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PDB: 228 件

6BJ8
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TCR55 in complex with Pep20/HLA-B35
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Jude, K.M, Sibener, L.V, Yang, X, Garcia, K.C.
登録日2017-11-05
公開日2018-07-25
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding.
Cell, 174, 2018
3BW9
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Crystal Structure of HLA B*3508 in complex with a HCMV 12-mer peptide from the pp65 protein
分子名称: Beta-2-microglobulin, CPS peptide from 65 kDa lower matrix phosphoprotein, HLA class I histocompatibility antigen, ...
著者Wynn, K.K, Marland, Z, Cooper, L, Silins, S.L, Gras, S, Archbold, J.K, Tynan, F.E, Miles, J.J, McCluskey, J, Burrows, S.R, Rossjohn, J, Khanna, R.
登録日2008-01-08
公開日2008-04-22
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献Impact of clonal competition for peptide-MHC complexes on the CD8+ T-cell repertoire selection in a persistent viral infection
Blood, 111, 2008
4U1S
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HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-16
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
5T6Y
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HLA-B*57:01 presenting TSTFEDVKILAF
分子名称: ACETATE ION, Beta-2-microglobulin, Decapeptide: THR-SER-THR-PHE-GLU-ASP-VAL-LYS-ILE-LEU-ALA-PHE, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2016-09-02
公開日2017-03-01
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.76 Å)
主引用文献MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.
Nat. Struct. Mol. Biol., 24, 2017
4U1N
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HLA class I micropolymorphisms determine peptide-HLA landscape and dictate differential HIV-1 escape through identical epitopes
分子名称: 1,2-ETHANEDIOL, Beta-2-microglobulin, GLYCEROL, ...
著者Rizkallah, P.J, Cole, D.K, Fuller, A, Sewell, A.K.
登録日2014-07-15
公開日2015-04-08
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (1.77 Å)
主引用文献A molecular switch in immunodominant HIV-1-specific CD8 T-cell epitopes shapes differential HLA-restricted escape.
Retrovirology, 12, 2015
1XR9
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BU of 1xr9 by Molmil
Crystal Structures of HLA-B*1501 in Complex with Peptides from Human UbcH6 and Epstein-Barr Virus EBNA-3
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Roder, G, Blicher, T, Johannessen, B.R, Kristensen, O, Buus, S, Gajhede, M.
登録日2004-10-14
公開日2005-04-14
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.788 Å)
主引用文献Crystal structures of two peptide-HLA-B*1501 complexes; structural characterization of the HLA-B62 supertype
Acta Crystallogr.,Sect.D, 62, 2006
5VUE
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HLA-B*57:01 presenting LTVQVARVW
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-19
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
3LKQ
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Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1977 strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3VH8
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KIR3DL1 in complex with HLA-B*5701
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Vivian, J.P, Rossjohn, J.
登録日2011-08-24
公開日2011-10-26
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Killer cell immunoglobulin-like receptor 3DL1-mediated recognition of human leukocyte antigen B
Nature, 479, 2011
7RZJ
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CRYSTAL STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PHOSPHOPEPTIDE
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-7 alpha chain, ...
著者Patskovsky, Y, Patskovska, L, Nyovanie, S, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
登録日2021-08-27
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
7S8F
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STRUCTURE OF HLA-B*07:02 IN COMPLEX WITH MLL(747-755) PEPTIDE AND BOUND GLYCEROL
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Patskovsky, Y, Nyovanie, S, Patskovska, L, Natarajan, A, Joshi, B, Morin, B, Brittsan, C, Huber, O, Gordon, S, Michelet, X, Schmitzberger, F, Stein, R, Findeis, M, Hurwitz, A, Van Dijk, M, Buell, J, Underwood, D, Krogsgaard, M.
登録日2021-09-17
公開日2022-11-02
最終更新日2023-10-18
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Molecular mechanism of phosphopeptide neoantigen immunogenicity.
Nat Commun, 14, 2023
3BP7
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BU of 3bp7 by Molmil
The high resolution crystal structure of HLA-B*2709 in complex with a Cathepsin A signal sequence peptide, pCatA
分子名称: Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ...
著者Kumar, P, Vahedi-Faridi, A, Saenger, W, Uchanska-Ziegler, B, Ziegler, A.
登録日2007-12-18
公開日2008-12-23
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structural basis for T cell alloreactivity among three HLA-B14 and HLA-B27 antigens
J.Biol.Chem., 284, 2009
3B6S
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BU of 3b6s by Molmil
Crystal Structure of hla-b*2705 Complexed with the Citrullinated Vasoactive Intestinal Peptide Type 1 Receptor (vipr) Peptide (residues 400-408)
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-27 alpha chain, ...
著者Beltrami, A, Rossmann, M, Fiorillo, M.T, Sorrentino, R, Saenger, W, Ziegler, A, Uchanska-Ziegler, A.
登録日2007-10-29
公開日2008-07-22
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Citrullination-dependent Differential Presentation of a Self-peptide by HLA-B27 Subtypes.
J.Biol.Chem., 283, 2008
5IEK
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BU of 5iek by Molmil
Structure of HLA-B*40:02 in complex with the endogenous peptide REFSKEPEL
分子名称: ARG-GLU-PHE-SER-LYS-GLU-PRO-GLU-LEU, Beta-2-microglobulin, HLA class I histocompatibility antigen, ...
