6MPI
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGU-codon in the A-site and paromomycin | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Cantara, W.A, DeMirci, H, Agris, P.F. | 登録日 | 2018-10-07 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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6MPF
| Structure of the Thermus thermophilus 30S ribosomal subunit complexed with a 2-thiocytidine (s2C32) and inosine (I34) modified anticodon stem loop (ASL) of Escherichia coli transfer RNA Arginine 1 (TRNAARG1) bound to an mRNA with an CGC-codon in the A-site and paromomycin | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Cantara, W.A, DeMirci, H, Agris, P.F. | 登録日 | 2018-10-05 | 公開日 | 2019-04-24 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.33 Å) | 主引用文献 | A Structural Basis for Restricted Codon Recognition Mediated by 2-thiocytidine in tRNA Containing a Wobble Position Inosine. J.Mol.Biol., 432, 2020
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5VPO
| The 70S P-site ASL SufA6 complex | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hong, S, Sunita, S, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2017-05-05 | 公開日 | 2018-09-26 | 最終更新日 | 2018-11-07 | 実験手法 | X-RAY DIFFRACTION (3.34 Å) | 主引用文献 | Mechanism of tRNA-mediated +1 ribosomal frameshifting. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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4LF4
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDROXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 16S rRNA, MAGNESIUM ION, ... | 著者 | Demirci, H, Belardinelli, R, Carr, J, Murphy IV, F, Jogl, G, Dahlberg, A.E, Gregory, S.T. | 登録日 | 2013-06-26 | 公開日 | 2014-07-02 | 実験手法 | X-RAY DIFFRACTION (3.3421 Å) | 主引用文献 | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus To be Published, 2013
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4X65
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D. | 登録日 | 2014-12-06 | 公開日 | 2015-11-18 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (3.345 Å) | 主引用文献 | N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat.Struct.Mol.Biol., 23, 2016
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4DR3
| Crystal structure of the Thermus thermophilus (HB8) 30S ribosomal subunit with streptomycin bound | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-16 | 公開日 | 2012-11-14 | 最終更新日 | 2013-01-30 | 実験手法 | X-RAY DIFFRACTION (3.348 Å) | 主引用文献 | A structural basis for streptomycin-induced misreading of the genetic code. Nat Commun, 4, 2013
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4V8X
| Structure of Thermus thermophilus ribosome | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S RIBOSOMAL PROTEIN S10, ... | 著者 | Feng, S, Chen, Y, Kamada, K, Wang, H, Tang, K, Wang, M, Gao, Y.G. | 登録日 | 2013-07-19 | 公開日 | 2014-07-09 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Yoeb-Ribosome Structure: A Canonical Rnase that Requires the Ribosome for its Specific Activity. Nucleic Acids Res., 41, 2013
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1N33
| Structure of the Thermus thermophilus 30S ribosomal subunit bound to codon and near-cognate transfer rna anticodon stem-loop mismatched at the second codon position at the a site with paromomycin | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Ogle, J.M, Murphy IV, F.V, Tarry, M.J, Ramakrishnan, V. | 登録日 | 2002-10-25 | 公開日 | 2002-11-29 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | Selection of tRNA by the Ribosome Requires a Transition from an Open to a Closed Form Cell(Cambridge,Mass.), 111, 2002
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4X64
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | 16S rRNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Demirci, H, Chen, J, Choi, J, Soltis, M, Puglisi, J.D. | 登録日 | 2014-12-06 | 公開日 | 2015-11-18 | 最終更新日 | 2019-12-25 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | N(6)-methyladenosine in mRNA disrupts tRNA selection and translation-elongation dynamics. Nat.Struct.Mol.Biol., 23, 2016
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2HHH
| Crystal structure of kasugamycin bound to the 30S ribosomal subunit | 分子名称: | (1S,2R,3S,4R,5S,6S)-2,3,4,5,6-PENTAHYDROXYCYCLOHEXYL 2-AMINO-4-{[CARBOXY(IMINO)METHYL]AMINO}-2,3,4,6-TETRADEOXY-ALPHA-D-ARABINO-HEXOPYRANOSIDE, 16S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Schluenzen, F. | 登録日 | 2006-06-28 | 公開日 | 2006-09-26 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | The antibiotic kasugamycin mimics mRNA nucleotides to destabilize tRNA binding and inhibit canonical translation initiation. Nat.Struct.Mol.Biol., 13, 2006
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4JI3
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | 16S rRNA, MAGNESIUM ION, RIBOSOMAL PROTEIN S10, ... | 著者 | Demirci, H, Wang, L, Murphy, F.V, Murphy, E.L, Carr, J, Blanchard, S, Jogl, G, Dahlberg, A.E, Gregory, S.T. | 登録日 | 2013-03-05 | 公開日 | 2013-11-06 | 最終更新日 | 2024-02-28 | 実験手法 | X-RAY DIFFRACTION (3.35 Å) | 主引用文献 | The central role of protein S12 in organizing the structure of the decoding site of the ribosome. Rna, 19, 2013
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6GSK
| Structure of T. thermophilus 70S ribosome complex with mRNA, tRNAfMet and near-cognate tRNAThr in the A-site | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rozov, A, Yusupov, M, Yusupova, G. | 登録日 | 2018-06-14 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (3.36 Å) | 主引用文献 | Tautomeric G•U pairs within the molecular ribosomal grip and fidelity of decoding in bacteria. Nucleic Acids Res., 46, 2018
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4DUY
