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PDB: 248 件

6L4R
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Crystal structure of Enterovirus D68 RdRp
分子名称: RdRp
著者Wang, M.L, Li, L, Zhang, Y, Chen, Y.P, Su, D.
登録日2019-10-21
公開日2020-06-10
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.147 Å)
主引用文献Structure of the enterovirus D68 RNA-dependent RNA polymerase in complex with NADPH implicates an inhibitor binding site in the RNA template tunnel.
J.Struct.Biol., 211, 2020
6LSE
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Crystal structure of the enterovirus 71 polymerase elongation complex (C3S6A/C3S6B form)
分子名称: Genome polyprotein, PYROPHOSPHATE 2-, RNA (35-MER), ...
著者Wang, M, Shu, B, Jing, X, Gong, P.
登録日2020-01-17
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
6LSF
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Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6RA/C2S6RB form)
分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
著者Wang, M, Shu, B, Jing, X, Gong, P.
登録日2020-01-17
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.152 Å)
主引用文献Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
6LSH
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Crystal structure of the enterovirus 71 polymerase elongation complex (C2S6M form)
分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
著者Li, R, Wang, M, Jing, X, Gong, P.
登録日2020-01-17
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.231 Å)
主引用文献Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
6LSG
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Crystal structure of the enterovirus 71 polymerase elongation complex (C0S6M form)
分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
著者Li, R, Wang, M, Jing, X, Gong, P.
登録日2020-01-17
公開日2020-04-29
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Stringent control of the RNA-dependent RNA polymerase translocation revealed by multiple intermediate structures.
Nat Commun, 11, 2020
5F8J
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Enterovirus 71 Polymerase Elongation Complex (C1S4 Form)
分子名称: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
著者Shu, B, Gong, P.
登録日2015-12-09
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.675 Å)
主引用文献Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8L
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Enterovirus 71 Polymerase Elongation Complex (C3S1 Form)
分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*AP*CP*C)-3'), ...
著者Shu, B, Gong, P.
登録日2015-12-09
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.812 Å)
主引用文献Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8I
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Enterovirus 71 Polymerase Elongation Complex (C1S2/3 Form)
分子名称: CYTIDINE-5'-TRIPHOSPHATE, GLYCEROL, Genome polyprotein, ...
著者Shu, B, Gong, P.
登録日2015-12-09
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.503 Å)
主引用文献Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5FJ6
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Structure of the P2 polymerase inside in vitro assembled bacteriophage phi6 polymerase complex
分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Ilca, S, Kotecha, A, Sun, X, Poranen, M.P, Stuart, D.I, Huiskonen, J.T.
登録日2015-10-06
公開日2015-11-04
最終更新日2024-05-08
実験手法ELECTRON MICROSCOPY (7.9 Å)
主引用文献Localized Reconstruction of Subunits from Electron Cryomicroscopy Images of Macromolecular Complexes.
Nat.Commun., 6, 2015
5F8N
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Enterovirus 71 Polymerase Elongation Complex (C3S6 Form)
分子名称: GLYCEROL, Genome polyprotein, PYROPHOSPHATE 2-, ...
著者Shu, B, Gong, P.
登録日2015-12-09
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.484 Å)
主引用文献Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8G
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BU of 5f8g by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S1 Form)
分子名称: Genome polyprotein, RNA (35-MER), RNA (5'-R(*UP*GP*UP*UP*CP*GP*AP*CP*GP*AP*GP*AP*GP*AP*GP*A)-3'), ...
著者Shu, B, Gong, P.
登録日2015-12-09
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.78 Å)
主引用文献Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8M
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Enterovirus 71 Polymerase Elongation Complex (C3S4/5 Form)
分子名称: GLYCEROL, Genome polyprotein, MAGNESIUM ION, ...
著者Shu, B, Gong, P.
登録日2015-12-09
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.83 Å)
主引用文献Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
5F8H
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BU of 5f8h by Molmil
Enterovirus 71 Polymerase Elongation Complex (C1S1/2 Form)
分子名称: Genome polyprotein, MAGNESIUM ION, RNA (35-MER), ...
著者Shu, B, Gong, P.
登録日2015-12-09
公開日2016-06-22
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.45 Å)
主引用文献Structural basis of viral RNA-dependent RNA polymerase catalysis and translocation
Proc.Natl.Acad.Sci.USA, 113, 2016
3UPF
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Crystal structure of murine norovirus RNA-dependent RNA polymerase bound to NF023
分子名称: 8-({3-[({3-[(4,6,8-trisulfonaphthalen-1-yl)carbamoyl]phenyl}carbamoyl)amino]benzoyl}amino)naphthalene-1,3,5-trisulfonic acid, RNA-dependent RNA polymerase, SULFATE ION
著者Milani, M, Mastrangelo, E, Bolognesi, M.
登録日2011-11-18
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
4A8M
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Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*AP*AP*TP*CP)-3', ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.92 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
3UQS
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BU of 3uqs by Molmil
Crystal structures of murine norovirus RNA-dependent RNA polymerase
分子名称: RNA-dependent RNA polymerase, SULFATE ION
著者Milani, M, Mastrangelo, E, Bolognesi, M.
登録日2011-11-21
公開日2012-05-02
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structure-Based Inhibition of Norovirus RNA-Dependent RNA Polymerases.
J.Mol.Biol., 419, 2012
4A8Q
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BU of 4a8q by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*DTP*TP*CP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.06 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8Y
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BU of 4a8y by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.41 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8W
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BU of 4a8w by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*CP*GP*CP*GP*TP*AP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.04 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8F
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BU of 4a8f by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*DAP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8S
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BU of 4a8s by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*TP*TP*TP*TP*CP*GP*CP*GP*TP*AP*GP*CP*GP)-3', ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8K
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BU of 4a8k by Molmil
Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: 5'-D(*AP*AP*TP*CP)-3', 5'-D(*TP*CP)-3', GUANOSINE-5'-TRIPHOSPHATE, ...
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
4A8O
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Non-Catalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial dsRNA virus phi6 from De Novo Initiation to Elongation
分子名称: MANGANESE (II) ION, RNA-DIRECTED RNA POLYMERASE
著者Wright, S, Poranen, M.M, Bamford, D.H, Stuart, D.I, Grimes, J.M.
登録日2011-11-21
公開日2012-07-04
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.67 Å)
主引用文献Noncatalytic Ions Direct the RNA-Dependent RNA Polymerase of Bacterial Double-Stranded RNA Virus Phi6 from De Novo Initiation to Elongation.
J.Virol., 86, 2012
2IM1
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Crystal structure of poliovirus polymerase complexed with CTP and Mn2+
分子名称: ACETIC ACID, CYTIDINE-5'-TRIPHOSPHATE, MANGANESE (II) ION, ...
著者Thompson, A.A, Peersen, O.B.
登録日2006-10-03
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007
2IM3
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Crystal structure of poliovirus polymerase complexed with UTP and Mn2+
分子名称: ACETIC ACID, MANGANESE (II) ION, SODIUM ION, ...
著者Thompson, A.A, Peersen, O.B.
登録日2006-10-03
公開日2006-12-12
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Stabilization of Poliovirus Polymerase by NTP Binding and Fingers-Thumb Interactions.
J.Mol.Biol., 366, 2007

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