3LN4
| Crystal structure of HLA-B*4103 in complex with a 16mer self-peptide derived from heterogeneous nuclear ribonucleoproteins C1/C2 | 分子名称: | 16-mer peptide from Heterogeneous nuclear ribonucleoproteins C1/C2, ACETATE ION, Beta-2-microglobulin, ... | 著者 | Theodossis, A, Gras, S, Rossjohn, J. | 登録日 | 2010-02-01 | 公開日 | 2010-10-20 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.296 Å) | 主引用文献 | The impact of human leukocyte antigen (HLA) micropolymorphism on ligand specificity within the HLA-B*41 allotypic family Haematologica, 96, 2011
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3BWA
| Crystal Structure of HLA B*3508 in complex with a HCMV 8-mer peptide from the pp65 protein | 分子名称: | Beta-2-microglobulin, FPT peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ... | 著者 | Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R. | 登録日 | 2008-01-08 | 公開日 | 2008-04-22 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection Blood, 111, 2008
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3SPV
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6V2P
| HLA-B*57:03 presenting the peptide ASLNLPAVSW | 分子名称: | ACETATE ION, Beta-2-microglobulin, DI(HYDROXYETHYL)ETHER, ... | 著者 | Maclachlan, B, Rossjohn, J, Vivian, J.P. | 登録日 | 2019-11-25 | 公開日 | 2020-05-20 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function. Proc.Natl.Acad.Sci.USA, 117, 2020
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3D25
| Crystal structure of HA-1 minor histocompatibility antigen bound to human class I MHC HLA-A2 | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, A-2 alpha chain, ... | 著者 | Nicholls, S, Piper, K.P, Mohammed, F, Dafforn, T.R, Tenzer, S, Salim, M, Mahendra, P, Craddock, C, van Endert, P, Schild, H, Cobbold, M, Engelhard, V.H, Moss, P.A.H, Willcox, B.E. | 登録日 | 2008-05-07 | 公開日 | 2009-02-10 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Secondary anchor polymorphism in the HA-1 minor histocompatibility antigen critically affects MHC stability and TCR recognition Proc.Natl.Acad.Sci.USA, 106, 2009
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3MRG
| Crystal Structure of MHC class I HLA-A2 molecule complexed with HCV NS3-1073-1081 nonapeptide | 分子名称: | 9-meric peptide from Serine protease/NTPase/helicase NS3, Beta-2-microglobulin, CITRIC ACID, ... | 著者 | Gras, S, Reiser, J.-B, Echasserieau, K, Saulquin, X, Bonneville, M, Housset, D. | 登録日 | 2010-04-29 | 公開日 | 2011-05-25 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Analysis of Relationships between Peptide/MHC Structural Features and Naive T Cell Frequency in Humans. J.Immunol., 193, 2014
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7WZZ
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6MT6
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7KGQ
| Crystal Structure of HLA-A*0201in complex with SARS-CoV-2 N222-230 | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, CADMIUM ION, ... | 著者 | Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S. | 登録日 | 2020-10-18 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.34 Å) | 主引用文献 | The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule. Iscience, 24, 2021
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6TRN
| Crystal structure of HLA A2*01-AVYDGREHTV | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, MAGE-A4 peptide (amino acids 230-239) variant, ... | 著者 | Coles, C.H, McMurran, C, Lloyd, A, Hibbert, L, Lupardus, P.J, Cole, D.K, Harper, S. | 登録日 | 2019-12-19 | 公開日 | 2020-06-24 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | T cell receptor interactions with human leukocyte antigen govern indirect peptide selectivity for the cancer testis antigen MAGE-A4. J.Biol.Chem., 295, 2020
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2BVP
| Structures of Three HIV-1 HLA-B5703-Peptide Complexes and Identification of Related HLAs Potentially Associated with Long-Term Non-Progression | 分子名称: | BETA-2-MICROGLOBULIN, HIV-P24, HLA CLASS I HISTOCOMPATIBILITY ANTIGEN, ... | 著者 | Stewart-Jones, G.B, Gillespie, G, Overton, I.M, Kaul, R, Roche, P, Mcmichael, A.J, Rowland-Jones, S, Jones, E.Y. | 登録日 | 2005-07-01 | 公開日 | 2005-09-07 | 最終更新日 | 2019-10-09 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression. J Immunol., 175, 2005
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6MTL
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6JOZ
