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PDB: 21 件
3K8T
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BU of 3k8t by Molmil
Structure of eukaryotic rnr large subunit R1 complexed with designed adp analog compound
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, 2'-deoxy-2'-(2-hydroxyethyl)adenosine 5'-(trihydrogen diphosphate), GLYCEROL, ...
著者Sun, D, Xu, H, Dealwis, C, Lee, R.E.
登録日2009-10-14
公開日2010-03-02
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Design, Synthesis, and Evaluation of 2'-(2-Hydroxyethyl)-2'-deoxyadenosine and the 5'-Diphosphate Derivative as Ribonucleotide Reductase Inhibitors
Chemmedchem, 4, 2009
2CVX
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BU of 2cvx by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-14
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
3S87
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BU of 3s87 by Molmil
Structure of Yeast Ribonucleotide Reductase 1 with dGTP and ADP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D.
登録日2011-05-27
公開日2012-04-11
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
3RSR
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BU of 3rsr by Molmil
Crystal Structure of 5-NITP Inhibition of Yeast Ribonucleotide Reductase
分子名称: 1-{2-DEOXY-5-O-[(R)-HYDROXY{[(R)-HYDROXY(PHOSPHONOOXY)PHOSPHORYL]OXY}PHOSPHORYL]-BETA-D-ERYTHRO-PENTOFURANOSYL}-5-NITRO-1H-INDOLE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1
著者Wan, Q, Mohammed, F, Jha, S, Motea, E, Berdis, A, Dealwis, C.G.
登録日2011-05-02
公開日2012-11-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Evaluating the therapeutic potential of a non-natural nucleotide that inhibits human ribonucleotide reductase.
Mol.Cancer Ther., 11, 2012
2EUD
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BU of 2eud by Molmil
Structures of Yeast Ribonucleotide Reductase I complexed with Ligands and Subunit Peptides
分子名称: GEMCITABINE DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Dealwis, C, Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J.
登録日2005-10-28
公開日2006-03-07
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I define gemcitabine diphosphate binding and subunit assembly.
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVY
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BU of 2cvy by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: 9-per peptide from Ribonucleoside-diphosphate reductase small chain 1, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ...
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-14
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVW
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BU of 2cvw by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1, ...
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-14
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2ZLG
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BU of 2zlg by Molmil
The Structual Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase
分子名称: (5R,9S,12S,15S,18S,21S)-21-benzyl-12,18-bis(carboxymethyl)-15-cyclohexyl-1-(9H-fluoren-9-yl)-4-methyl-9-(2-methylpropyl)-3,6,10,13,16,19-hexaoxo-5-phenyl-2-oxa-4,8,11,14,17,20-hexaazadocosan-22-oic acid, GLYCEROL, Ribonucleoside-diphosphate reductase large chain 1
著者Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C.
登録日2008-04-09
公開日2008-08-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
3TB9
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BU of 3tb9 by Molmil
Structure of Yeast Ribonucleotide Reductase 1 Q288A with AMPPNP and CDP
分子名称: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D.
登録日2011-08-05
公開日2012-04-04
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (2.53 Å)
主引用文献Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase.
J.Mol.Biol., 419, 2012
2ZLF
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BU of 2zlf by Molmil
The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase
分子名称: FTLDADF, Ribonucleoside-diphosphate reductase large chain 1
著者Xu, H, Fairman, J.W, Wijerathna, S.R, LaMacchia, J, Kreischer, N.R, Helmbrecht, E, Cooperman, B.S, Dealwis, C.
登録日2008-04-09
公開日2008-08-19
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.59 Å)
主引用文献The Structural Basis for Peptidomimetic Inhibition of Eukaryotic Ribonucleotide Reductase: A Conformationally Flexible Pharmacophore
J.Med.Chem., 51, 2008
1ZZD
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BU of 1zzd by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: Ribonucleoside-diphosphate reductase large chain 1, Ribonucleoside-diphosphate reductase small chain 2
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-13
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVS
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BU of 2cvs by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: Ribonucleoside-diphosphate reductase large chain 1
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-14
公開日2006-03-07
最終更新日2024-10-16
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
3S8C
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BU of 3s8c by Molmil
Structure of Yeast Ribonucleotide Reductase 1 R293A with AMPPNP and CDP
分子名称: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D.
登録日2011-05-27
公開日2012-04-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.77 Å)
主引用文献Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
3TBA
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BU of 3tba by Molmil
Structure of Yeast Ribonucleotide Reductase 1 Q288A with dGTP and ADP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
著者Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.
登録日2011-08-05
公開日2012-04-04
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Role of Arginine 293 and Glutamine 288 in Communication between Catalytic and Allosteric Sites in Yeast Ribonucleotide Reductase.
J.Mol.Biol., 419, 2012
3S8B
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BU of 3s8b by Molmil
Structure of Yeast Ribonucleotide Reductase 1 with AMPPNP and CDP
分子名称: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D.
登録日2011-05-27
公開日2012-04-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
2CVV
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BU of 2cvv by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1, ...
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-14
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
1ZYZ
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BU of 1zyz by Molmil
Structures of Yeast Ribonucloetide Reductase I
分子名称: GLYCINE, Ribonucleoside-diphosphate reductase large chain 1
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-13
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
2CVU
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BU of 2cvu by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: CYTIDINE-5'-DIPHOSPHATE, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, ...
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-14
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
3S8A
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BU of 3s8a by Molmil
Structure of Yeast Ribonucleotide Reductase R293A with dGTP
分子名称: 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ribonucleoside-diphosphate reductase large chain 1
著者Ahmad, M.F, Kaushal, P.S, Wan, Q, Wijeratna, S.R, Huang, M, Dealwis, C.D.
登録日2011-05-27
公開日2012-04-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and biochemical basis of lethal mutant R293A of yeast ribonucleotide reductase
To be Published
2CVT
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BU of 2cvt by Molmil
Structures of Yeast Ribonucleotide Reductase I
分子名称: MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Ribonucleoside-diphosphate reductase large chain 1
著者Xu, H, Faber, C, Uchiki, T, Fairman, J.W, Racca, J, Dealwis, C.
登録日2005-06-14
公開日2006-03-07
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (3.2 Å)
主引用文献Structures of eukaryotic ribonucleotide reductase I provide insights into dNTP regulation
Proc.Natl.Acad.Sci.Usa, 103, 2006
3PAW
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BU of 3paw by Molmil
Low resolution X-ray crystal structure of Yeast Rnr1p with dATP bound in the A-site
分子名称: Ribonucleoside-diphosphate reductase large chain 1
著者Fairman, J.W, Wijerathna, S.R, Dealwis, C.G.
登録日2010-10-19
公開日2011-02-23
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (6.61 Å)
主引用文献Structural basis for allosteric regulation of human ribonucleotide reductase by nucleotide-induced oligomerization.
Nat.Struct.Mol.Biol., 18, 2011

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