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PDB: 68 件
1VQ6
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BU of 1vq6 by Molmil
The structure of c-hpmn and CCA-PHE-CAP-BIO bound to the large ribosomal subunit of haloarcula marismortui
分子名称: 23S ribosomal rna, 5'-R(*CP*(5AA)*(HFA))-3', 5'-R(*CP*CP*AP*(PHE)*(ACA)*(BTN))-3', ...
著者Schmeing, T.M, Steitz, T.A.
登録日2004-12-16
公開日2005-11-29
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献An induced-fit mechanism to promote peptide bond formation and exclude hydrolysis of peptidyl-tRNA.
Nature, 438, 2005
3OW2
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BU of 3ow2 by Molmil
Crystal Structure of Enhanced Macrolide Bound to 50S Ribosomal Subunit
分子名称: (2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-15-oxo-11-[(3,4,6-trideoxy-3-{[3-(1-{(1S,2R)-1-(fluoromethyl)-2-hydroxy-2-[4-(methylsulfonyl)phenyl]ethyl}-1H-1,2,3-triazol-4-yl)propyl](methyl)amino}-beta-D-xylo-hexopyranosyl)oxy]-1-oxa-6-azacyclopentadecan-13-yl 2,6-dideoxy-3-C-methyl-3-O-methyl-alpha-L-ribo-hexopyranoside, 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, ...
著者Kanyo, Z.F.
登録日2010-09-17
公開日2012-06-20
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献

3CCE
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BU of 3cce by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535A
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-25
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
3CD6
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BU of 3cd6 by Molmil
Co-cystal of large Ribosomal Subunit mutant G2616A with CC-Puromycin
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-26
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
3CCU
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BU of 3ccu by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482C
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-26
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
1YIT
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BU of 1yit by Molmil
Crystal Structure Of Virginiamycin M and S Bound To The 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S RIBOSOMAL RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-13
公開日2005-04-26
最終更新日2012-12-12
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
Cell(Cambridge,Mass.), 121, 2005
1YJ9
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BU of 1yj9 by Molmil
Crystal Structure Of The Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui Containing a three residue deletion in L22
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-13
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005
3CMA
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BU of 3cma by Molmil
The structure of CCA and CCA-Phe-Cap-Bio bound to the large ribosomal subunit of Haloarcula marismortui
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Simonovic, M, Steitz, T.A.
登録日2008-03-21
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
1M90
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BU of 1m90 by Molmil
Co-crystal structure of CCA-Phe-caproic acid-biotin and sparsomycin bound to the 50S ribosomal subunit
分子名称: 23S RRNA, 5S RRNA, 6-AMINOHEXANOIC ACID, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2002-07-26
公開日2002-09-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Structural insights into peptide bond formation.
Proc.Natl.Acad.Sci.USA, 99, 2002
3G71
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BU of 3g71 by Molmil
Co-crystal structure of Bruceantin bound to the large ribosomal subunit
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Gurel, G, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2009-02-09
公開日2009-04-28
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.85 Å)
主引用文献U2504 determines the species specificity of the A-site cleft antibiotics: the structures of tiamulin, homoharringtonine, and bruceantin bound to the ribosome.
J.Mol.Biol., 389, 2009
1QVG
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BU of 1qvg by Molmil
Structure of CCA oligonucleotide bound to the tRNA binding sites of the large ribosomal subunit of Haloarcula marismortui
分子名称: 23S ribosomal rna, 50S RIBOSOMAL PROTEIN L10E, 50S ribosomal protein L13P, ...
著者Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-27
公開日2003-11-11
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of deacylated tRNA mimics bound to the E site of the large ribosomal subunit
RNA, 9, 2003
3CCV
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BU of 3ccv by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2616A
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-26
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
3CCL
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BU of 3ccl by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation U2535C. Density for Anisomycin is visible but not included in model.
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-26
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
2OTJ
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BU of 2otj by Molmil
13-deoxytedanolide bound to the large subunit of Haloarcula marismortui
分子名称: 13-DEOXYTEDANOLIDE, 23S ribosomal RNA, 50S ribosomal protein L10E, ...
著者Blaha, G, Schroeder, S.J, Tirado-Rives, J.
登録日2007-02-08
公開日2007-04-03
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole.
