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PDB: 511 件

3T32
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Crystal structure of a putative C-S lyase from Bacillus anthracis
分子名称: Aminotransferase, class I/II
著者Anderson, S.M, Wawrzak, Z, Gordon, E, Peterson, S.N, Porebski, P, Minor, W, Savchenko, A, Anderson, W.F, Center for Structural Genomics of Infectious Diseases (CSGID)
登録日2011-07-24
公開日2011-08-10
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Crystal structure of a putative C-S lyase from Bacillus anthracis
TO BE PUBLISHED
6L1L
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Apo-BacF structure from Bacillus subtillis
分子名称: Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Balasubramanian, G, Deshmukh, A.A.
登録日2019-09-29
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Acta Crystallogr.,Sect.F, 76, 2020
6L1N
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Substrate bound BacF structure from Bacillus subtillis
分子名称: Aminotransferase, GLYCINE, PYRIDOXAL-5'-PHOSPHATE
著者Balasubramanian, G, Deshmukh, A.A.
登録日2019-09-29
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Acta Crystallogr.,Sect.F, 76, 2020
6L1O
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Product bound BacF structure from Bacillus subtillis
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, Aminotransferase, PYRIDOXAL-5'-PHOSPHATE, ...
著者Balasubramanian, G, Deshmukh, A.A.
登録日2019-09-29
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural insights into the catalytic mechanism of Bacillus subtilis BacF.
Acta Crystallogr.,Sect.F, 76, 2020
6LIG
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Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) in complex with AH
分子名称: 3-[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]-5-[[3-(3-methylbut-2-enyl)-4-oxidanyl-phenyl]methylidene]-4-oxidanyl-furan-2-one, Glutamate oxaloacetate transaminase 1, PYRIDOXAL-5'-PHOSPHATE
著者Yan, S, Sun, W.G, Zhang, Y.H.
登録日2019-12-10
公開日2020-12-16
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (2.62 Å)
主引用文献Crystal structure of human Glutamate oxaloacetate transaminase 1 (GOT1) in complex with AH
To Be Published
3ZZJ
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Structure of an engineered aspartate aminotransferase
分子名称: ASPARTATE AMINOTRANSFERASE, BETA-MERCAPTOETHANOL, DI(HYDROXYETHYL)ETHER, ...
著者Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C.
登録日2011-09-01
公開日2011-12-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold.
Biocim.Biophys.Acta, 1824, 2011
8JUJ
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Crystal structures of Cystathionine beta lyase from Bacillus cereus ATCC 14579
分子名称: Aspartate aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Yu, H, Kim, K.-J.
登録日2023-06-26
公開日2024-07-03
実験手法X-RAY DIFFRACTION (1.99 Å)
主引用文献Crystal structures of Cystathionine beta lyase from Bacillus cereus ATCC 14579
To Be Published
3TAT
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TYROSINE AMINOTRANSFERASE FROM E. COLI
分子名称: PYRIDOXAL-5'-PHOSPHATE, TYROSINE AMINOTRANSFERASE
著者Ko, T.P, Yang, W.Z, Wu, S.P, Tsai, H, Yuan, H.S.
登録日1998-08-12
公開日1999-08-12
最終更新日2023-08-09
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Crystallization and preliminary crystallographic analysis of the Escherichia coli tyrosine aminotransferase.
Acta Crystallogr.,Sect.D, 55, 1999
4CVQ
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CRYSTAL STRUCTURE OF AN AMINOTRANSFERASE FROM ESCHERICHIA COLI AT 2. 11 ANGSTROEM RESOLUTION
分子名称: ACETATE ION, GLUTAMATE-PYRUVATE AMINOTRANSFERASE ALAA, GLYCEROL, ...
著者Penya-Soler, E, Fernandez, F.J, Lopez-Estepa, M, Garces, F, Richardson, A.J, Rudd, K.E, Coll, M, Vega, M.C.
登録日2014-03-28
公開日2014-07-23
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.11 Å)
主引用文献Structural analysis and mutant growth properties reveal distinctive enzymatic and cellular roles for the three major L-alanine transaminases of Escherichia coli.
PLoS ONE, 9, 2014
3ZZK
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Structure of an engineered aspartate aminotransferase
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ASPARTATE AMINOTRANSFERASE, GLYCEROL, ...
著者Fernandez, F.J, deVries, D, Pena-Soler, E, Coll, M, Christen, P, Gehring, H, Vega, M.C.
登録日2011-09-01
公開日2011-12-28
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure and Mechanism of a Cysteine Sulfinate Desulfinase Engineered on the Aspartate Aminotransferase Scaffold.
