4Z0U
| RNase HI/SSB-Ct complex | 分子名称: | Ribonuclease H, SSB-Ct Peptide | 著者 | Petzold, C, Keck, J.L. | 登録日 | 2015-03-26 | 公開日 | 2015-04-29 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Interaction with Single-stranded DNA-binding Protein Stimulates Escherichia coli Ribonuclease HI Enzymatic Activity. J.Biol.Chem., 290, 2015
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2QK9
| Human RNase H catalytic domain mutant D210N in complex with 18-mer RNA/DNA hybrid | 分子名称: | 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*GP*CP*AP*CP*T)-3', 5'-R(*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3', CITRATE ANION, ... | 著者 | Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W. | 登録日 | 2007-07-10 | 公開日 | 2007-11-13 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription Mol.Cell, 28, 2007
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1WSI
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2QKB
| Human RNase H catalytic domain mutant D210N in complex with 20-mer RNA/DNA hybrid | 分子名称: | 1,2-ETHANEDIOL, 5'-D(*DGP*DGP*DAP*DAP*DTP*DCP*DAP*DGP*DGP*DTP*DGP*DTP*DCP*DGP*DCP*DAP*DCP*DTP*DCP*DT)-3', 5'-R(*GP*GP*AP*GP*UP*GP*CP*GP*AP*CP*AP*CP*CP*UP*GP*AP*UP*UP*CP*C)-3'), ... | 著者 | Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W. | 登録日 | 2007-07-10 | 公開日 | 2007-11-13 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription Mol.Cell, 28, 2007
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2QKK
| Human RNase H catalytic domain mutant D210N in complex with 14-mer RNA/DNA hybrid | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 5'-D(*GP*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*CP*G)-3', ... | 著者 | Nowotny, M, Gaidamakov, S.A, Ghirlando, R, Cerritelli, S.M, Crouch, R.J, Yang, W. | 登録日 | 2007-07-11 | 公開日 | 2007-11-13 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structure of Human RNase H1 Complexed with an RNA/DNA Hybrid: Insight into HIV Reverse Transcription Mol.Cell, 28, 2007
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1WSJ
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1WSH
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1WSF
| Co-crystal structure of E.coli RNase HI active site mutant (D134A*) with Mn2+ | 分子名称: | MANGANESE (II) ION, Ribonuclease HI | 著者 | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | 登録日 | 2004-11-05 | 公開日 | 2005-02-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography J.Mol.Biol., 345, 2005
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1WSE
| Co-crystal structure of E.coli RNase HI active site mutant (E48A*) with Mn2+ | 分子名称: | MANGANESE (II) ION, Ribonuclease HI | 著者 | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | 登録日 | 2004-11-05 | 公開日 | 2005-02-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography J.Mol.Biol., 345, 2005
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1WSG
| Co-crystal structure of E.coli RNase HI active site mutant (E48A/D134N*) with Mn2+ | 分子名称: | MANGANESE (II) ION, Ribonuclease HI | 著者 | Tsunaka, Y, Takano, K, Matsumura, H, Yamagata, Y, Kanaya, S. | 登録日 | 2004-11-05 | 公開日 | 2005-02-08 | 最終更新日 | 2024-05-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Identification of Single Mn(2+) Binding Sites Required for Activation of the Mutant Proteins of E.coli RNase HI at Glu48 and/or Asp134 by X-ray Crystallography J.Mol.Biol., 345, 2005
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8JYI
| Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid E | 分子名称: | 7-[5-(2-azanylethyl)-2-oxidanyl-phenyl]-3,5,6,8-tetrakis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-1,2-dicarboxylic acid, MANGANESE (II) ION, Pol protein,Pol protein,Ribonuclease H, ... | 著者 | Ito, Y, Lu, H, Kitajima, M, Ishikawa, H, Nakata, Y, Iwatani, Y, Hoshino, T. | 登録日 | 2023-07-03 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase. J.Nat.Prod., 86, 2023
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8JYH
| Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid C | 分子名称: | 7-[5-[(2~{S})-2-azanyl-3-oxidanyl-3-oxidanylidene-propyl]-2-oxidanyl-phenyl]-3,5,6,8-tetrakis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-1,2-dicarboxylic acid, MANGANESE (II) ION, Pol protein,Pol protein,HIV-1 Reverse Transcriptase RNase H active domain, ... | 著者 | Ito, Y, Lu, H, Kitajima, M, Ishikawa, H, Nakata, Y, Iwatani, Y, Hoshino, T. | 登録日 | 2023-07-03 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.21 Å) | 主引用文献 | Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase. J.Nat.Prod., 86, 2023
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8JYJ
| Crystal structure of engineered HIV-1 Reverse Transcriptase RNase H domain complexed with laccaic acid A | 分子名称: | 7-[5-(2-acetamidoethyl)-2-oxidanyl-phenyl]-3,5,6,8-tetrakis(oxidanyl)-9,10-bis(oxidanylidene)anthracene-1,2-dicarboxylic acid, MANGANESE (II) ION, Pol protein,Pol protein,HIV-1 Reverse Transcriptase RNase H active domain, ... | 著者 | Ito, Y, Lu, H, Kitajima, M, Ishikawa, H, Nakata, Y, Iwatani, Y, Hoshino, T. | 登録日 | 2023-07-03 | 公開日 | 2023-08-16 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.01 Å) | 主引用文献 | Sticklac-Derived Natural Compounds Inhibiting RNase H Activity of HIV-1 Reverse Transcriptase. J.Nat.Prod., 86, 2023
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2LSN
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2E4L
| Thermodynamic and Structural Analysis of Thermolabile RNase HI from Shewanella oneidensis MR-1 | 分子名称: | Ribonuclease HI | 著者 | Tadokoro, T, You, D.J, Chon, H, Matsumura, H, Koga, Y, Takano, K, Kanaya, S. | 登録日 | 2006-12-13 | 公開日 | 2007-05-01 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural, thermodynamic, and mutational analyses of a psychrotrophic RNase HI. Biochemistry, 46, 2007
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4E89
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3V1Q
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3V1O
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3V1R
| Crystal structures of the reverse transcriptase-associated ribonuclease H domain of XMRV with inhibitor beta-thujaplicinol | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, 2,7-dihydroxy-4-(propan-2-yl)cyclohepta-2,4,6-trien-1-one, MANGANESE (II) ION, ... | 著者 | Zhou, D, Wlodawer, A. | 登録日 | 2011-12-09 | 公開日 | 2012-03-14 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Crystal structures of the reverse transcriptase-associated ribonuclease H domain of xenotropic murine leukemia-virus related virus. J.Struct.Biol., 177, 2012
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3QIO
| Crystal Structure of HIV-1 RNase H with engineered E. coli loop and N-hydroxy quinazolinedione inhibitor | 分子名称: | 3-hydroxy-6-(phenylsulfonyl)quinazoline-2,4(1H,3H)-dione, Gag-Pol polyprotein,Ribonuclease HI,Gag-Pol polyprotein, MANGANESE (II) ION, ... | 著者 | Lansdon, E.B, Liu, Q. | 登録日 | 2011-01-27 | 公開日 | 2011-04-20 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.4011 Å) | 主引用文献 | Structural and Binding Analysis of Pyrimidinol Carboxylic Acid and N-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors. Antimicrob.Agents Chemother., 55, 2011
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3QIN
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2RN2
| STRUCTURAL DETAILS OF RIBONUCLEASE H FROM ESCHERICHIA COLI AS REFINED TO AN ATOMIC RESOLUTION | 分子名称: | RIBONUCLEASE H | 著者 | Katayanagi, K, Miyagawa, M, Matsushima, M, Ishikawa, M, Kanaya, S, Nakamura, H, Ikehara, M, Matsuzaki, T, Morikawa, K. | 登録日 | 1992-04-15 | 公開日 | 1993-10-31 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (1.48 Å) | 主引用文献 | Structural details of ribonuclease H from Escherichia coli as refined to an atomic resolution. J.Mol.Biol., 223, 1992
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2RPI
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5DZM
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7VSE
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