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PDB: 166 件

5V7M
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PCNA mutant L126A/I128A Protein Defective in Gene Silencing
分子名称: MAGNESIUM ION, Proliferating cell nuclear antigen
著者Kondratick, C.M, Litman, J.M, Washington, M.T, Dieckman, L.M.
登録日2017-03-20
公開日2018-03-14
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.93 Å)
主引用文献Crystal structures of PCNA mutant proteins defective in gene silencing suggest a novel interaction site on the front face of the PCNA ring.
PLoS ONE, 13, 2018
8CCS
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BU of 8ccs by Molmil
80S S. cerevisiae ribosome with ligands in hybrid-1 pre-translocation (PRE-H1) complex
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
登録日2023-01-27
公開日2023-09-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (1.97 Å)
主引用文献mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
6ZQH
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Yeast Uba1 in complex with ubiquitin
分子名称: BETA-MERCAPTOETHANOL, GLYCEROL, TETRAETHYLENE GLYCOL, ...
著者Misra, M, Schindelin, H.
登録日2020-07-09
公開日2020-11-04
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.032 Å)
主引用文献Development of ADPribosyl Ubiquitin Analogues to Study Enzymes Involved in Legionella Infection.
Chemistry, 27, 2021
8CDR
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BU of 8cdr by Molmil
Translocation intermediate 2 (TI-2) of 80S S. cerevisiae ribosome with ligands and eEF2 in the presence of sordarin
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
登録日2023-01-31
公開日2023-09-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.04 Å)
主引用文献mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024
8DQX
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BU of 8dqx by Molmil
Open state of RFC:PCNA bound to a 3' ss/dsDNA junction
分子名称: DNA (5'-D(*TP*TP*TP*TP*TP*T)-3'), DNA (5'-D(P*TP*CP*CP*GP*AP*GP*CP*GP*AP*A)-3'), DNA (5'-D(P*TP*TP*TP*GP*CP*CP*CP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.1 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR1
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BU of 8dr1 by Molmil
Consensus closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2)
分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.14 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR3
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BU of 8dr3 by Molmil
Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) with NTD
分子名称: DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*A)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.2 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
5L6H
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BU of 5l6h by Molmil
Uba1 in complex with Ub-ABPA3 covalent adduct
分子名称: ACETATE ION, CHLORIDE ION, GLYCEROL, ...
著者Misra, M, Schindelin, H.
登録日2016-05-30
公開日2017-06-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.
Structure, 25, 2017
1PLQ
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BU of 1plq by Molmil
CRYSTAL STRUCTURE OF THE EUKARYOTIC DNA POLYMERASE PROCESSIVITY FACTOR PCNA
分子名称: MERCURY (II) ION, PROLIFERATING CELL NUCLEAR ANTIGEN (PCNA)
著者Krishna, T.S.R, Kong, X.-P, Gary, S, Burgers, P.M, Kuriyan, J.
登録日1995-01-02
公開日1995-03-31
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Crystal structure of the eukaryotic DNA polymerase processivity factor PCNA.
Cell(Cambridge,Mass.), 79, 1994
8DR6
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Closed state of RFC:PCNA bound to a nicked dsDNA
分子名称: ADENOSINE-5'-DIPHOSPHATE, DNA (32-MER), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.39 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
7ZW0
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BU of 7zw0 by Molmil
FAP-80S Complex - Rotated state
分子名称: 18S ribosomal RNA (RDN18-1), 25S ribosomal RNA (RDN25-1), 40S ribosomal protein S0-A, ...
著者Ikeuchi, K, Buschauer, R, Berninghausen, O, Becker, T, Beckmann, R.
登録日2022-05-17
公開日2022-10-05
実験手法ELECTRON MICROSCOPY (2.4 Å)
主引用文献Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover.
Mol.Cell, 82, 2022
8DR0
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BU of 8dr0 by Molmil
Closed state of RFC:PCNA bound to a 3' ss/dsDNA junction
分子名称: DNA (5'-D(P*CP*CP*CP*CP*GP*GP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), DNA (5'-D(P*TP*TP*TP*TP*TP*TP*CP*GP*GP*GP*GP*GP*GP*GP*CP*CP*CP*CP*GP*GP*GP*G)-3'), GUANOSINE-5'-DIPHOSPHATE, ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-24
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.42 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8DR4
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BU of 8dr4 by Molmil
Open state of RFC:PCNA bound to a 3' ss/dsDNA junction (DNA2) without NTD
分子名称: DNA (5'-D(P*AP*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*CP*CP*CP*CP*TP*TP*T)-3'), DNA (5'-D(P*CP*CP*CP*CP*CP*CP*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.45 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
3GPN
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BU of 3gpn by Molmil
Structure of the non-trimeric form of the E113G PCNA mutant protein
分子名称: Proliferating cell nuclear antigen
著者Freudenthal, B.D, Gakhar, L, Ramaswamy, S, Washington, M.T.
