2CBY
 
 | | Crystal structure of the ATP-dependent Clp Protease proteolytic subunit 1 (ClpP1) from Mycobacterium tuberculosis | | 分子名称: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | | 著者 | Mate, M.J, Portnoi, D, Alzari, P.M, Ortiz-Lombardia, M. | | 登録日 | 2006-01-10 | | 公開日 | 2006-01-11 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
2CE3
 | | CRYSTAL STRUCTURE OF THE ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 (CLPP1) FROM MYCOBACTERIUM TUBERCULOSIS | | 分子名称: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | | 著者 | Segelke, B, Kim, C.Y, Ortiz-Lombardia, M, Alzari, P.M, Lekin, T. | | 登録日 | 2006-02-03 | | 公開日 | 2006-02-09 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
6IW7
 | | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease | | 分子名称: | (2S)-2-benzamido-4-methyl-pentanoic acid, 4-[(4-fluoro-2-methyl-3H-indol-5-yl)oxy]-6-methoxy-7-[3-(pyrrolidin-1-yl)propoxy]quinazoline, ATP-dependent Clp protease proteolytic subunit 1, ... | | 著者 | Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z. | | 登録日 | 2018-12-04 | | 公開日 | 2020-01-01 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2.692121 Å) | | 主引用文献 | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease
To Be Published
|
|
5E0S
 | | crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | | 分子名称: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2 | | 著者 | LI, M, Wlodawer, A, Maurizi, M. | | 登録日 | 2015-09-29 | | 公開日 | 2016-02-17 | | 最終更新日 | 2016-04-13 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
|
|
2C8T
 | | The 3.0 A Resolution Structure of Caseinolytic Clp Protease 1 from Mycobacterium tuberculosis | | 分子名称: | ATP-DEPENDENT CLP PROTEASE PROTEOLYTIC SUBUNIT 1 | | 著者 | Ingvarsson, H, Hogbom, M, Jones, T.A, Unge, T. | | 登録日 | 2005-12-07 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (3 Å) | | 主引用文献 | Insights Into the Inter-Ring Plasticity of Caseinolytic Proteases from the X-Ray Structure of Mycobacterium Tuberculosis Clpp1.
Acta Crystallogr.,Sect.D, 63, 2007
|
|
5DZK
 | | Crystal structure of the active form of the proteolytic complex clpP1 and clpP2 | | 分子名称: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, BEZ-LEU-LEU | | 著者 | LI, M, Wlodawer, A, Maurizi, M. | | 登録日 | 2015-09-25 | | 公開日 | 2016-02-17 | | 最終更新日 | 2016-04-13 | | 実験手法 | X-RAY DIFFRACTION (3.07 Å) | | 主引用文献 | Structure and Functional Properties of the Active Form of the Proteolytic Complex, ClpP1P2, from Mycobacterium tuberculosis.
J.Biol.Chem., 291, 2016
|
|
6VGK
 | | ClpP1P2 complex from M. tuberculosis | | 分子名称: | ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2 | | 著者 | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | | 登録日 | 2020-01-08 | | 公開日 | 2020-03-18 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
6VGN
 | | ClpP1P2 complex from M. tuberculosis bound to ADEP | | 分子名称: | ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, R0M-WFP-ALO-PRO-YCP-ALA-MP8 | | 著者 | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | | 登録日 | 2020-01-08 | | 公開日 | 2020-03-18 | | 最終更新日 | 2020-04-01 | | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | | 主引用文献 | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
4U0G
 | | Crystal Structure of M. tuberculosis ClpP1P2 bound to ADEP and agonist | | 分子名称: | ADEP-2B5Me, ATP-dependent Clp protease proteolytic subunit 1, ATP-dependent Clp protease proteolytic subunit 2, ... | | 著者 | Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T. | | 登録日 | 2014-07-11 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (3.1978 Å) | | 主引用文献 | Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
7X8X
 | | structural insights into Mycobacterium tuberculosis ClpP1P2 inhibition by Cediranib: implications for developing antimicrobial agents targeting Clp protease | | 分子名称: | 4-[1-[3-[4-[(4-fluoranyl-2-methyl-1H-indol-5-yl)oxy]-6-methoxy-quinazolin-7-yl]oxypropyl]piperidin-4-yl]benzamide, 4-[[3,5-bis(fluoranyl)phenyl]methyl]-N-[(4-bromophenyl)methyl]piperazine-1-carboxamide, ATP-dependent Clp protease proteolytic subunit 1, ... | | 著者 | Bao, R, Luo, Y.F, Zhu, Y.B, Yang, Y, Zhou, Y.Z. | | 登録日 | 2022-03-15 | | 公開日 | 2023-04-12 | | 最終更新日 | 2024-04-24 | | 実験手法 | X-RAY DIFFRACTION (3.24 Å) | | 主引用文献 | Discovery and Mechanistic Study of Novel Mycobacterium tuberculosis ClpP1P2 Inhibitors
J.Med.Chem., 66, 2023
|
|
4U0H
 | | Crystal Structure of M. tuberculosis ClpP1P1 | | 分子名称: | ATP-dependent Clp protease proteolytic subunit 1, SULFATE ION | | 著者 | Schmitz, K.R, Carney, D.W, Sello, J.K, Sauer, R.T. | | 登録日 | 2014-07-11 | | 公開日 | 2014-10-08 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (3.2479 Å) | | 主引用文献 | Crystal structure of Mycobacterium tuberculosis ClpP1P2 suggests a model for peptidase activation by AAA+ partner binding and substrate delivery.
Proc.Natl.Acad.Sci.USA, 111, 2014
|
|
6VGQ
 | | ClpP1P2 complex from M. tuberculosis with GLF-CMK bound to ClpP1 | | 分子名称: | ATP-dependent Clp protease proteolytic subunit, ATP-dependent Clp protease proteolytic subunit 1, Z-Gly-leu-phe-CH2Cl | | 著者 | Ripstein, Z.A, Vahidi, S, Rubinstein, J.L, Kay, L.E. | | 登録日 | 2020-01-08 | | 公開日 | 2020-03-18 | | 最終更新日 | 2020-04-01 | | 実験手法 | ELECTRON MICROSCOPY (3.5 Å) | | 主引用文献 | An allosteric switch regulatesMycobacterium tuberculosisClpP1P2 protease function as established by cryo-EM and methyl-TROSY NMR.
Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
