8J6Y
 
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8DE2
 | | TEM-1 beta-lactamase A237Y mutant covalently bound to avibactam, a room temperature structure | | 分子名称: | (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase TEM | | 著者 | Ji, Z, Boxer, S.G, Mathews, I.I. | | 登録日 | 2022-06-19 | | 公開日 | 2022-09-07 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.45 Å) | | 主引用文献 | Protein Electric Fields Enable Faster and Longer-Lasting Covalent Inhibition of beta-Lactamases.
J.Am.Chem.Soc., 144, 2022
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7QNK
 | | Structure of beta-lactamase TEM-171 complexed with tazobactam intermediate at 2.5 A resolution | | 分子名称: | ACETATE ION, Beta-lactamase TEM, TAZOBACTAM INTERMEDIATE | | 著者 | Hakanpaa, J, Petrova, T, Samygina, V.R, Lamzin, V.S, Egorov, A.M. | | 登録日 | 2021-12-21 | | 公開日 | 2022-07-13 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Crystal structures of the molecular class A beta-lactamase TEM-171 and its complexes with tazobactam.
Acta Crystallogr D Struct Biol, 78, 2022
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4IBX
 | | Crystal structure of stabilized TEM-1 beta-lactamase variant v.13 | | 分子名称: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Beta-lactamase TEM, CALCIUM ION, ... | | 著者 | Dellus-Gur, E, Toth-Petroczy, A, Elias, M, Tawfik, D.S. | | 登録日 | 2012-12-09 | | 公開日 | 2013-04-03 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | | 主引用文献 | What Makes a Protein Fold Amenable to Functional Innovation? Fold Polarity and Stability Trade-offs.
J.Mol.Biol., 425, 2013
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3JYI
 | | Structural and biochemical evidence that a TEM-1 {beta}-lactamase Asn170Gly active site mutant acts via substrate-assisted catalysis | | 分子名称: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Beta-lactamase TEM, PHOSPHATE ION | | 著者 | Brown, N.G, Palzkill, T.G, Prasad, B.V.V, Shanker, S. | | 登録日 | 2009-09-21 | | 公開日 | 2009-10-06 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | | 主引用文献 | Structural and biochemical evidence that a TEM-1 beta-lactamase N170G active site mutant acts via substrate-assisted catalysis
J.Biol.Chem., 284, 2009
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