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PDB: 249 件

3OL9
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Poliovirus polymerase elongation complex with 3'-deoxy-CTP
分子名称: ISOPROPYL ALCOHOL, PYROPHOSPHATE 2-, Polymerase, ...
著者Gong, P, Peersen, O.B.
登録日2010-08-25
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
1SH0
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Crystal Structure of Norwalk Virus Polymerase (Triclinic)
分子名称: RNA Polymerase
著者Ng, K.K, Pendas-Franco, N, Rojo, J, Boga, J.A, Machin, A, Alonso, J.M, Parra, F.
登録日2004-02-24
公開日2004-03-09
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.17 Å)
主引用文献Crystal structure of norwalk virus polymerase reveals the carboxyl terminus in the active site cleft.
J.Biol.Chem., 279, 2004
4WYW
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Mutant K20E of 3D polymerase from Foot-and-Mouth Disease Virus
分子名称: ACETATE ION, GLYCEROL, RNA-directed RNA polymerase 3D-POL, ...
著者Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E.
登録日2014-11-18
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
3OL7
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Poliovirus polymerase elongation complex with CTP
分子名称: DI(HYDROXYETHYL)ETHER, GLYCEROL, ISOPROPYL ALCOHOL, ...
著者Gong, P, Peersen, O.B.
登録日2010-08-25
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
4WYL
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Mutant K18E of 3D polymerase from Foot-and-Moth Disease Virus
分子名称: ACETATE ION, GLYCEROL, MANGANESE (II) ION, ...
著者Ferrer-Orta, C, Verdaguer, N, de la Higuera, I, Domingo, E.
登録日2014-11-17
公開日2015-05-06
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
1UVJ
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 7nt RNA
分子名称: 5'-R(*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase
著者Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
登録日2004-01-21
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
3OLB
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Poliovirus polymerase elongation complex with 2',3'-dideoxy-ctp
分子名称: 2',3'-DIDEOXYCYTIDINE 5'-TRIPHOSPHATE, ISOPROPYL ALCOHOL, Polymerase, ...
著者Gong, P, Peersen, O.B.
登録日2010-08-25
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.41 Å)
主引用文献Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OL8
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Poliovirus polymerase elongation complex with CTP-Mn
分子名称: GLYCEROL, ISOPROPYL ALCOHOL, MANGANESE (II) ION, ...
著者Gong, P, Peersen, O.B.
登録日2010-08-25
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
3OL6
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Poliovirus polymerase elongation complex
分子名称: ISOPROPYL ALCOHOL, Polymerase, RNA (5'-R(*AP*AP*GP*UP*CP*UP*CP*CP*AP*GP*GP*UP*CP*UP*CP*UP*CP*GP*UP*CP*CP*GP*GP*AP*AP*A)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2010-08-25
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
1RDR
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BU of 1rdr by Molmil
POLIOVIRUS 3D POLYMERASE
分子名称: CALCIUM ION, POLIOVIRUS 3D POLYMERASE
著者Hansen, J, Long, A, Schultz, S.
登録日1998-04-28
公開日1998-09-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structure of the RNA-dependent RNA polymerase of poliovirus.
Structure, 5, 1997
3OLA
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Poliovirus polymerase elongation complex with 2'-deoxy-CTP
分子名称: 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(*GP*CP*CP*CP*GP*GP*AP*CP*GP*AP*GP*AP*GP*A)-D(P*C)-3'), ...
著者Gong, P, Peersen, O.B.
登録日2010-08-25
公開日2010-12-22
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.55 Å)
主引用文献Structural basis for active site closure by the poliovirus RNA-dependent RNA polymerase.
Proc.Natl.Acad.Sci.USA, 107, 2010
4WFX
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BU of 4wfx by Molmil
Coxsackievirus B3 Polymerase - F232L Mutant - NaCl Crystal Form
分子名称: RNA-directed RNA polymerase, SODIUM ION
著者Peersen, O.B, McDonald, S.M.
登録日2014-09-17
公開日2014-10-22
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (1.808 Å)
主引用文献Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases.
J.Virol., 89, 2015
4WZQ
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BU of 4wzq by Molmil
Mutant K20E of RNA dependent RNA polymerase 3D from Foot-and-Mouth disease Virus complexed with RNA
分子名称: MANGANESE (II) ION, RNA dependent-RNA polymerase 3D, RNA template, ...
著者Verdaguer, N, Ferrer-Orta, C.
登録日2014-11-20
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
3NAH
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Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