登録日2009-03-23
公開日2009-06-16
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献A charged residue at the subunit interface of PCNA promotes trimer formation by destabilizing alternate subunit interactions.
Acta Crystallogr.,Sect.D, 65, 2009
7ZUX
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BU of 7zux by Molmil
Collided ribosome in a disome unit from S. cerevisiae
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
登録日2022-05-13
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (2.5 Å)
主引用文献Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
5U4P
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BU of 5u4p by Molmil
Protein-protein complex between 26S proteasome regulatory subunit RPN8, RPN11, and Ubiquitin S31
分子名称: 26S proteasome regulatory subunit RPN11, 26S proteasome regulatory subunit RPN8, Ubiquitin-40S ribosomal protein S31, ...
著者Worden, E.J, Dong, K.C, Martin, A.
登録日2016-12-05
公開日2017-09-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome.
Mol. Cell, 67, 2017
6T4Q
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BU of 6t4q by Molmil
Structure of yeast 80S ribosome stalled on the CGA-CCG inhibitory codon combination.
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R.
登録日2019-10-14
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (2.6 Å)
主引用文献Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
3V60
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BU of 3v60 by Molmil
Structure of S. cerevisiae PCNA conjugated to SUMO on lysine 164
分子名称: Proliferating cell nuclear antigen, SULFATE ION, Ubiquitin-like protein SMT3
著者Armstrong, A.A, Mohideen, F, Lima, C.D.
登録日2011-12-18
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Recognition of SUMO-modified PCNA requires tandem receptor motifs in Srs2.
Nature, 483, 2012
6W9W
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BU of 6w9w by Molmil
R80A PCNA mutant defective in BIR
分子名称: Proliferating cell nuclear antigen
著者Ripley, B.M, Washington, M.T.
登録日2020-03-23
公開日2020-09-23
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (2.65 Å)
主引用文献Structural analysis of PCNA mutant proteins defective in BIR, FF248-249AA and R80A
To be Published
5L6J
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BU of 5l6j by Molmil
Uba1 in complex with Ub-MLN7243 covalent adduct
分子名称: CHLORIDE ION, GLYCEROL, SULFATE ION, ...
著者Misra, M, Schindelin, H.
登録日2016-05-30
公開日2017-06-14
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Dissecting the Specificity of Adenosyl Sulfamate Inhibitors Targeting the Ubiquitin-Activating Enzyme.
Structure, 25, 2017
4L6P
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BU of 4l6p by Molmil
Structure of C22Y Mutant PCNA protein defective in DNA mismatch repair
分子名称: GLYCEROL, Proliferating cell nuclear antigen
著者Washington, T, Boehm, E.
登録日2013-06-12
公開日2014-10-01
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.68 Å)
主引用文献Distinct structural alterations in proliferating cell nuclear antigen block DNA mismatch repair.
Biochemistry, 52, 2013
7MPJ
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BU of 7mpj by Molmil
Stm1 bound vacant 80S structure isolated from wild-type
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Rai, J, Zhao, Y, Li, H.
登録日2021-05-04
公開日2022-05-11
最終更新日2023-12-13
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献CryoEM structures of pseudouridine-free ribosome suggest impacts of chemical modifications on ribosome conformations.
Structure, 30, 2022
3CMM
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BU of 3cmm by Molmil
Crystal Structure of the Uba1-Ubiquitin Complex
分子名称: PROLINE, Ubiquitin, Ubiquitin-activating enzyme E1 1
著者Lee, I, Schindelin, H.
登録日2008-03-23
公開日2008-08-05
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Structural insights into E1-catalyzed ubiquitin activation and transfer to conjugating enzymes.
Cell(Cambridge,Mass.), 134, 2008
8DR7
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BU of 8dr7 by Molmil
Open state of RFC:PCNA bound to a nicked dsDNA
分子名称: DNA (26-MER), DNA (5'-D(P*AP*GP*GP*GP*GP*GP*GP*GP*GP*GP*G)-3'), DNA (5'-D(P*GP*GP*CP*CP*CP*CP*CP*CP*CP*GP*GP*C)-3'), ...
著者Schrecker, M, Hite, R.K.
登録日2022-07-20
公開日2022-08-17
最終更新日2024-02-14
実験手法ELECTRON MICROSCOPY (2.7 Å)
主引用文献Multistep loading of a DNA sliding clamp onto DNA by replication factor C.
Elife, 11, 2022
8CDL
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BU of 8cdl by Molmil
80S S. cerevisiae ribosome with ligands in hybrid-2 pre-translocation (PRE-H2) complex
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Milicevic, N, Jenner, L, Myasnikov, A, Yusupov, M, Yusupova, G.
登録日2023-01-31
公開日2023-09-20
最終更新日2024-04-24
実験手法ELECTRON MICROSCOPY (2.72 Å)
主引用文献mRNA reading frame maintenance during eukaryotic ribosome translocation.
Nature, 625, 2024

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