8IWW
 
 | | hSPCA1 in the CaE1P-ADP state | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.71 Å) | | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWS
 | | hSPCA1 in the CaE2P state | | 分子名称: | BERYLLIUM TRIFLUORIDE ION, CALCIUM ION, Calcium-transporting ATPase type 2C member 1, ... | | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.42 Å) | | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWR
 | | hSPCA1 in the CaE1-ATP state | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1, MAGNESIUM ION, ... | | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | | 登録日 | 2023-03-31 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.52 Å) | | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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8IWP
 | | hSPCA1 in the CaE1 state | | 分子名称: | CALCIUM ION, Calcium-transporting ATPase type 2C member 1 | | 著者 | Liu, Z.M, Wu, M.Q, Wu, C. | | 登録日 | 2023-03-30 | | 公開日 | 2023-12-27 | | 実験手法 | ELECTRON MICROSCOPY (3.59 Å) | | 主引用文献 | Structure and transport mechanism of the human calcium pump SPCA1.
Cell Res., 33, 2023
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7EFL
 | | Crystal structure of the gastric proton pump K791S in (BYK)E2BeF state | | 分子名称: | (7R,8R,9S)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridine-7,8-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | | 著者 | Abe, K, Yamamoto, K, Irie, K. | | 登録日 | 2021-03-22 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | | 主引用文献 | Gastric proton pump with two occluded K + engineered with sodium pump-mimetic mutations.
Nat Commun, 12, 2021
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7EFM
 | | Crystal structure of the gastric proton pump K791S/E820D/Y340N in (BYK)E2BeF state | | 分子名称: | (7R,8R,9S)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridine-7,8-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | | 著者 | Abe, K, Yamamoto, K, Irie, K. | | 登録日 | 2021-03-22 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Gastric proton pump with two occluded K + engineered with sodium pump-mimetic mutations.
Nat Commun, 12, 2021
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7EFN
 | | Crystal structure of the gastric proton pump K791S/E820D/Y340N/E936V in (BYK)E2BeF state | | 分子名称: | (7R,8R,9S)-2,3-dimethyl-9-phenyl-7,8,9,10-tetrahydroimidazo[1,2-h][1,7]naphthyridine-7,8-diol, 2-acetamido-2-deoxy-beta-D-glucopyranose, MAGNESIUM ION, ... | | 著者 | Abe, K, Yamamoto, K, Irie, K. | | 登録日 | 2021-03-22 | | 公開日 | 2021-09-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Gastric proton pump with two occluded K + engineered with sodium pump-mimetic mutations.
Nat Commun, 12, 2021
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7E7S
 | | WT transporter state1 | | 分子名称: | CALCIUM ION, Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 | | 著者 | Zhang, Y, Watanabe, S, Tsutsumi, A, Inaba, K. | | 登録日 | 2021-02-27 | | 公開日 | 2021-09-08 | | 最終更新日 | 2022-02-23 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Cryo-EM analysis provides new mechanistic insight into ATP binding to Ca 2+ -ATPase SERCA2b.
Embo J., 40, 2021
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7D94
 | | Crystal Structure of the Na+,K+-ATPase in the E2P state with bound one Mg2+ and one Rb+ in the presence of bufalin | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Ogawa, H, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-12 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7DDF
 | | Crystal structures of Na+,K+-ATPase in complex with beryllium fluoride | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-29 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (4.62 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7E20
 | | Cryo EM structure of a K+-bound Na+,K+-ATPase in the E2 state | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q. | | 登録日 | 2021-02-04 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.7 Å) | | 主引用文献 | Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Nat Commun, 13, 2022
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7E21
 | | Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state with ATP-gamma-S | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q. | | 登録日 | 2021-02-04 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | | 主引用文献 | Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Nat Commun, 13, 2022
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7E1Z
 | | Cryo EM structure of a Na+-bound Na+,K+-ATPase in the E1 state | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Guo, Y.Y, Zhang, Y.Y, Yan, R.H, Huang, B.D, Ye, F.F, Wu, L.S, Chi, X.M, Zhou, Q. | | 登録日 | 2021-02-04 | | 公開日 | 2022-06-15 | | 最終更新日 | 2022-07-20 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Cryo-EM structures of recombinant human sodium-potassium pump determined in three different states.