分子名称: RNA dependent RNA polymerase, SULFATE ION
著者Kim, K.H, Lee, J.H, Alam, I, Park, Y, Kang, S.
登録日2010-06-02
公開日2011-06-08
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Crystal structures and functional analysis of murine norovirus RNA-dependent RNA polymerase
To be Published
4ZPC
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Coxsackievirus B3 Polymerase - A341G mutant
分子名称: RNA-dependent RNA polymerase
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
3NL0
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BU of 3nl0 by Molmil
Mutant P44S M296I of Foot-and-mouth disease Virus RNA-dependent RNA polymerase
分子名称: 3D polymerase, 5'-R(*G*GP*GP*CP*CP*C)-3', 5'-R(P*UP*GP*GP*GP*CP*CP*C)-3', ...
著者Agudo, R, Ferrer-Orta, C, Arias, A, Perez-Luque, R, Verdaguer, N, Domingo, E.
登録日2010-06-21
公開日2011-07-13
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献A multi-step process of viral adaptation to a mutagenic nucleoside analogue by modulation of transition types leads to extinction-escape.
Plos Pathog., 6, 2010
4X2B
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BU of 4x2b by Molmil
K20A RNA dependent RNA polymerase mutant from Foot-and-Mouth disease Virus complexed with an RNA
分子名称: MAGNESIUM ION, RNA dependent RNA polymerase, RNA primer, ...
著者Verdaguer, N, Ferrer-Orta, C.
登録日2014-11-26
公開日2015-05-06
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (2.94 Å)
主引用文献Multifunctionality of a picornavirus polymerase domain: nuclear localization signal and nucleotide recognition.
J.Virol., 89, 2015
1RA6
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BU of 1ra6 by Molmil
Poliovirus Polymerase Full Length Apo Structure
分子名称: ACETIC ACID, Genome polyprotein
著者Thompson, A.A, Peersen, O.B.
登録日2003-10-31
公開日2004-08-17
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural basis for proteolysis-dependent activation of the poliovirus RNA-dependent RNA polymerase.
Embo J., 23, 2004
4ZP7
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Coxsackievirus B3 Polymerase - F364V mutant
分子名称: Genome polyprotein
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.901 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
1UVK
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BU of 1uvk by Molmil
The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 dead-end complex
分子名称: GUANOSINE-5'-MONOPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
登録日2004-01-21
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
4ZPB
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BU of 4zpb by Molmil
Coxsackievirus B3 Polymerase - F364W mutant
分子名称: RNA-directed RNA polymerase
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
1UVM
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 5NT RNA conformation A
分子名称: 5'-R(*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase
著者Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
登録日2004-01-21
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
4ZPD
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Coxsackievirus B3 Polymerase - A345V mutant
分子名称: RNA-directed RNA polymerase
著者Peersen, O.B, McDonald, S.M.
登録日2015-05-07
公開日2016-05-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.797 Å)
主引用文献Design of a Genetically Stable High Fidelity Coxsackievirus B3 Polymerase That Attenuates Virus Growth in Vivo.
J.Biol.Chem., 291, 2016
1UVI
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The structural basis for RNA specificity and Ca2 inhibition of an RNA-dependent RNA polymerase phi6p2 with 6nt RNA
分子名称: 5'-R(*UP*UP*UP*UP*CP*CP)-3', MANGANESE (II) ION, RNA-directed RNA polymerase
著者Salgado, P.S, Makeyev, E.V, Butcher, S, Bamford, D, Stuart, D.I, Grimes, J.M.
登録日2004-01-21
公開日2004-02-19
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献The structural basis for RNA specificity and Ca2+ inhibition of an RNA-dependent RNA polymerase.
Structure, 12, 2004
3N6M
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Crystal structure of EV71 RdRp in complex with GTP
分子名称: GUANOSINE-5'-TRIPHOSPHATE, NICKEL (II) ION, RNA-dependent RNA polymerase
著者Wu, Y, Lou, Z.Y, Miao, Y, Yu, Y, Rao, Z.H.
登録日2010-05-26
公開日2011-06-15
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structures of EV71 RNA-dependent RNA polymerase in complex with substrate and analogue provide a drug target against the hand-foot-and-mouth disease pandemic in China.
Protein Cell, 1, 2010

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件を2024-08-14に公開中

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