Biocim.Biophys.Acta, 1824, 2011
3UE8
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Kynurenine Aminotransferase II Inhibitors
分子名称: (5-hydroxy-4-{[(1-hydroxy-2-oxo-1,2-dihydroquinolin-3-yl)amino]methyl}-6-methylpyridin-3-yl)methyl dihydrogen phosphate, CHLORIDE ION, Kynurenine/alpha-aminoadipate aminotransferase, ...
著者Dounay, A.B, Anderson, M, Bechle, B.M, Campbell, B.M, Claffey, M.M, Evdokimov, A, Edelweiss, E, Fonseca, K.R, Gan, X, Ghosh, S, Hayward, M.M, Horner, W, Kim, J.Y, McAllister, L.A, Pandit, J, Paradis, V, Parikh, V.D, Reese, M.R, Rong, S.B, Salafia, M.A, Schuyten, K, Strick, C.A, Tuttle, J.B, Valentine, J, Wang, H, Zawadzke, L.E, Verhoest, P.R.
登録日2011-10-28
公開日2012-02-01
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.22 Å)
主引用文献Discovery of Brain-Penetrant, Irreversible Kynurenine Aminotransferase II Inhibitors for Schizophrenia.
ACS Med Chem Lett, 3, 2012
3TQX
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Structure of the 2-amino-3-ketobutyrate coenzyme A ligase (kbl) from Coxiella burnetii
分子名称: 2-amino-3-ketobutyrate coenzyme A ligase, PYRIDOXAL-5'-PHOSPHATE
著者Cheung, J, Franklin, M.C, Rudolph, M, Cassidy, M, Gary, E, Burshteyn, F, Love, J.
登録日2011-09-09
公開日2011-09-21
最終更新日2023-12-06
実験手法X-RAY DIFFRACTION (2.304 Å)
主引用文献Structural genomics for drug design against the pathogen Coxiella burnetii.
Proteins, 83, 2015
4DBC
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Substrate Activation in Aspartate Aminotransferase
分子名称: (E)-N-{2-hydroxy-3-methyl-6-[(phosphonooxy)methyl]benzylidene}-L-aspartic acid, 1,2-ETHANEDIOL, Aspartate aminotransferase, ...
著者Toney, M.D, Fisher, A.J, Griswold, W.R.
登録日2012-01-14
公開日2012-12-05
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Ground-state electronic destabilization via hyperconjugation in aspartate aminotransferase.
J.Am.Chem.Soc., 134, 2012
3WX9
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Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, GLA, 4AD, 2OG, GLU and KYA
分子名称: (2E)-pent-2-enedioic acid, 2-OXOGLUTARIC ACID, 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, ...
著者Okada, K, Angkawidjaja, C, Koga, Y, Kanaya, S.
登録日2014-07-28
公開日2014-09-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Crystal structure of Pyrococcus horikoshii kynurenine aminotransferase in complex with PMP, GLA, 4AD, 2OG, GLU and KYA
To be Published
3WZF
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Crystal structure of human cytoplasmic aspartate aminotransferase
分子名称: Aspartate aminotransferase, cytoplasmic
著者Jiang, X, Chang, H, Zhou, Y, Chen, L, Yang, Q.
登録日2014-09-24
公開日2015-10-07
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (2.991 Å)
主引用文献Recombinant expression, purification and Preliminary crystallographic studies of human cytoplasmic aspartate aminotransferase
To be Published
1M7Y
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Crystal structure of apple ACC synthase in complex with L-aminoethoxyvinylglycine
分子名称: (2E,3E)-4-(2-aminoethoxy)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]but-3-enoic acid, (4R)-2-METHYLPENTANE-2,4-DIOL, 1-aminocyclopropane-1-carboxylate synthase
著者Capitani, G, McCarthy, D, Gut, H, Gruetter, M.G, Kirsch, J.F.
登録日2002-07-23
公開日2002-12-23
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Apple 1-Aminocyclopropane-1-carboxylate Synthase in Complex with the Inhibitor L-Aminoethoxyvinylglycine
J.Biol.Chem., 277, 2002
1M4N
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CRYSTAL STRUCTURE OF APPLE ACC SYNTHASE IN COMPLEX WITH [2-(AMINO-OXY)ETHYL](5'-DEOXYADENOSIN-5'-YL)(METHYL)SULFONIUM
分子名称: (2-AMINOOXY-ETHYL)-[5-(6-AMINO-PURIN-9-YL)-3,4-DIHYDROXY-TETRAHYDRO-FURAN-2-YLMETHYL]-METHYL-SULFONIUM, 1-aminocyclopropane-1-carboxylate synthase, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Capitani, G, Eliot, A.C, Gut, H, Khomutov, R.M, Kirsch, J.F, Grutter, M.G.
