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PDB: 228 件

5IEH
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Structure of HLA-B*40:02 in complex with the phosphorylated endogenous peptide REF(p)SKEPEL
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Alpizar, A, Marcilla, M, Santiago, C.
登録日2016-02-25
公開日2016-12-07
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of HLA-B*40:02 in complex with the phosphorilated endogenous peptide REFpSKEPEL
To Be Published
6AT5
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BU of 6at5 by Molmil
Crystal structure of HLA-B*07:02 in complex with an NY-ESO-1 peptide
分子名称: Beta-2-microglobulin, Cancer/testis antigen 1 peptide, HLA class I histocompatibility antigen, ...
著者Gully, B.S, Rossjohn, J.
登録日2017-08-27
公開日2018-02-28
最終更新日2018-04-04
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.
Nat Commun, 9, 2018
4JQV
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HLA-B*18:01 in complex with Epstein-Barr virus BZLF1-derived peptide (residues 173-180)
分子名称: ACETATE ION, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Theodossis, A, Welland, A, Gras, S, Rossjohn, J.
登録日2013-03-20
公開日2013-06-26
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献HLA Peptide Length Preferences Control CD8+ T Cell Responses.
J.Immunol., 191, 2013
2HJL
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BU of 2hjl by Molmil
Crystal Structure of HLA-B5703 and HIV-1 peptide
分子名称: Beta-2-microglobulin, Gag protein, HLA class I histocompatibility antigen B-57
著者Gillespie, G.M.A, Stewart-Jones, G, Rengasamy, J, Beattie, T, Bwayo, J.J, Plummer, F.A.
登録日2006-06-30
公開日2006-10-03
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Strong TCR Conservation and Altered T Cell Cross-Reactivity Characterize a B*57-Restricted Immune Response in HIV-1 Infection.
J.Immunol., 177, 2006
6PYL
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Crystal Structure of HLA-B*2703 in complex with KK10, an HIV peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27:03 alpha chain, ...
著者Gras, S.
登録日2019-07-30
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.52 Å)
主引用文献Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
6PZ5
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Crystal Structure of HLA-B*2703 in complex with LRN, a self-peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B*27:03 alpha chain, ...
著者Gras, S.
登録日2019-07-31
公開日2019-11-27
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.
J.Biol.Chem., 294, 2019
7S79
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STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH SYNTHETIC PHOSPHONO-MLL PEPTIDE ANALOG
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
登録日2021-09-15
公開日2022-11-02
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.53 Å)
主引用文献Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
6MT4
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BU of 6mt4 by Molmil
Crystal Structure of HLA-B*37:01 in complex with NP338-L7S influenza peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-37 alpha chain, ...
著者Gras, S.
登録日2018-10-19
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Broad CD8+T cell cross-recognition of distinct influenza A strains in humans.
Nat Commun, 9, 2018
1UXS
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CRYSTAL STRUCTURE OF HLA-B*2705 COMPLEXED WITH THE LATENT MEMBRANE PROTEIN 2 PEPTIDE (LMP2)OF EPSTEIN-BARR VIRUS
分子名称: BETA-2-MICROGLOBULIN, GENE TERMINAL PROTEIN (MEMBRANE PROTEIN LMP-2A/LMP-2B), GLYCEROL, ...
著者Hulsmeyer, M, Kozerski, C, Fiorillo, M.T, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, B.
登録日2004-03-01
公開日2004-11-09
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Allele-Dependent Similarity between Viral and Self-Peptide Presentation by Hla-B27 Subtypes
J.Biol.Chem., 280, 2005
6MT5
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BU of 6mt5 by Molmil
Crystal Structure of HLA-B*37:01 in complex with NP338-V6L influenza peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-37 alpha chain, ...
著者Gras, S.
登録日2018-10-19
公開日2019-02-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献Broad CD8+T cell cross-recognition of distinct influenza A strains in humans.
Nat Commun, 9, 2018
3VFV
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BU of 3vfv by Molmil
crystal structure of HLA B*3508 LPEP-P9Ala, peptide mutant P9-ala
分子名称: Beta-2-microglobulin, LPEP peptide from EBV, P9A, ...
著者Liu, Y.C, Rossjohn, J, Gras, S.
登録日2012-01-10
公開日2012-02-22
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.55 Å)
主引用文献The Energetic Basis Underpinning T-cell Receptor Recognition of a Super-bulged Peptide Bound to a Major Histocompatibility Complex Class I Molecule.
J.Biol.Chem., 287, 2012
7S7D
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BU of 7s7d by Molmil
STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH SYNTHETIC SULFO-MLL PEPTIDE ANALOG
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Patskovska, L, Patskovsky, Y, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
登録日2021-09-15
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.56 Å)
主引用文献Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
6BXQ
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BU of 6bxq by Molmil
Crystal Structure of HLA-B*57:01 with an HIV peptide RKV
分子名称: Beta-2-microglobulin, HIV peptide RKV, MHC class I antigen
著者Gras, S, Rossjohn, J.
