A, Wilkinson, A.J, Wilson, K.S. | | 登録日 | 2005-12-05 | | 公開日 | 2007-05-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Crystal Structure of Ferrochelatase Hemh-1 from Bacillus Anthracis, Str. Ames
To be Published
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3AQI
 | | H240A variant of human ferrochelatase | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.A, Dailey, H.A. | | 登録日 | 2010-11-03 | | 公開日 | 2012-01-25 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | H240A variant of human ferrochelatase
To be published
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1N0I
 | | Crystal Structure of Ferrochelatase with Cadmium bound at active site | | 分子名称: | CADMIUM ION, CHLORIDE ION, Ferrochelatase, ... | | 著者 | Lecerof, D, Fodje, M.N, Leon, R.A, Olsson, U, Hansson, A, Sigfridsson, E, Ryde, U, Hansson, M, Al-Karadaghi, S. | | 登録日 | 2002-10-14 | | 公開日 | 2003-05-27 | | 最終更新日 | 2024-02-14 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites
J.Biol.Inorg.Chem., 8, 2003
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4F4D
 | | F337R variant of human ferrochelatase | | 分子名称: | CHLORIDE ION, CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, ... | | 著者 | Lanzilotta, W.N, Medlock, A.E, Dailey, T.E, Dailey, H.A. | | 登録日 | 2012-05-10 | | 公開日 | 2012-09-12 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | F337R Variant of Human Ferrochelatase
TO BE PUBLISHED
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1HRK
 | | CRYSTAL STRUCTURE OF HUMAN FERROCHELATASE | | 分子名称: | CHOLIC ACID, FE2/S2 (INORGANIC) CLUSTER, FERROCHELATASE | | 著者 | Wu, C.K, Dailey, H.A, Rose, J.P, Burden, A, Sellers, V.M, Wang, B.-C. | | 登録日 | 2000-12-21 | | 公開日 | 2001-06-22 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The 2.0 A structure of human ferrochelatase, the terminal enzyme of heme biosynthesis.
Nat.Struct.Biol., 8, 2001
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9F0G
 | | LmCpfC H182A variant in complex with iron coproporhyrin III | | 分子名称: | 1,2-ETHANEDIOL, 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, CALCIUM ION, ... | | 著者 | Gabler, T, Hofbauer, S. | | 登録日 | 2024-04-16 | | 公開日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | LmCpfC H182A variant in complex with iron coproporhyrin III
To Be Published
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9F0F
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6SV3
 | | Structure of coproheme-LmCpfC | | 分子名称: | 1,3,5,8-TETRAMETHYL-PORPHINE-2,4,6,7-TETRAPROPIONIC ACID FERROUS COMPLEX, Ferrochelatase, GLYCEROL | | 著者 | Hofbauer, S, Helm, J, Djinovic-Carugo, K, Furtmueller, P.G. | | 登録日 | 2019-09-17 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.64000869 Å) | | 主引用文献 | Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase.
Febs J., 287, 2020
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8OFL
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8OMM
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6RWV
 | | Structure of apo-LmCpfC | | 分子名称: | Ferrochelatase, GLYCEROL, PHOSPHATE ION, ... | | 著者 | Hofbauer, S, Helm, J, Djinovic-Carugo, K, Furtmueller, P.G. | | 登録日 | 2019-06-06 | | 公開日 | 2019-12-18 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (1.6386379 Å) | | 主引用文献 | Crystal structures and calorimetry reveal catalytically relevant binding mode of coproporphyrin and coproheme in coproporphyrin ferrochelatase.