登録日2002-07-03
公開日2003-04-22
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Structure of 1-aminocyclopropane-1-carboxylate synthase in complex with an amino-oxy analogue of the substrate: implications for substrate binding.
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1647, 2003
8TN3
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Structure of S. hygroscopicus aminotransferase MppQ complexed with pyridoxamine 5'-phosphate (PMP)
分子名称: 4'-DEOXY-4'-AMINOPYRIDOXAL-5'-PHOSPHATE, PLP-dependent aminotransferase MppQ
著者Silvaggi, N.R, Vuksanovic, N.
登録日2023-08-01
公開日2023-11-22
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Structural and Biochemical Characterization of MppQ, an L-Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus.
Biochemistry, 62, 2023
8TN2
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Structure of S. hygroscopicus aminotransferase MppQ complexed with pyridoxal-5'-phosphate (PLP)
分子名称: PLP-dependent aminotransferase MppQ
著者Silvaggi, N.R, Vuksanovic, N.
登録日2023-08-01
公開日2023-11-22
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Structural and Biochemical Characterization of MppQ, an L-Enduracididine Biosynthetic Enzyme from Streptomyces hygroscopicus.
Biochemistry, 62, 2023
1LC8
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Crystal Structure of L-Threonine-O-3-phosphate Decarboxylase from S. enterica complexed with its reaction intermediate
分子名称: L-Threonine-O-3-Phosphate Decarboxylase, {3-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYL)-AMINO]-2-METHYL-PROPYL}-PHOSPHONIC ACID
著者Cheong, C.-G, Escalante-Semerena, J, Rayment, I.
登録日2002-04-05
公開日2002-06-28
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural studies of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica: the apo, substrate, and product-aldimine complexes.
Biochemistry, 41, 2002
1MAP
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CRYSTAL STRUCTURES OF TRUE ENZYMATIC REACTION INTERMEDIATES: ASPARTATE AND GLUTAMATE KETIMINES IN ASPARTATE AMINOTRANSFERASE
分子名称: 2-[(3-HYDROXY-2-METHYL-5-PHOSPHONOOXYMETHYL-PYRIDIN-4-YLMETHYLENE)-AMINO]-SUCCINIC ACID, ASPARTATE AMINOTRANSFERASE
著者Malashkevich, V.N, Jansonius, J.N.
登録日1993-09-10
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Crystal structures of true enzymatic reaction intermediates: aspartate and glutamate ketimines in aspartate aminotransferase.
Biochemistry, 32, 1993
8WKJ
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The crystal structure of aspartate aminotransferases Lpg0070 from Legionella pneumophila
分子名称: Aminotransferase, PYRIDOXAL-5'-PHOSPHATE
著者Gao, Y.S, Hua, L, Xie, R.
登録日2023-09-27
公開日2023-12-06
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Crystal structure of an aspartate aminotransferase Lpg0070 from Legionella pneumophila.
Biochem.Biophys.Res.Commun., 689, 2023
8WOU
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The crystal structure of aspartate aminotransferases Lpg0070 from Legionella pneumophila
分子名称: Aminotransferase, SULFATE ION
著者Gao, Y.S, Hua, L, Xie, R.
登録日2023-10-07
公開日2023-12-06
実験手法X-RAY DIFFRACTION (2.14 Å)
主引用文献Crystal structure of an aspartate aminotransferase Lpg0070 from Legionella pneumophila.
Biochem.Biophys.Res.Commun., 689, 2023
8XHA
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Crystal structure of alpha-Oxoamine Synthase Alb29 with PLP cofactor and L-glutamate
分子名称: 8-amino-7-oxononanoate synthase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE
著者Xu, M.J, Zhang, D.K.
登録日2023-12-17
公開日2024-05-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.27 Å)
主引用文献Structural and mechanistic investigations on CC bond forming alpha-oxoamine synthase allowing L-glutamate as substrate.
Int.J.Biol.Macromol., 268, 2024
8XHD
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Crystal structure of alpha-Oxoamine Synthase Alb29 with PLP cofactor and L-glutamate
分子名称: 8-amino-7-oxononanoate synthase, N-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)-L-glutamic acid, PYRIDOXAL-5'-PHOSPHATE
著者Xu, M.J, Zhang, D.K.
登録日2023-12-17
公開日2024-05-01
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural and mechanistic investigations on CC bond forming alpha-oxoamine synthase allowing L-glutamate as substrate.
Int.J.Biol.Macromol., 268, 2024

223532

件を2024-08-07に公開中

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