7RDE
 
 | | Human Triose Phosphate Isomerase Q181P | | 分子名称: | BROMIDE ION, CALCIUM ION, Triosephosphate isomerase | | 著者 | VanDemark, A.P, Kowalski, J. | | 登録日 | 2021-07-09 | | 公開日 | 2022-05-04 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.31 Å) | | 主引用文献 | Itavastatin and resveratrol increase triosephosphate isomerase protein in a newly identified variant of TPI deficiency.
Dis Model Mech, 15, 2022
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4UNL
 | | Crystal structure of a single mutant (N71D) of triosephosphate isomerase from human | | 分子名称: | TRIOSEPHOSPHATE ISOMERASE | | 著者 | DeLaMora-DeLaMora, I, Torres-Larios, A, Enriquez-Flores, S, Mendez, S.T, Castillo-Villanueva, A, Gomez-Manzo, S, Lopez-Velazquez, G, Marcial-Quino, J, Torres-Arroyo, A, Garcia-Torres, I, Reyes-Vivas, H, Oria-Hernandez, J. | | 登録日 | 2014-05-29 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | | 主引用文献 | Crystal Structure of a Single Mutant (N71D) of Triosephosphate Isomerase from Human
To be Published
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4POC
 | | Structure of Triosephosphate Isomerase Wild Type human enzyme. | | 分子名称: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | 登録日 | 2014-02-25 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.601 Å) | | 主引用文献 | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
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6UPF
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4ZVJ
 | | Structure of human triose phosphate isomerase K13M | | 分子名称: | POTASSIUM ION, SODIUM ION, Triosephosphate isomerase | | 著者 | Amrich, C.G, Smith, C, Heroux, A, VanDemark, A.P. | | 登録日 | 2015-05-18 | | 公開日 | 2016-03-09 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.6996 Å) | | 主引用文献 | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim. Biophys. Acta, 1852, 2015
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2JK2
 | | STRUCTURAL BASIS OF HUMAN TRIOSEPHOSPHATE ISOMERASE DEFICIENCY. CRYSTAL STRUCTURE OF THE WILD TYPE ENZYME. | | 分子名称: | TRIOSEPHOSPHATE ISOMERASE | | 著者 | Rodriguez-Almazan, C, Arreola-Alemon, R, Rodriguez-Larrea, D, Aguirre-Lopez, B, De Gomez-Puyou, M.T, Perez-Montfort, R, Costas, M, Gomez-Puyou, A, Torres-Larios, A. | | 登録日 | 2008-06-22 | | 公開日 | 2008-07-01 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural Basis of Human Triosephosphate Isomerase Deficiency: Mutation E104D is Related to Alterations of a Conserved Water Network at the Dimer Interface.
J.Biol.Chem., 283, 2008
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6UP1
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2VOM
 | | Structural basis of human triosephosphate isomerase deficiency. Mutation E104D and correlation to solvent perturbation. | | 分子名称: | TRIOSEPHOSPHATE ISOMERASE | | 著者 | Rodriguez-Almazan, C, Arreola-Alemon, R, Rodriguez-Larrea, D, Aguirre-Lopez, B, de Gomez-Puyou, M.T, Perez-Montfort, R, Costas, M, Gomez-Puyou, A, Torres-Larios, A. | | 登録日 | 2008-02-19 | | 公開日 | 2008-06-17 | | 最終更新日 | 2023-12-13 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural Basis of Human Triosephosphate Isomerase Deficiency: Mutation E104D is Related to Alterations of a Conserved Water Network at the Dimer Interface.