Febs J., 287, 2020
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7CTC
 | | FECH - inhibitor complex 1 | | 分子名称: | 2-(4-tert-butylphenyl)-5-[(quinolin-2-ylamino)methyl]-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Lee, S.J, Park, J. | | 登録日 | 2020-08-18 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | FECH - inhibitor complex 1
to be published
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7CT7
 | | FECH - inhibitor complex 2 | | 分子名称: | 2-[[(4-chlorophenyl)amino]methyl]-5-propyl-6H-[1,2,4]triazolo[1,5-a]pyrimidin-7-one, FE2/S2 (INORGANIC) CLUSTER, Ferrochelatase, ... | | 著者 | Lee, S.J, Park, J. | | 登録日 | 2020-08-18 | | 公開日 | 2021-08-18 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | FECH - inhibitor complex 1
to be published
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2AC2
 | | Crystal structure of the Tyr13Phe mutant variant of Bacillus subtilis Ferrochelatase with Zn(2+) bound at the active site | | 分子名称: | Ferrochelatase, ZINC ION | | 著者 | Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S. | | 登録日 | 2005-07-18 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism.
J.Mol.Biol., 352, 2005
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2AC4
 | | Crystal structure of the His183Cys mutant variant of Bacillus subtilis Ferrochelatase | | 分子名称: | Ferrochelatase | | 著者 | Shipovskov, S, Karlberg, T, Fodje, M, Hansson, M.D, Ferreira, G.C, Hansson, M, Reimann, C.T, Al-Karadaghi, S. | | 登録日 | 2005-07-18 | | 公開日 | 2005-09-20 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Metallation of the Transition-state Inhibitor N-methyl Mesoporphyrin by Ferrochelatase: Implications for the Catalytic Reaction Mechanism.
J.Mol.Biol., 352, 2005
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8AW7
 | | Structure of coproporphyrin III-LmCpfC R45L | | 分子名称: | Coproporphyrin III ferrochelatase, GLYCEROL, coproporphyrin III | | 著者 | Gabler, T, Hofbauer, S, Pfanzagl, V. | | 登録日 | 2022-08-29 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.64 Å) | | 主引用文献 | Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation.
Protein Sci., 32, 2023
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8AT8
 | | Structure of coproporphyrin III-LmCpfC | | 分子名称: | 1,2-ETHANEDIOL, ACETATE ION, CALCIUM ION, ... | | 著者 | Gabler, T, Hofbauer, S. | | 登録日 | 2022-08-22 | | 公開日 | 2022-12-28 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.51 Å) | | 主引用文献 | Active site architecture of coproporphyrin ferrochelatase with its physiological substrate coproporphyrin III: Propionate interactions and porphyrin core deformation.
Protein Sci., 32, 2023
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8BBV
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1LBQ
 | | The crystal structure of Saccharomyces cerevisiae ferrochelatase | | 分子名称: | Ferrochelatase | | 著者 | Karlberg, T, Lecerof, D, Gora, M, Silvegren, G, Labbe-Bois, R, Hansson, M, Al-Karadaghi, S. | | 登録日 | 2002-04-04 | | 公開日 | 2002-11-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Metal binding to Saccharomyces cerevisiae ferrochelatase
Biochemistry, 41, 2002
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1L8X
 | | Crystal Structure of Ferrochelatase from the Yeast, Saccharomyces cerevisiae, with Cobalt(II) as the Substrate Ion | | 分子名称: | COBALT (II) ION, Ferrochelatase | | 著者 | Karlberg, T, Lecerof, D, Gora, M, Silvegren, G, Labbe-Bois, R, Hansson, M, Al-Karadaghi, S. | | 登録日 | 2002-03-22 | | 公開日 | 2002-11-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Metal Binding to Saccharomyces cerevisiae Ferrochelatase
Biochemistry, 41, 2002
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1LD3
 | | Crystal Structure of B. subilis ferrochelatase with Zn(2+) bound at the active site. | | 分子名称: | Ferrochelatase, ZINC ION | | 著者 | Lecerof, D, Fodje, M.N, Leon, R.A, Olsson, U, Hansson, A, Sigfridsson, E, Ryde, U, Hansson, M, Al-Karadaghi, S. | | 登録日 | 2002-04-08 | | 公開日 | 2003-05-20 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Metal binding to Bacillus subtilis ferrochelatase and interaction between metal sites
J.Biol.Inorg.Chem., 8, 2003
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