J.Mol.Biol., 367, 2007
3CCQ
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BU of 3ccq by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488U
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-26
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
2QEX
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BU of 2qex by Molmil
Negamycin Binds to the Wall of the Nascent Chain Exit Tunnel of the 50S Ribosomal Subunit
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10e, 50S ribosomal protein L11P, ...
著者Schroeder, S.J, Blaha, G.
登録日2007-06-26
公開日2008-09-30
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Negamycin binds to the wall of the nascent chain exit tunnel of the 50S ribosomal subunit.
Antimicrob.Agents Chemother., 51, 2007
1YJW
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BU of 1yjw by Molmil
Crystal Structure Of Quinupristin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10, 50S ribosomal protein L10e, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-15
公開日2005-04-26
最終更新日2023-06-14
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of Mlsbk Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance.
Cell(Cambridge,Mass.), 121, 2005
3I56
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BU of 3i56 by Molmil
Co-crystal structure of Triacetyloleandomcyin Bound to the Large Ribosomal Subunit
分子名称: 23S ribosomal RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Gurel, G, Blaha, G, Steitz, T.A, Moore, P.B.
登録日2009-07-03
公開日2010-03-09
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structures of triacetyloleandomycin and mycalamide A bind to the large ribosomal subunit of Haloarcula marismortui.
Antimicrob.Agents Chemother., 53, 2009
3CCS
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BU of 3ccs by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation G2482A
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-26
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
1Q81
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BU of 1q81 by Molmil
Crystal Structure of minihelix with 3' puromycin bound to A-site of the 50S ribosomal subunit.
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Structural Insights into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
3CME
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BU of 3cme by Molmil
The Structure of CA and CCA-PHE-CAP-BIO Bound to the Large Ribosomal Subunit of Haloarcula Marismortui
分子名称: 50S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Simonovic, M, Steitz, T.A.
登録日2008-03-21
公開日2008-09-23
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (2.95 Å)
主引用文献Peptidyl-CCA deacylation on the ribosome promoted by induced fit and the O3'-hydroxyl group of A76 of the unacylated A-site tRNA.
Rna, 14, 2008
1Q82
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BU of 1q82 by Molmil
Crystal Structure of CC-Puromycin bound to the A-site of the 50S ribosomal subunit
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.98 Å)
主引用文献Structural Insights Into Peptide Bond Formation
Proc.Natl.Acad.Sci.USA, 99, 2002
1Q86
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BU of 1q86 by Molmil
Crystal structure of CCA-Phe-cap-biotin bound simultaneously at half occupancy to both the A-site and P-site of the the 50S ribosomal Subunit.
分子名称: 23S ribosomal rna, 50S ribosomal protein L13P, 50S ribosomal protein L14P, ...
著者Hansen, J.L, Schmeing, T.M, Moore, P.B, Steitz, T.A.
登録日2003-08-20
公開日2003-10-07
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structural insights into peptide bond formation.
Proc.Natl.Acad.Sci.USA, 99, 2002
3CCR
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BU of 3ccr by Molmil
Structure of Anisomycin resistant 50S Ribosomal Subunit: 23S rRNA mutation A2488C. Density for anisomycin is visible but not included in the model.
分子名称: 23S RIBOSOMAL RNA, 50S ribosomal protein L10E, 50S ribosomal protein L10e, ...
著者Blaha, G, Gurel, G.
登録日2008-02-26
公開日2008-05-20
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Mutations outside the anisomycin-binding site can make ribosomes drug-resistant.
J.Mol.Biol., 379, 2008
1YJN
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BU of 1yjn by Molmil
Crystal Structure Of Clindamycin Bound To The G2099A Mutant 50S Ribosomal Subunit Of Haloarcula Marismortui
分子名称: 23S Ribosomal RNA, 50S RIBOSOMAL PROTEIN L10E, 50S RIBOSOMAL PROTEIN L11P, ...
著者Tu, D, Blaha, G, Moore, P.B, Steitz, T.A.
登録日2005-01-14
公開日2005-04-26
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (3 Å)
主引用文献Structures of MLSBK antibiotics bound to mutated large ribosomal subunits provide a structural explanation for resistance.
Cell(Cambridge,Mass.), 121, 2005

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