5T6Y

HLA-B*57:01 presenting TSTFEDVKILAF

Summary for 5T6Y

Entry DOI	10.2210/pdb5t6y/pdb
Related	5T6W 5T6X 5T6Z 5T70
Descriptor	HLA class I histocompatibility antigen, B-57 alpha chain, Beta-2-microglobulin, Decapeptide: THR-SER-THR-PHE-GLU-ASP-VAL-LYS-ILE-LEU-ALA-PHE, ... (6 entities in total)
Functional Keywords	human leukocyte antigen immunoglobulin domain antigen presentation, immune system
Biological source	Homo sapiens (Human) More
Cellular location	Membrane; Single-pass type I membrane protein: P18465 Secreted . Note=(Microbial infection) In the presence of M: P61769
Total number of polymer chains	3
Total formula weight	45191.21
Authors	Pymm, P.,Rossjohn, J.,Vivian, J.P. (deposition date: 2016-09-02, release date: 2017-03-01, Last modification date: 2023-10-04)
Primary citation	Pymm, P.,Illing, P.T.,Ramarathinam, S.H.,O'Connor, G.M.,Hughes, V.A.,Hitchen, C.,Price, D.A.,Ho, B.K.,McVicar, D.W.,Brooks, A.G.,Purcell, A.W.,Rossjohn, J.,Vivian, J.P. MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape. Nat. Struct. Mol. Biol., 24:387-394, 2017 Cited by PubMed: 28218747 DOI: 10.1038/nsmb.3381 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.76 Å)

Structure validation