著者Alpizar, A, Marcilla, M, Santiago, C.
登録日2016-02-25
公開日2016-12-07
最終更新日2019-10-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Structure of HLA-B*40:02 in complex with the endogenous peptide REFSKEPEL
To Be Published
3LKP
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Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1972 strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
3X12
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Crystal structure of HLA-B*57:01.I80N
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-57 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2014-10-24
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
3X13
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Crystal structure of HLA-B*0801.N80I
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-8 alpha chain, ...
著者Vivian, J.P, Rossjohn, J.
登録日2014-10-24
公開日2014-12-24
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The interaction of KIR3DL1*001 with HLA class I molecules is dependent upon molecular microarchitecture within the Bw4 epitope
J.Immunol., 194, 2015
2AXF
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The Immunogenicity of a Viral Cytotoxic T Cell Epitope is controlled by its MHC-bound Conformation
分子名称: 10-mer peptide from BZLF1 trans-activator protein, ACETIC ACID, Beta-2-microglobulin, ...
著者Tynan, F.E, Elhassen, D, Purcell, A.W, Burrows, J.M, Borg, N.A, Miles, J.J, Williamson, N.A, Green, K.J, Tellam, J, Kjer-Nielsen, L, McCluskey, J, Rossjohn, J, Burrows, S.R.
登録日2005-09-05
公開日2005-11-29
最終更新日2017-10-11
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The immunogenicity of a viral cytotoxic T cell epitope is controlled by its MHC-bound conformation
J.Exp.Med., 202, 2005
4PR5
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BU of 4pr5 by Molmil
Crystal structure of a HLA-B*35:01-HPVG-D5
分子名称: Beta-2-microglobulin, Epstein-Barr nuclear antigen 1, HLA class I histocompatibility antigen, ...
著者Yu Chih, L, Rossjohn, J, Gras, S.
登録日2014-03-05
公開日2014-04-16
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A Molecular Basis for the Interplay between T Cells, Viral Mutants, and Human Leukocyte Antigen Micropolymorphism.
J.Biol.Chem., 289, 2014
5VWD
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HLA-B*57:03 presenting LTVQVARVW
分子名称: Beta-2-microglobulin, MHC class I antigen, Noamer peptide: LEU-THR-VAL-GLN-VAL-ALA-ARG-VAL-TRP
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-21
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
3L3D
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Crystal structure of HLA-B*4402 in complex with the F3A mutant of a self-peptide derived from DPA*0201
分子名称: ACETATE ION, Beta-2-microglobulin, GLYCEROL, ...
著者Theodossis, A, Ely, L.K, Rossjohn, J.
登録日2009-12-16
公開日2010-03-16
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Constraints within major histocompatibility complex class I restricted peptides: presentation and consequences for T-cell recognition
Proc.Natl.Acad.Sci.USA, 107, 2010
3SKM
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Crystal structure of the HLA-B8FLRGRAYVL, mutant G8V of the FLR peptide
分子名称: Beta-2-microglobulin, Epstein-Barr nuclear antigen 3, HLA class I histocompatibility antigen, ...
著者Gras, S, Wilmann, P.G, Zhenjun, C, Hanim, H, Yu Chih, L, Kjer-Nielsen, L, Purcell, A.W, Burrows, S.R, Mccluskey, J, Rossjohn, J.
登録日2011-06-22
公開日2012-02-29
最終更新日2023-09-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A structural basis for varied alpha-beta TCR usage against an immunodominant EBV antigen restricted to a HLA-B8 molecule.
J.Immunol., 188, 2012
5VWF
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HLA-B*58:03 presenting LTVQVARVY
分子名称: Beta-2-microglobulin, MHC class I antigen, Nonamer peptide: LEU-THR-VAL-GLN-VAL-ALA-ARG-VAL-TYR
著者Pymm, P, Rossjohn, J, Vivian, J.P.
登録日2017-05-21
公開日2018-10-03
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.
Nat Commun, 9, 2018
3LKO
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Crystal Structure of HLA B*3501 in complex with influenza NP418 epitope from 1934 strain
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-35 alpha chain, ...
著者Gras, S, Kedzierski, L, Valkenburg, S.A, Liu, Y.C, Denholm, J, Richards, M, Rimmelzwaan, G.F, Doherty, P.C, Turner, S.J, Rossjohn, J, Kedzierska, K.
登録日2010-01-27
公開日2010-07-07
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Cross-reactive CD8+ T-cell immunity between the pandemic H1N1-2009 and H1N1-1918 influenza A viruses.
Proc.Natl.Acad.Sci.USA, 107, 2010
4O2C
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An Nt-acetylated peptide complexed with HLA-B*3901
分子名称: Beta-2-microglobulin, HLA class I histocompatibility antigen, B-39 alpha chain, ...
著者Sun, M, Liu, J, Qi, J, Tefsen, B, Shi, Y, Yan, J, Gao, G.F.
登録日2013-12-17
公開日2014-07-23
最終更新日2023-11-08
実験手法X-RAY DIFFRACTION (1.802 Å)
主引用文献N alpha-terminal acetylation for T cell recognition: molecular basis of MHC class I-restricted n alpha-acetylpeptide presentation
J.Immunol., 192, 2014

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