Nat Commun, 13, 2022
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7DDK
 | | Crystal structures of Na+,K+-ATPase in complex with rostafuroxin | | 分子名称: | (3S,5R,8R,9S,10S,13S,14S,17S)-17-(furan-3-yl)-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,15,16-dodecahydro-1H-cyclopenta[a]phenanthrene-3,14,17-triol, 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-29 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.5 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7ET1
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7D91
 | | Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ (P4(3)2(1)2 symmetry) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Ogawa, H, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-12 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7DDH
 | | Crystal structures of Na+,K+-ATPase in complex with digoxin | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-29 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.46 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7DDL
 | | Crystal structures of Na+,K+-ATPase in complex with bufalin | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-29 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7D92
 | | Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ and anthroylouabain (P4(3)2(1)2 symmetry) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Ogawa, H, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-12 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.9 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7D93
 | | Crystal Structure of the Na+,K+-ATPase in the E2P state with bound Mg2+ and anthroylouabain (P2(1)2(1)2(1) symmetry) | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Kanai, R, Cornelius, F, Ogawa, H, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-12 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.65 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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7DDI
 | | Crystal structures of Na+,K+-ATPase in complex with digitoxin | | 分子名称: | 1,2-DIOLEOYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ogawa, H, Cornelius, F, Kanai, R, Motoyama, K, Vilsen, B, Toyoshima, C. | | 登録日 | 2020-10-29 | | 公開日 | 2021-01-27 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.72 Å) | | 主引用文献 | Binding of cardiotonic steroids to Na + ,K + -ATPase in the E2P state.
Proc.Natl.Acad.Sci.USA, 118, 2021
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2YN9
 | | Cryo-EM structure of gastric H+,K+-ATPase with bound rubidium | | 分子名称: | POTASSIUM-TRANSPORTING ATPASE ALPHA CHAIN 1, POTASSIUM-TRANSPORTING ATPASE SUBUNIT BETA | | 著者 | Abe, K, Tani, K, Friedrich, T, Fujiyoshi, Y. | | 登録日 | 2012-10-13 | | 公開日 | 2012-11-07 | | 最終更新日 | 2014-07-16 | | 実験手法 | ELECTRON CRYSTALLOGRAPHY (8 Å) | | 主引用文献 | Cryo-Em Structure of Gastric H+,K+-ATPase with a Single Occupied Cation-Binding Site.
Proc.Natl.Acad.Sci.USA, 109, 2012
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2YFY
 | | SERCA in the HnE2 State Complexed With Debutanoyl Thapsigargin | | 分子名称: | DEBUTANOYL THAPSIGARGIN, MAGNESIUM ION, POTASSIUM ION, ... | | 著者 | Sonntag, Y, Musgaard, M, Olesen, C, Schiott, B, Moller, J.V, Nissen, P, Thogersen, L. | | 登録日 | 2011-04-11 | | 公開日 | 2011-06-29 | | 最終更新日 | 2011-07-13 | | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | | 主引用文献 | Mutual Adaptation of a Membrane Protein and its Lipid Bilayer During Conformational Changes.
Nat.Commun., 2, 2011
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2ZBG
 | | Calcium pump crystal structure with bound AlF4 and TG in the absence of calcium | | 分子名称: | MAGNESIUM ION, OCTANOIC ACID [3S-[3ALPHA, 3ABETA, ... | | 著者 | Toyoshima, C, Ogawa, H, Norimatsu, Y. | | 登録日 | 2007-10-20 | | 公開日 | 2007-12-11 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | | 主引用文献 | How processing of aspartylphosphate is coupled to lumenal gating of the ion pathway in the calcium pump
Proc.Natl.Acad.Sci.Usa, 104, 2007
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2ZBD
 | | Crystal Structure of the SR Calcium Pump with Bound Aluminium Fluoride, ADP and Calcium | | 分子名称: | 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ADENOSINE-5'-DIPHOSPHATE, CALCIUM ION, ... | | 著者 | Toyoshima, C, Nomura, H, Tsuda, T, Ogawa, H, Norimatsu, Y. | | 登録日 | 2007-10-20 | | 公開日 | 2007-11-20 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Lumenal gating mechanism revealed in calcium pump crystal structures with phosphate analogues
Nature, 432, 2004
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