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PDB: 260 件
6PBX
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Single particle cryo-EM structure of the voltage-gated K+ channel Eag1 3-13 deletion mutant bound to calmodulin (conformation 2)
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Whicher, J.R, MacKinnon, R.
登録日2019-06-14
公開日2019-09-18
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (4 Å)
主引用文献Regulation of Eag1 gating by its intracellular domains.
Elife, 8, 2019
8J07
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96nm repeat of human respiratory doublet microtubule and associated axonemal complexes
分子名称: ACTA2, Axonemal dynein light intermediate polypeptide 1, Calaxin, ...
著者Gui, M, Brown, A.
登録日2023-04-09
公開日2023-07-26
最終更新日2023-08-02
実験手法ELECTRON MICROSCOPY (4.1 Å)
主引用文献Axonemal structures reveal mechanoregulatory and disease mechanisms.
Nature, 618, 2023
6JIU
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Structure of RyR2 (F/A/C/L-Ca2+/Ca2+CaM dataset)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Gong, D.S, Chi, X.M, Zhou, G.W, Huang, G.X.Y, Lei, J.L, Yan, N.
登録日2019-02-23
公開日2019-07-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Modulation of cardiac ryanodine receptor 2 by calmodulin.
Nature, 572, 2019
6X35
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Pig R615C RyR1 in complex with CaM, EGTA (class 1, open)
分子名称: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
著者Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
登録日2020-05-21
公開日2021-01-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6X33
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Wt pig RyR1 in complex with apoCaM, EGTA condition (class 3, open)
分子名称: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor, ...
著者Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
登録日2020-05-21
公開日2021-01-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
6JII
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Structure of RyR2 (F/A/C/L-Ca2+/apo-CaM-M dataset)
分子名称: ADENOSINE-5'-TRIPHOSPHATE, CAFFEINE, CALCIUM ION, ...
著者Gong, D.S, Chi, X.M, Zhou, G.W, Huang, G.X.Y, Lei, J.L, Yan, N.
登録日2019-02-21
公開日2019-07-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.2 Å)
主引用文献Modulation of cardiac ryanodine receptor 2 by calmodulin.
Nature, 572, 2019
6JV2
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Structure of RyR2 (P/L-Ca2+/Ca2+-CaM dataset)
分子名称: CALCIUM ION, Calmodulin-1, RyR2, ...
著者Gong, D.S, Chi, X.M, Zhou, G.W, Huang, G.X.Y, Lei, J.L, Yan, N.
登録日2019-04-15
公開日2019-07-17
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (4.4 Å)
主引用文献Modulation of cardiac ryanodine receptor 2 by calmodulin.
Nature, 572, 2019
7WJI
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BU of 7wji by Molmil
Architecture of the human NALCN channelosome
分子名称: Calmodulin-1, Protein unc-79 homolog, Protein unc-80 homolog, ...
著者Wu, J.P, Yan, Z, Zhou, L, Liu, H, Zhao, Q.
登録日2022-01-06
公開日2022-04-20
最終更新日2024-06-26
実験手法ELECTRON MICROSCOPY (4.5 Å)
主引用文献Architecture of the human NALCN channelosome.
Cell Discov, 8, 2022
8OE0
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Cryo-EM structure of a pre-dimerized murine IL-12 complete extracellular signaling complex (Class 2).
分子名称: 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Interleukin-12 receptor subunit beta-1,Death-associated protein kinase 1, ...
著者Felix, J, Bloch, Y, Savvides, S.N.
登録日2023-03-10
公開日2024-02-07
最終更新日2024-05-01
実験手法ELECTRON MICROSCOPY (4.6 Å)
主引用文献Structures of complete extracellular receptor assemblies mediated by IL-12 and IL-23.
Nat.Struct.Mol.Biol., 31, 2024
6CNO
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Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state II
分子名称: CALCIUM ION, Calmodulin-1, Intermediate conductance calcium-activated potassium channel protein 4
著者Lee, C.H, MacKinnon, R.
登録日2018-03-08
公開日2018-05-02
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Activation mechanism of a human SK-calmodulin channel complex elucidated by cryo-EM structures.
Science, 360, 2018
6X36
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Pig R615C RyR1 in complex with CaM, EGTA (class 3, closed)
分子名称: Calmodulin-1, Peptidyl-prolyl cis-trans isomerase FKBP1B, Ryanodine Receptor
著者Woll, K.W, Haji-Ghassemi, O, Van Petegem, F.
登録日2020-05-21
公開日2021-01-13
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (4.7 Å)
主引用文献Pathological conformations of disease mutant Ryanodine Receptors revealed by cryo-EM.
Nat Commun, 12, 2021
8EP0
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Eag Kv channel with voltage sensor in the intermediate conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (4.9 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
8EP1
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Eag Kv channel with voltage sensor in the down conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily H member 1
著者Mandala, V.S, MacKinnon, R.
登録日2022-10-04
公開日2022-11-16
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (5.4 Å)
主引用文献Voltage-sensor movements in the Eag Kv channel under an applied electric field.
Proc.Natl.Acad.Sci.USA, 119, 2022
8SIM
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KCNQ1 with voltage sensor in the intermediate conformation
分子名称: CALCIUM ION, Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
著者Mandala, V.S, MacKinnon, R.
登録日2023-04-16
公開日2023-05-31
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (6.2 Å)
主引用文献The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel.
Proc.Natl.Acad.Sci.USA, 120, 2023
8SIN
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BU of 8sin by Molmil
KCNQ1 with voltage sensor in the down conformation
分子名称: Calmodulin-1, Potassium voltage-gated channel subfamily KQT member 1
著者Mandala, V.S, MacKinnon, R.