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit with a 16S rRNA mutation, U13C | 分子名称: | 16S rRNA, MAGNESIUM ION, ZINC ION, ... | 著者 | Demirci, H, Murphy IV, F, Murphy, E, Gregory, S.T, Dahlberg, A.E, Jogl, G. | 登録日 | 2012-02-22 | 公開日 | 2013-02-27 | 実験手法 | X-RAY DIFFRACTION (3.386 Å) | 主引用文献 | A structural basis for streptomycin resistance To be Published
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6NSH
| Modified ASL proline bound to Thermus thermophilus 70S (near-cognate) | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Hoffer, E.D, Maehigashi, T, Subaramanian, S, Hong, S, Dunham, C.M. | 登録日 | 2019-01-24 | 公開日 | 2020-10-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (3.397 Å) | 主引用文献 | Structural insights into mRNA reading frame regulation by tRNA modification and slippery codon-anticodon pairing. Elife, 9, 2020
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4WT8
| Crystal Structure of bactobolin A bound to 70S ribosome-tRNA complex | 分子名称: | 23S rRNA (2899-MER), 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Amunts, A, Fiedorczuk, K, Ramakrishnan, V. | 登録日 | 2014-10-29 | 公開日 | 2015-01-21 | 最終更新日 | 2018-07-18 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Bactobolin A Binds to a Site on the 70S Ribosome Distinct from Previously Seen Antibiotics. J.Mol.Biol., 427, 2015
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7V2M
| T.thermophilus 30S ribosome with KsgA, class K1k4 | 分子名称: | 16s ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Raina, R, Singh, J, Anand, R, Vinothkumar, K.R. | 登録日 | 2021-08-09 | 公開日 | 2022-04-06 | 最終更新日 | 2024-06-12 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Decoding the Mechanism of Specific RNA Targeting by Ribosomal Methyltransferases. Acs Chem.Biol., 17, 2022
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5WNU
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus | 分子名称: | (1R,2S,3S,4R,6R)-4,6-diamino-2-{[3-O-(2,6-diamino-2,6-dideoxy-alpha-L-altropyranosyl)-beta-L-arabinofuranosyl]oxy}-3-hydroxycyclohexyl 2-amino-2-deoxy-alpha-D-allopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | 著者 | DeMirci, H. | 登録日 | 2017-08-01 | 公開日 | 2018-02-21 | 最終更新日 | 2020-10-21 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | 2'-O-methylation in mRNA disrupts tRNA decoding during translation elongation. Nat. Struct. Mol. Biol., 25, 2018
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1HNX
| STRUCTURE OF THE THERMUS THERMOPHILUS 30S RIBOSOMAL SUBUNIT IN COMPLEX WITH PACTAMYCIN | 分子名称: | 16S RIBOSOMAL RNA, 30S RIBOSOMAL PROTEIN S10, 30S RIBOSOMAL PROTEIN S11, ... | 著者 | Brodersen, D.E, Clemons Jr, W.M, Carter, A.P, Morgan-Warren, R, Wimberly, B.T, Ramakrishnan, V. | 登録日 | 2000-12-08 | 公開日 | 2001-02-21 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | The structural basis for the action of the antibiotics tetracycline, pactamycin, and hygromycin B on the 30S ribosomal subunit. Cell(Cambridge,Mass.), 103, 2000
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6B4V
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6CAP
| Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin | 分子名称: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | 著者 | DeMirci, H. | 登録日 | 2018-01-31 | 公開日 | 2018-07-25 | 最終更新日 | 2020-10-21 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin To Be Published
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6CAR
| Serial Femtosecond X-ray Crystal Structure of 30S ribosomal subunit from Thermus thermophilus in complex with Sisomicin | 分子名称: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, 16S Ribosomal RNA rRNA, 30S ribosomal protein S10, ... | 著者 | DeMirci, H. | 登録日 | 2018-01-31 | 公開日 | 2018-07-25 | 最終更新日 | 2018-10-24 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Aminoglycoside ribosome interactions reveal novel conformational states at ambient temperature. Nucleic Acids Res., 46, 2018
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4K0K
| Crystal structure of the Thermus thermophilus 30S ribosomal subunit complexed with a serine-ASL and mRNA containing a stop codon | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Fernandez, I.S, Ng, C.L, Kelley, A.C, Guowei, W, Yu, Y.T, Ramakrishnan, V. | 登録日 | 2013-04-04 | 公開日 | 2013-06-26 | 最終更新日 | 2013-08-21 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Unusual base pairing during the decoding of a stop codon by the ribosome. Nature, 500, 2013
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5BR8
| Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin | 分子名称: | 16S ribosomal RNA, 30S ribosomal protein S10, 30S ribosomal protein S11, ... | 著者 | Sierra, R.G, Gati, C, Laksmono, H, Dao, E.H, Gul, S, Fuller, F, Kern, J, Chatterjee, R, Ibrahim, M, Brewster, A, Young, I.D, Michels-Clark, T, Aquila, A, Mengning, L, Hunter, M.S, Koglin, J.E, Boutet, S, Junco, E.A, Hayes, B, Bogan, M.J, Hampton, C.Y, Puglisi, E.V, Sauter, N.K, Stan, C.A, Zouni, A, Yano, J, Yachandra, V.K, Soltis, S.M, Puglisi, J.D, DeMirci, H. | 登録日 | 2015-05-29 | 公開日 | 2015-11-18 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Ambient-temperature crystal structure of 30S ribosomal subunit from Thermus thermophilus in complex with paromomycin To Be Published
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4YPB
| Precleavage 70S structure of the P. vulgaris HigB DeltaH92 toxin bound to the AAA codon | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Schureck, M.A, Dunkle, J.A, Maehigashi, T, Dunham, C.M. | 登録日 | 2015-03-12 | 公開日 | 2015-10-21 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.4 Å) | 主引用文献 | Defining the mRNA recognition signature of a bacterial toxin protein. Proc.Natl.Acad.Sci.USA, 112, 2015
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6CAQ
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