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PDB: 516 件

7XJ4
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BU of 7xj4 by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
分子名称: MANGANESE (II) ION, Reverse Transcriptase RNase H domain, S-[5-[(E)-2-phenylethenyl]-1,3,4-oxadiazol-2-yl] 5-nitrothiophene-2-carbothioate, ...
著者Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T.
登録日2022-04-15
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.
J.Chem.Inf.Model., 62, 2022
7XIT
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BU of 7xit by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
分子名称: MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ZINC ION, ...
著者Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T.
登録日2022-04-14
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.18 Å)
主引用文献Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.
J.Chem.Inf.Model., 62, 2022
7XJ7
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BU of 7xj7 by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
分子名称: MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ZINC ION, ...
著者Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T.
登録日2022-04-15
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.
J.Chem.Inf.Model., 62, 2022
7XIS
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BU of 7xis by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
分子名称: (2-methoxy-4-methoxycarbonyl-phenyl) 5-nitrofuran-2-carboxylate, MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ...
著者Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T.
登録日2022-04-14
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.88 Å)
主引用文献Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.
J.Chem.Inf.Model., 62, 2022
7XIU
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BU of 7xiu by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
分子名称: MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ZINC ION, ...
著者Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T.
登録日2022-04-14
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2.09 Å)
主引用文献Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.
J.Chem.Inf.Model., 62, 2022
7XJ5
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BU of 7xj5 by Molmil
Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with nitrofuran methoxy(methoxycarbonyl)phenyl ester
分子名称: MANGANESE (II) ION, Reverse Transcriptase RNase H domain, ZINC ION, ...
著者Lu, H, Komukai, Y, Usami, K, Guo, Y, Qiao, X, Nukaga, M, Hoshino, T.
登録日2022-04-15
公開日2022-04-27
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Computational and Crystallographic Analysis of Binding Structures of Inhibitory Compounds for HIV-1 RNase H Activity.
J.Chem.Inf.Model., 62, 2022
7VSC
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BU of 7vsc by Molmil
E. coli Ribonuclease HI in complex with one Mg2+ (1)
分子名称: MAGNESIUM ION, Ribonuclease HI, SULFATE ION
著者Liao, Z, Oyama, T.
登録日2021-10-26
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.83 Å)
主引用文献Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography.
Acta Crystallogr D Struct Biol, 78, 2022
7VSA
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BU of 7vsa by Molmil
E. coli Ribonuclease HI in complex with two Mg2+
分子名称: GLYCEROL, MAGNESIUM ION, Ribonuclease HI, ...
著者Liao, Z, Oyama, T.
登録日2021-10-26
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography.
Acta Crystallogr D Struct Biol, 78, 2022
7VSB
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BU of 7vsb by Molmil
E. coli Ribonuclease HI in complex with one Zn2+ (His124 N-delta binding)
分子名称: Ribonuclease HI, ZINC ION
著者Liao, Z, Oyama, T.
登録日2021-10-26
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.84 Å)
主引用文献Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography.
Acta Crystallogr D Struct Biol, 78, 2022
7VSD
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BU of 7vsd by Molmil
E. coli Ribonuclease HI in complex with one Mg2+ (2)
分子名称: MAGNESIUM ION, Ribonuclease HI, SULFATE ION
著者Liao, Z, Oyama, T.
登録日2021-10-26
公開日2022-03-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Pivotal role of a conserved histidine in Escherichia coli ribonuclease HI as proposed by X-ray crystallography.
Acta Crystallogr D Struct Biol, 78, 2022
2HB5
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BU of 2hb5 by Molmil
Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain
分子名称: MAGNESIUM ION, Reverse transcriptase/ribonuclease H, SULFATE ION
著者Lim, D, Gregorio, G.G, Bingman, C.A, Martinez-Hackert, E, Hendrickson, W.A, Goff, S.P.
登録日2006-06-13
公開日2006-08-29
最終更新日2023-03-22
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献Crystal Structure of the Moloney Murine Leukemia Virus RNase H Domain.
J.Virol., 80, 2006
4QAG
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BU of 4qag by Molmil
Structure of a dihydroxycoumarin active-site inhibitor in complex with the RNASE H domain of HIV-1 reverse transcriptase
分子名称: (7,8-dihydroxy-2-oxo-2H-chromen-4-yl)acetic acid, MANGANESE (II) ION, Reverse transcriptase/ribonuclease H
著者Himmel, D.M, Ho, W.C, Arnold, E.
登録日2014-05-04
公開日2014-06-04
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.712 Å)
主引用文献Structure of a Dihydroxycoumarin Active-Site Inhibitor in Complex with the RNase H Domain of HIV-1 Reverse Transcriptase and Structure-Activity Analysis of Inhibitor Analogs.
J.Mol.Biol., 426, 2014
2KW4
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BU of 2kw4 by Molmil
Solution NMR Structure of the Holo Form of a Ribonuclease H domain from D.hafniense, Northeast Structural Genomics Consortium Target DhR1A
分子名称: MAGNESIUM ION, Uncharacterized protein
著者Mills, J.L, Eletsky, A, Hua, J, Belote, R.L, Buchwald, W.A, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2010-03-31
公開日2010-05-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Northeast Structural Genomics Consortium Target DhR1A
To be Published
2KQ2
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BU of 2kq2 by Molmil
Solution NMR structure of the apo form of a ribonuclease H domain of protein DSY1790 from Desulfitobacterium hafniense, Northeast Structural Genomics target DhR1A
分子名称: Ribonuclease H-related protein
著者Mills, J.L, Eletsky, A, Hua, J, Belote, R.L, Buchwald, W.A, Ciccosanti, C, Janjua, H, Nair, R, Rost, B, Acton, T.B, Xiao, R, Everett, J.K, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
登録日2009-10-24
公開日2010-03-16
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Solution NMR structure of the apo form of a ribonuclease H domain of protein DSY1790 from Desulfitobacterium hafniense, Northeast Structural Genomics target DhR1A
To be Published
1O1W
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BU of 1o1w by Molmil
SOLUTION STRUCTURE OF THE RNASE H DOMAIN OF THE HIV-1 REVERSE TRANSCRIPTASE IN THE PRESENCE OF MAGNESIUM
分子名称: RIBONUCLEASE H
著者Pari, K, Mueller, G.A, Derose, E.F, Kirby, T.W, London, R.E.