| Crystal structure of BRLF peptide from EBV in complex with HLA-A1101. | 分子名称: | ALA-THR-ILE-GLY-THR-ALA-MET-TYR-LYS, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Huan, X, Xiao, Z, Tadwal, V.S, Ren, E.C. | 登録日 | 2019-03-25 | 公開日 | 2020-01-29 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.35 Å) | 主引用文献 | Crystal structure of suboptimal viral fragments of Epstein Barr Virus Rta peptide-HLA complex that stimulate CD8 T cell response. Sci Rep, 9, 2019
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5C0G
| HLA-A02 carrying YLGGPDFPTI | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2015-06-12 | 公開日 | 2016-05-04 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J.Clin.Invest., 126, 2016
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6Y2B
| Crystal structure of HLA-B2709 complexed with the nona-peptide mQ | 分子名称: | Beta-2-microglobulin, GLYCEROL, Lymphocyte antigen HLA-B27, ... | 著者 | Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A. | 登録日 | 2020-02-15 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.37 Å) | 主引用文献 | A CENTRAL PEPTIDE RESIDUE CAN CONTROL
MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION to be published
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8E13
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5WL1
| Crystal Structure of Human CD1b in Complex with PG | 分子名称: | (19S,22R,25R)-22,25,26-trihydroxy-16,22-dioxo-17,21,23-trioxa-22lambda~5~-phosphahexacosan-19-yl (9E)-octadec-9-enoate, 1,2-ETHANEDIOL, Beta-2-microglobulin, ... | 著者 | Shahine, A, Gras, S, Rossjohn, J. | 登録日 | 2017-07-25 | 公開日 | 2017-11-01 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | A molecular basis of human T cell receptor autoreactivity toward self-phospholipids. Sci Immunol, 2, 2017
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6Y27
| Crystal structure of HLA-B2709 complexed with the nona-peptide mA | 分子名称: | Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ... | 著者 | Loll, B, Rueckert, C, Ziegler, B.-U, Ziegler, A. | 登録日 | 2020-02-15 | 公開日 | 2020-12-23 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | A CENTRAL PEPTIDE RESIDUE CAN CONTROL
MHC POLYMORPHISM-DEPENDENT ANTIGEN PRESENTATION to be published
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6PYW
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4U1J
| HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ... | 著者 | Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K. | 登録日 | 2014-07-15 | 公開日 | 2015-04-08 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.38 Å) | 主引用文献 | A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape. Retrovirology, 12, 2015
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5N1Y
| HLA-A02 carrying MVWGPDPLYV | 分子名称: | 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ... | 著者 | Rizkallah, P.J, Bulek, A.M, Cole, D.K, Sewell, A.K. | 登録日 | 2017-02-06 | 公開日 | 2017-02-15 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.39 Å) | 主引用文献 | Hotspot autoimmune T cell receptor binding underlies pathogen and insulin peptide cross-reactivity. J. Clin. Invest., 126, 2016
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6P2C
| Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation | 分子名称: | Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ... | 著者 | Li, L, Batliwala, M, Bouvier, M. | 登録日 | 2019-05-21 | 公開日 | 2019-10-16 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.396 Å) | 主引用文献 | ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation. J.Biol.Chem., 294, 2019
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7KGP
| Crystal Structure of HLA-A*0201 in complex with SARS-CoV-2 N316-324 | 分子名称: | ACETATE ION, Beta-2-microglobulin, CADMIUM ION, ... | 著者 | Szeto, C, Chatzileontiadou, D.S.M, Riboldi-Tunnicliffe, A, Gras, S. | 登録日 | 2020-10-18 | 公開日 | 2021-01-20 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.396 Å) | 主引用文献 | The presentation of SARS-CoV-2 peptides by the common HLA-A * 02:01 molecule. Iscience, 24, 2021
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7X1B
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6TDP
| Crystal structure of the disulfide engineered HLA-A0201 molecule in complex with one GL dipeptide in the A pocket. | 分子名称: | Beta-2-microglobulin, GLYCEROL, GLYCINE, ... | 著者 | Anjanappa, R, Garcia Alai, M, Springer, S, Meijers, R. | 登録日 | 2019-11-10 | 公開日 | 2020-03-25 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structures of peptide-free and partially loaded MHC class I molecules reveal mechanisms of peptide selection. Nat Commun, 11, 2020
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