7QNK

Structure of beta-lactamase TEM-171 complexed with tazobactam intermediate at 2.5 A resolution

Summary for 7QNK

Entry DOI	10.2210/pdb7qnk/pdb
Related	7QLP
Descriptor	Beta-lactamase TEM, TAZOBACTAM INTERMEDIATE, ACETATE ION, ... (4 entities in total)
Functional Keywords	beta-lactamase, beta-lactamase inhibitor, hydrolase-inhibitor complex, hydrolase
Biological source	Escherichia coli
Total number of polymer chains	6
Total formula weight	175365.75
Authors	Hakanpaa, J.,Petrova, T.,Samygina, V.R.,Lamzin, V.S.,Egorov, A.M. (deposition date: 2021-12-21, release date: 2022-07-13, Last modification date: 2024-01-31)
Primary citation	Grigorenko, V.G.,Petrova, T.E.,Carolan, C.,Rubtsova, M.Y.,Uporov, I.V.,Pereira, J.,Chojnowski, G.,Samygina, V.R.,Lamzin, V.S.,Egorov, A.M. Crystal structures of the molecular class A beta-lactamase TEM-171 and its complexes with tazobactam. Acta Crystallogr D Struct Biol, 78:825-834, 2022 Cited by PubMed: 35775982 DOI: 10.1107/S2059798322004879 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.5 Å)

Structure validation