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PDB: 64 件

6LN2
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Crystal structure of full length human GLP1 receptor in complex with Fab fragment (Fab7F38)
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Fab7F38_heavy chain, Fab7F38_light chain, ...
著者Wu, F, Yang, L, Hang, K, Laursen, M, Wu, L, Han, G.W, Ren, Q, Roed, N.K, Lin, G, Hanson, M, Jiang, H, Wang, M, Reedtz-Runge, S, Song, G, Stevens, R.C.
登録日2019-12-28
公開日2020-03-18
最終更新日2023-11-22
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Full-length human GLP-1 receptor structure without orthosteric ligands.
Nat Commun, 11, 2020
8AS2
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Structure of arrestin2 in complex with 4P CCR5 phosphopeptide and Fab30
分子名称: Beta-arrestin-1, C-C chemokine receptor type 5, Fab30 heavy chain, ...
著者Isaikina, P, Jakob, R.P, Maier, T, Grzesiek, S.
登録日2022-08-18
公開日2023-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes.
Mol.Cell, 83, 2023
7NW3
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X-ray crystallographic study of PIYDIN, which contains the truncation determinants of binding PI and N, bound to RoAb13, a CCR5 antibody
分子名称: Antibody RoAb13 Heavy Chain, Antibody RoAb13 Light Chain, Region from C-C chemokine receptor type 5 N-terminal domain
著者Saridakis, E, Helliwell, J.R, Govada, L, Chayen, N.E.
登録日2021-03-16
公開日2021-07-21
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.200011 Å)
主引用文献X-ray crystallographic studies of RoAb13 bound to PIYDIN, a part of the N-terminal domain of C-C chemokine receptor 5.
Iucrj, 8, 2021
6ME9
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XFEL crystal structure of human melatonin receptor MT2 in complex with ramelteon
分子名称: N-{2-[(8S)-1,6,7,8-tetrahydro-2H-indeno[5,4-b]furan-8-yl]ethyl}propanamide, Soluble cytochrome b562,Melatonin receptor type 1B,Rubredoxin, ZINC ION
著者Johansson, L.C, Stauch, B, McCorvy, J, Han, G.W, Patel, N, Batyuk, A, Gati, C, Li, C, Grandner, J, Hao, S, Olsen, R.H.J, Tribo, A.R, Zaare, S, Zhu, L, Zatsepin, N.A, Weierstall, U, Liu, W, Roth, B.L, Katritch, V, Cherezov, V.
登録日2018-09-05
公開日2019-04-24
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献XFEL structures of the human MT2melatonin receptor reveal the basis of subtype selectivity.
Nature, 569, 2019
6GPS
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CRYSTAL STRUCTURE OF CCR2A IN COMPLEX WITH MK-0812
分子名称: C-C chemokine receptor type 2,Rubredoxin,C-C chemokine receptor type 2, ZINC ION, [(3~{S},4~{S})-3-methoxyoxan-4-yl]-[(1~{R},3~{S})-3-propan-2-yl-3-[[3-(trifluoromethyl)-7,8-dihydro-5~{H}-1,6-naphthyridin-6-yl]carbonyl]cyclopentyl]azanium
著者Pautsch, A, Schnapp, G.
登録日2018-06-07
公開日2019-01-02
最終更新日2019-03-13
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Crystal Structure of CC Chemokine Receptor 2A in Complex with an Orthosteric Antagonist Provides Insights for the Design of Selective Antagonists.
Structure, 27, 2019
8AS3
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Structure of arrestin2 in complex with 6P CCR5 phosphopeptide and Fab30
分子名称: Beta-arrestin-1, C-C chemokine receptor type 5, Fab30 heavy chain, ...
著者Isaikina, P, Jakob, R.P, Maier, T, Grzesiek, S.
登録日2022-08-18
公開日2023-06-07
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献A key GPCR phosphorylation motif discovered in arrestin2⋅CCR5 phosphopeptide complexes.
Mol.Cell, 83, 2023
6MEO
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Structural basis of coreceptor recognition by HIV-1 envelope spike
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shaik, M.M, Chen, B.
登録日2018-09-06
公開日2018-12-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis of coreceptor recognition by HIV-1 envelope spike.
Nature, 565, 2018
6MET
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Structural basis of coreceptor recognition by HIV-1 envelope spike
分子名称: 2-acetamido-2-deoxy-alpha-D-galactopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ...
著者Shaik, M.M, Chen, B.
登録日2018-09-07
公開日2018-12-12
最終更新日2020-07-29
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Structural basis of coreceptor recognition by HIV-1 envelope spike.
Nature, 565, 2018
2RLL
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CCR5 Nt(7-15)
分子名称: 9-mer from C-C chemokine receptor type 5
著者Bewley, C.A, Lam, S.N.
登録日2007-07-21
公開日2007-09-25
最終更新日2023-11-15
実験手法SOLUTION NMR
主引用文献Structures of the CCR5 N terminus and of a tyrosine-sulfated antibody with HIV-1 gp120 and CD4
Science, 317, 2007
1BFY
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SOLUTION STRUCTURE OF REDUCED CLOSTRIDIUM PASTEURIANUM RUBREDOXIN, NMR, 20 STRUCTURES
分子名称: FE (III) ION, RUBREDOXIN
著者Bertini, I, Kurtz Junior, D.M, Eidsness, M.K, Liu, G, Luchinat, C, Rosato, A, Scott, R.A.
登録日1998-05-23
公開日1999-05-25
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of Reduced Clostridium Pasteurianum Rubredoxin
J.Biol.Inorg.Chem., 3, 1998
2RRS
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NMR Structure of LC4 transmembrane segment of CCR5
分子名称: C-C chemokine receptor type 5
著者Miyamoto, K.
登録日2011-04-11
公開日2012-04-11
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution Structure of LC4 Transmembrane Segment of CCR5
Plos One, 6, 2011
6FGP
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NMR solution structure of monomeric CCL5 in complex with a doubly-sulfated N-terminal segment of CCR5
分子名称: C-C chemokine receptor type 5, C-C motif chemokine 5
著者Anglister, J, Abayev, M.
登録日2018-01-11
公開日2018-04-18
最終更新日2022-03-30
実験手法SOLUTION NMR
主引用文献The solution structure of monomeric CCL5 in complex with a doubly sulfated N-terminal segment of CCR5.
FEBS J., 285, 2018
2L87
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The 27-residue N-terminus CCR5-peptide in a ternary complex with HIV-1 gp120 and a CD4-mimic peptide
分子名称: C-C chemokine receptor type 5
著者Schnur, E, Noah, E, Ayzenshtat, I, Sargsyan, H, Inui, T, Ding, F.X, Arshava, B, Sagi, Y, Kessler, N, Levy, R, Scherf, T, Naider, F, Anglister, J.
登録日2011-01-06
公開日2011-07-27
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献The Conformation and Orientation of a 27-Residue CCR5 Peptide in a Ternary Complex with HIV-1 gp120 and a CD4-Mimic Peptide.
J.Mol.Biol., 410, 2011
2MZX
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CCR5-ECL2 helical structure, residues Q186-T195
分子名称: C-C chemokine receptor type 5
著者Abayev, M, Anglister, J.
登録日2015-02-26
公開日2015-04-22
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献An extended CCR5 ECL2 peptide forms a helix that binds HIV-1 gp120 through non-specific hydrophobic interactions.
Febs J., 282, 2015
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