登録日2017-12-18
公開日2018-02-28
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics.
Proteomics, 18, 2018
5WMR
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BU of 5wmr by Molmil
Crystal Structure of HLA-B8 in complex with QIK, a CMV peptide
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-31
公開日2018-06-06
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.58 Å)
主引用文献Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
4U1H
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BU of 4u1h by Molmil
HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GAG protein, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.59 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
6P27
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BU of 6p27 by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provides novel insights into antigen processing and presentation
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Li, L, Batliwala, M, Bouvier, M.
登録日2019-05-21
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.593 Å)
主引用文献ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
6P23
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BU of 6p23 by Molmil
Structure of a nested set of N-terminally extended MHC I-peptides provide novel insights into antigen processing presentation
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Li, L, Batliwala, M, Bouvier, M.
登録日2019-05-20
公開日2019-10-16
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.595 Å)
主引用文献ERAP1 enzyme-mediated trimming and structural analyses of MHC I-bound precursor peptides yield novel insights into antigen processing and presentation.
J.Biol.Chem., 294, 2019
4QRU
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BU of 4qru by Molmil
Crystal Structure of HLA B*0801 in complex with ELR_MYM, ELRRKMMYM
分子名称: 55 kDa immediate-early protein 1, ACETATE ION, Beta-2-microglobulin, ...
著者Gras, S, Twist, K.-A, Rossjohn, J.
登録日2014-07-02
公開日2015-02-04
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular imprint of exposure to naturally occurring genetic variants of human cytomegalovirus on the T cell repertoire.
Sci Rep, 4, 2014
1ZHK
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BU of 1zhk by Molmil
Crystal structure of HLA-B*3501 presenting 13-mer EBV antigen LPEPLPQGQLTAY
分子名称: Beta-2-microglobulin, EBV-peptide LPEPLPQGQLTAY, HLA class I histocompatibility antigen, ...
著者Tynan, F.E, Borg, N.A, Miles, J.J, Beddoe, T, El-Hassen, D, Silins, S.L, van Zuylen, W.J, Purcell, A.W, Kjer-Nielsen, L, McCluskey, J, Burrows, S.R, Rossjohn, J.
登録日2005-04-26
公開日2005-05-17
最終更新日2014-04-16
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献The high resolution structures of highly bulged viral epitopes bound to the major histocompatability class I: Implications for T-cell receptor engagement and T-cell immunodominance
J.Biol.Chem., 280, 2005
1M6O
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BU of 1m6o by Molmil
Crystal Structure of HLA B*4402 in complex with HLA DPA*0201 peptide
分子名称: Beta-2-microglobulin, HLA DPA*0201 peptide, HLA class I histocompatibility antigen, ...
著者Macdonald, W.A, Purcell, A.W, Williams, D.S, Mifsud, N.A, Ely, L.K, Gorman, J.J, Clements, C.S, Kjer-Nielsen, L, Koelle, D.M, Brooks, A.G, Lovrecz, G.O, Lu, L, Rossjohn, J, McCluskey, J.
登録日2002-07-17
公開日2003-09-02
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A naturally selected dimorphism within the HLA-B44 supertype alters class I structure, peptide repertoire, and T cell recognition.
J.Exp.Med., 198, 2003
5WMP
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BU of 5wmp by Molmil
Crystal Structure of HLA-B7 in complex with TPR, a CMV peptide
分子名称: Beta-2-microglobulin, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ...
著者Gras, S, Rossjohn, J.
登録日2017-07-30
公開日2018-06-06
最終更新日2018-06-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.
J. Immunol., 200, 2018
5DEF
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BU of 5def by Molmil
Crystal structure of B*27:04 complex bound to the pVIPR peptide
分子名称: Beta-2-microglobulin, CHLORIDE ION, GLYCEROL, ...
著者Loll, B, Fabian, H, Huser, H, Hee, C.S, Uchanska-Ziegler, B, Ziegler, A.
登録日2015-08-25
公開日2015-11-18
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Increased Conformational Flexibility of HLA-B*27 Subtypes Associated With Ankylosing Spondylitis.
Arthritis Rheumatol, 68, 2016
4G9D
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Crystal Structure of HLA B2705-KK10
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Gras, S, Wilmann, P.G, Rossjohn, J.
登録日2012-07-23
公開日2013-03-20
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献A Molecular Basis for the Control of Preimmune Escape Variants by HIV-Specific CD8(+) T Cells.
Immunity, 38, 2013
7S8E
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STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE AND BOUND GLYCEROL
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Patskovsky, Y, Nyovanie, S, Patskovska, L, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
登録日2021-09-17
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
3VRI
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HLA-B*57:01-RVAQLENVYI in complex with abacavir
分子名称: 10-mer peptide, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Vivian, J.P, Illing, P.T, McCluskey, J, Rossjohn, J.
登録日2012-04-11
公開日2012-05-30
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.6 Å)
主引用文献Immune self-reactivity triggered by drug-modified HLA-peptide repertoire
Nature, 486, 2012

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