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PDB: 15 件
5QU8
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Crystal Structure of symmetric swapped human Nck SH3.1 domain, 0.93A, orthorhombic form IV
分子名称: Cytoplasmic protein NCK1, SODIUM ION
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (0.93 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU3
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Crystal Structure of domain swapped human Nck SH3.1, 1.01A, monoclinic
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.02 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU2
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Crystal Structure of human Nck SH3.1 in complex with peptide PPPVPNPDY
分子名称: ACE-PRO-PRO-PRO-VAL-PRO-ASN-PRO-ASP-TYR-NH2, Cytoplasmic protein NCK1, SULFATE ION
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.04 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU4
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Crystal Structure of swapped human Nck SH3.1 domain, 1.05A, orthorhombic form I
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.05 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU1
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BU of 5qu1 by Molmil
Crystal Structure of the monomeric human Nck SH3.1 domain, triclinic, 1.08A
分子名称: Cytoplasmic protein NCK1, SULFATE ION
著者Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.08 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU5
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BU of 5qu5 by Molmil
Domain Swap in the first SH3 domain of human Nck1
分子名称: Cytoplasmic protein NCK1
著者Burger, D, Ruf, A, Benz, J, Schlatter, D, Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.11 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
5QU7
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BU of 5qu7 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.3A, orthorhombic form III
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.27 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
2CI9
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BU of 2ci9 by Molmil
Nck1 SH2-domain in complex with a dodecaphosphopeptide from EPEC protein Tir
分子名称: CYTOPLASMIC PROTEIN NCK1, TRANSLOCATED INTIMIN RECEPTOR
著者Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W.
登録日2006-03-17
公開日2006-04-24
最終更新日2024-05-01
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains.
J.Biol.Chem., 281, 2006
5QUA
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Crystal Structure of swapped human Nck SH3.1 domain, 1.5A, C2221
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.51 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
2CI8
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BU of 2ci8 by Molmil
sh2 domain of human nck1 adaptor protein - uncomplexed
分子名称: CYTOPLASMIC PROTEIN NCK1, PENTAETHYLENE GLYCOL, SULFATE ION
著者Frese, S, Schubert, W.-D, Findeis, A.C, Marquardt, T, Roske, Y.S, Stradal, T.E.B, Heinz, D.W.
登録日2006-03-17
公開日2006-04-24
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献The Phosphotyrosine Peptide Binding Specificity of Nck1 and Nck2 Src Homology 2 Domains.
J.Biol.Chem., 281, 2006
5QU6
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BU of 5qu6 by Molmil
Crystal Structure of swapped human Nck SH3.1 domain, 1.8A, triclinic
分子名称: Cytoplasmic protein NCK1
著者Rudolph, M.G.
登録日2019-12-13
公開日2020-02-12
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (1.816 Å)
主引用文献Small molecule AX-024 reduces T cell proliferation independently of CD3ε/Nck1 interaction, which is governed by a domain swap in the Nck1-SH3.1 domain.
J.Biol.Chem., 295, 2020
2CUB
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BU of 2cub by Molmil
Solution structure of the SH3 domain of the human cytoplasmic protein Nck1
分子名称: Cytoplasmic protein NCK1
著者Ohnishi, S, Kigawa, T, Sato, M, Tomizawa, T, Koshiba, S, Inoue, M, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI)
登録日2005-05-26
公開日2005-11-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of the SH3 domain of the human cytoplasmic protein Nck1
To be Published
2JW4
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BU of 2jw4 by Molmil
NMR solution structure of the N-terminal SH3 domain of human Nckalpha
分子名称: Cytoplasmic protein NCK1
著者Santiveri, C.M, Borroto, A, Simon, L, Rico, M, Ortiz, A.R, Alarcon, B, Jimenez, M.
登録日2007-10-05
公開日2008-08-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Interaction between the N-terminal SH3 domain of Nckalpha and CD3epsilon-derived peptides: Non-canonical and canonical recognition motifs
BIOCHEM.BIOPHYS.ACTA PROTEINS & PROTEOMICS, 1794, 2009
2JS2
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BU of 2js2 by Molmil
Solution structure of first SH3 domain of adaptor Nck
分子名称: Cytoplasmic protein NCK1
著者Hake, M.J, Choowongkomon, K, Carlin, C.R, Sonnichsen, F.D.
登録日2007-06-29
公開日2008-02-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Specificity determinants of a novel Nck interaction with the juxtamembrane domain of the epidermal growth factor receptor.
Biochemistry, 47, 2008
2JS0
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Solution structure of second SH3 domain of adaptor Nck
分子名称: Cytoplasmic protein NCK1
著者Hake, M.J, Choowongkomon, K, Carlin, C.R, Sonnichsen, F.D.
登録日2007-06-29
公開日2008-02-26
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Specificity determinants of a novel Nck interaction with the juxtamembrane domain of the epidermal growth factor receptor.
Biochemistry, 47, 2008

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件を2024-07-31に公開中

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