J.Biol.Chem., 283, 2008
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4BR1
 | | Protease-induced heterodimer of human triosephosphate isomerase. | | 分子名称: | TRIOSEPHOSPHATE ISOMERASE | | 著者 | DeLaMora-DeLaMora, I, Torres-Larios, A, Hernandez-Alcantara, G, Mendoza-Hernandez, G, Enriquez-Flores, S, Mendez, S.T, Castillo-Villanueva, A, Garcia-Torres, I, Torres-Arroyo, A, Gomez-Manzo, S, Marcial-Quino, J, Oria-Hernandez, J, Lopez-Velazquez, G, Reyes-Vivas, H. | | 登録日 | 2013-06-03 | | 公開日 | 2013-06-12 | | 最終更新日 | 2023-12-20 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Differential Proteolysis in Human Triosephosphate Isomerase
To be Published
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6UP5
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1KLU
 | | Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | | 分子名称: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | 著者 | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | | 登録日 | 2001-12-12 | | 公開日 | 2002-08-02 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | | 主引用文献 | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
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4POD
 | | Structure of Triosephosphate Isomerase I170V mutant human enzyme. | | 分子名称: | BROMIDE ION, PHOSPHATE ION, POTASSIUM ION, ... | | 著者 | Amrich, C.G, Aslam, A.A, Heroux, A, VanDemark, A.P. | | 登録日 | 2014-02-25 | | 公開日 | 2015-01-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.99 Å) | | 主引用文献 | Triosephosphate isomerase I170V alters catalytic site, enhances stability and induces pathology in a Drosophila model of TPI deficiency.
Biochim.Biophys.Acta, 1852, 2015
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4UNK
 | | Crystal structure of human triosephosphate isomerase (mutant N15D) | | 分子名称: | TRIOSEPHOSPHATE ISOMERASE | | 著者 | DeLaMora-DeLaMora, I, Torres-Larios, A, Enriquez-Flores, S, Mendez, S.T, Castillo-Villanueva, A, Gomez-Manzo, S, Lopez-Velazquez, G, Marcial-Quino, J, Torres-Arroyo, A, Garcia-Torres, I, Reyes-Vivas, H, Oria-Hernandez, J. | | 登録日 | 2014-05-29 | | 公開日 | 2015-02-04 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Crystal Structure of Human Triosephosphate Isomerase (Mutant N15D)
To be Published
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6UP8
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7T0Q
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7UXB
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6D43
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7UXV
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6NLH
 | | Structure of human triose phosphate isomerase R189A | | 分子名称: | BROMIDE ION, PHOSPHATE ION, SODIUM ION, ... | | 著者 | Richards, K.R, Roland, B.P, Palladino, M.J, VanDemark, A.P. | | 登録日 | 2019-01-08 | | 公開日 | 2019-06-19 | | 最終更新日 | 2023-10-11 | | 実験手法 | X-RAY DIFFRACTION (2.199 Å) | | 主引用文献 | Missense variant in TPI1 (Arg189Gln) causes neurologic deficits through structural changes in the triosephosphate isomerase catalytic site and reduced enzyme levels in vivo.
Biochim Biophys Acta Mol Basis Dis, 1865, 2019
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1WYI
 | | human triosephosphate isomerase of new crystal form | | 分子名称: | Triosephosphate isomerase | | 著者 | Kinoshita, T. | | 登録日 | 2005-02-14 | | 公開日 | 2005-04-12 | | 最終更新日 | 2024-03-13 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure of a high-resolution crystal form of human triosephosphate isomerase: improvement of crystals using the gel-tube method.
Acta Crystallogr.,Sect.F, 61, 2005
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7SX1
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6C2G
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1KLG
 | | Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2) | | 分子名称: | ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ... | | 著者 | Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A. | | 登録日 | 2001-12-11 | | 公開日 | 2002-08-02 | | 最終更新日 | 2021-10-27 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
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4E41
 | | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4 | | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-1 beta chain, ... | | 著者 | Deng, L, Langley, R.J, Wang, Q, Topalian, S.L, Mariuzza, R.A. | | 登録日 | 2012-03-11 | | 公開日 | 2012-08-29 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor G4
Proc.Natl.Acad.Sci.USA, 2012
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2IAN
 | | Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | | 分子名称: | 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ... | | 著者 | Deng, L, Langley, R.J, Mariuzza, R.A. | | 登録日 | 2006-09-08 | | 公開日 | 2007-04-03 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
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