8SIN

KCNQ1 with voltage sensor in the down conformation

Summary for 8SIN

• Entry DOI: 10.2210/pdb8sin/pdb
• EMDB information: 40510
• Descriptor: Potassium voltage-gated channel subfamily KQT member 1, Calmodulin-1 (2 entities in total)
• Functional Keywords: voltage-gated potassium channel, membrane protein
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 8
• Total formula weight: 320444.48

Authors

Mandala, V.S.,MacKinnon, R. (deposition date: 2023-04-16, release date: 2023-05-31)

• Primary citation: Mandala, V.S.,MacKinnon, R.; The membrane electric field regulates the PIP 2 -binding site to gate the KCNQ1 channel.; Proc.Natl.Acad.Sci.USA, 120:e2301985120-e2301985120, 2023; PubMed: 37192161; DOI: 10.1073/pnas.2301985120

Experimental method

ELECTRON MICROSCOPY (6.8 Å)