登録日2023-04-16
公開日2023-05-31
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (6.8 Å)
主引用文献The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel.
Proc.Natl.Acad.Sci.USA, 120, 2023
3J41
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BU of 3j41 by Molmil
Pseudo-atomic model of the Aquaporin-0/Calmodulin complex derived from electron microscopy
分子名称: CALCIUM ION, Calmodulin, Lens fiber major intrinsic protein
著者Reichow, S.L, Clemens, D.M, Freites, J.A, Nemeth-Cahalan, K.L, Heyden, M, Tobias, D.J, Hall, J.E, Gonen, T.
登録日2013-05-31
公開日2013-07-31
最終更新日2024-02-21
実験手法ELECTRON MICROSCOPY (25 Å)
主引用文献Allosteric mechanism of water-channel gating by Ca(2+)-calmodulin.
Nat.Struct.Mol.Biol., 20, 2013
2K0F
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BU of 2k0f by Molmil
Calmodulin complexed with calmodulin-binding peptide from smooth muscle myosin light chain kinase
分子名称: 19-mer peptide from Myosin light chain kinase, CALCIUM ION, calmodulin
著者Gsponer, J, Christodoulou, J, Cavalli, A, Bui, J.M, Richter, B, Dobson, C.M, Vendruscolo, M.
登録日2008-02-02
公開日2008-06-10
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献A coupled equilibrium shift mechanism in calmodulin-mediated signal transduction
Structure, 16, 2008
2M0K
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3D Structure of Calmodulin and Calmodulin Binding Domain of Rat Olfactory Cyclic Nucleotide-Gated Ion Channel
分子名称: CALCIUM ION, Calmodulin, Peptide from Cyclic nucleotide-gated olfactory channel
著者Deli, I, Chyan, C.
登録日2012-10-29
公開日2013-10-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel.
J.Biomol.Struct.Dyn., 31, 2013
1NKF
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CALCIUM-BINDING PEPTIDE, NMR, 30 STRUCTURES
分子名称: CALCIUM-BINDING HEXADECAPEPTIDE, LANTHANUM (III) ION
著者Sticht, H, Ejchart, A.
登録日1998-03-09
公開日1999-02-16
最終更新日2022-02-23
実験手法SOLUTION NMR
主引用文献Alpha-helix nucleation by a calcium-binding peptide loop.
Proc.Natl.Acad.Sci.USA, 96, 1999
1J7O
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Solution structure of Calcium-calmodulin N-terminal domain
分子名称: CALCIUM ION, Calmodulin
著者Chou, J.J, Klee, C.B, Bax, A.
登録日2001-05-17
公開日2001-11-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains.
Nat.Struct.Biol., 8, 2001
6Y94
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Ca2+-bound Calmodulin mutant N53I
分子名称: CALCIUM ION, Calmodulin
著者Holt, C, Nielsen, L.H, Lau, K, Brohus, M, Sorensen, A.B, Larsen, K.T, Sommer, C, Petegem, F.V, Overgaard, M.T, Wimmer, R.
登録日2020-03-06
公開日2020-04-29
最終更新日2024-06-19
実験手法SOLUTION NMR
主引用文献The arrhythmogenic N53I variant subtly changes the structure and dynamics in the calmodulin N-terminal domain, altering its interaction with the cardiac ryanodine receptor.
J.Biol.Chem., 295, 2020
2M0J
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3D Structure of Calmodulin and Calmodulin binding domain of Olfactory cyclic nucleotide-gated ion channel complex
分子名称: CALCIUM ION, Calmodulin, Peptide from Cyclic nucleotide-gated olfactory channel
著者Deli, I, Chyan, C.
登録日2012-10-29
公開日2013-10-30
最終更新日2024-05-01
実験手法SOLUTION NMR
主引用文献Binding orientation and specificity of calmodulin to rat olfactory cyclic nucleotide-gated ion channel
J.Biomol.Struct.Dyn., 31, 2013
1J7P
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Solution structure of Calcium calmodulin C-terminal domain
分子名称: CALCIUM ION, Calmodulin
著者Chou, J.J, Klee, C.B, Bax, A.
登録日2001-05-17
公開日2001-11-07
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution structure of Ca(2+)-calmodulin reveals flexible hand-like properties of its domains.
Nat.Struct.Biol., 8, 2001
8DGH
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NMR Structure of calmodulin bound to C-terminal site in the beta-subunit of cyclic nucleotide-gated channel
分子名称: Calmodulin-1, Cyclic nucleotide-gated cation channel beta-1
著者Bej, A, Ames, J.B.
登録日2022-06-23
公開日2022-12-14
最終更新日2024-05-15
実験手法SOLUTION NMR
主引用文献NMR Structures of Calmodulin Bound to Two Separate Regulatory Sites in the Retinal Cyclic Nucleotide-Gated Channel.
Biochemistry, 61, 2022
2MG5
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Solution Structure of Calmodulin bound to the target peptide of Endothelial Nitrogen Oxide Synthase phosphorylated at Thr495
分子名称: Calmodulin, target peptide
著者Piazza, M, Dieckmann, T.
登録日2013-10-28
公開日2014-03-05
最終更新日2023-06-14
実験手法SOLUTION NMR
主引用文献Solution structure of calmodulin bound to the target Peptide of endothelial nitric oxide synthase phosphorylated at thr495.
Biochemistry, 53, 2014

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