登録日2003-02-12
公開日2003-02-18
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structure of the Rnase H Domain of the HIV-1 Reverse Transcriptase in the Presence of Magnesium
Biochemistry, 42, 2003
1RDB
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BU of 1rdb by Molmil
CRYSTAL STRUCTURES OF RIBONUCLEASE HI ACTIVE SITE MUTANTS FROM ESCHERICHIA COLI
分子名称: RIBONUCLEASE H
著者Katayanagi, K, Morikawa, K.
登録日1993-06-23
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Crystal structures of ribonuclease HI active site mutants from Escherichia coli.
J.Biol.Chem., 268, 1993
1RIL
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BU of 1ril by Molmil
CRYSTAL STRUCTURE OF RIBONUCLEASE H FROM THERMUS THERMOPHILUS HB8 REFINED AT 2.8 ANGSTROMS RESOLUTION
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Okumura, M, Katayanagi, K, Kimura, S, Kanaya, S, Nakamura, H, Morikawa, K.
登録日1993-01-14
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of ribonuclease H from Thermus thermophilus HB8 refined at 2.8 A resolution.
J.Mol.Biol., 230, 1993
1RBS
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BU of 1rbs by Molmil
STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Kanaya, S, Morikawa, K, Nakamura, H.
登録日1993-02-16
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural study of mutants of Escherichia coli ribonuclease HI with enhanced thermostability.
Protein Eng., 6, 1993
1RDH
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BU of 1rdh by Molmil
CRYSTALLOGRAPHIC ANALYSES OF AN ACTIVE HIV-1 RIBONUCLEASE H DOMAIN SHOW STRUCTURAL FEATURES THAT DISTINGUISH IT FROM THE INACTIVE FORM
分子名称: HIV-1 REVERSE TRANSCRIPTASE (RIBONUCLEASE H DOMAIN)
著者Finzel, B.C, Chattopadhyay, D, Einspahr, H.M.
登録日1993-03-05
公開日1994-05-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystallographic analyses of an active HIV-1 ribonuclease H domain show structural features that distinguish it from the inactive form.
Acta Crystallogr.,Sect.D, 49, 1993
1RBU
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BU of 1rbu by Molmil
STRUCTURAL STUDY OF MUTANTS OF ESCHERICHIA COLI RIBONUCLEASE HI WITH ENHANCED THERMOSTABILITY
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Kanaya, S, Morikawa, K, Nakamura, H.
登録日1993-02-16
公開日1994-01-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural study of mutants of Escherichia coli ribonuclease HI with enhanced thermostability.
Protein Eng., 6, 1993
1RDD
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BU of 1rdd by Molmil
CRYSTAL STRUCTURE OF ESCHERICHIA COLI RNASE HI IN COMPLEX WITH MG2+ AT 2.8 ANGSTROMS RESOLUTION: PROOF FOR A SINGLE MG2+ SITE
分子名称: MAGNESIUM ION, RIBONUCLEASE H
著者Katayanagi, K, Morikawa, K.
登録日1993-06-23
公開日1993-10-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Crystal structure of Escherichia coli RNase HI in complex with Mg2+ at 2.8 A resolution: proof for a single Mg(2+)-binding site.
Proteins, 17, 1993
1F21
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BU of 1f21 by Molmil
DIVALENT METAL COFACTOR BINDING IN THE KINETIC FOLDING TRAJECTORY OF E. COLI RIBONUCLEASE HI
分子名称: RIBONUCLEASE HI
著者Goedken, E.R, Keck, J.L, Berger, J.M, Marqusee, S.
登録日2000-05-22
公開日2000-12-06
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.4 Å)
主引用文献Divalent metal cofactor binding in the kinetic folding trajectory of Escherichia coli ribonuclease HI.
Protein Sci., 9, 2000
1G15
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BU of 1g15 by Molmil
CO-CRYSTAL OF E. COLI RNASE HI WITH TWO MN2+ IONS BOUND IN THE THE ACTIVE SITE
分子名称: MANGANESE (II) ION, RIBONUCLEASE HI
著者Goedken, E.R, Marqusee, S.
登録日2000-10-10
公開日2001-03-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Co-crystal of Escherichia coli RNase HI with Mn2+ ions reveals two divalent metals bound in the active site.
J.Biol.Chem., 276, 2001
1GOB
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BU of 1gob by Molmil
COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993
1GOC
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BU of 1goc by Molmil
COOPERATIVE STABILIZATION OF ESCHERICHIA COLI RIBONUCLEASE HI BY INSERTION OF GLY-80B AND GLY-77-> ALA SUBSTITUTION
分子名称: RIBONUCLEASE H
著者Ishikawa, K, Kimura, S, Nakamura, H, Morikawa, K, Kanaya, S.
登録日1993-05-10
公開日1994-01-31
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Cooperative stabilization of Escherichia coli ribonuclease HI by insertion of Gly-80b and Gly-77-->Ala substitution.
Biochemistry, 32, 1993

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