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PDB: 146 件

6T7I
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Structure of yeast 80S ribosome stalled on the CGA-CGA inhibitory codon combination.
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Buschauer, R, Cheng, J, Berninghausen, O, Becker, R, Beckmann, R.
登録日2019-10-22
公開日2019-12-25
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.2 Å)
主引用文献Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts.
Embo J., 39, 2020
5DC3
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BU of 5dc3 by Molmil
Complex of yeast 80S ribosome with non-modified eIF5A
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-23
公開日2016-06-01
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Crystal Structure of Hypusine-Containing Translation Factor eIF5A Bound to a Rotated Eukaryotic Ribosome.
J.Mol.Biol., 428, 2016
5LYB
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Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCPmn
分子名称: 18S rRNA, 25S rRNA, 40S Ribosomal Protein S12, ...
著者Melnikov, S, Mailliot, J.
登録日2016-09-26
公開日2016-11-23
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
6S47
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Saccharomyces cerevisiae 80S ribosome bound with ABCF protein New1
分子名称: 18S rRNA (1707-MER), 28S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Kasari, V, Pochopien, A.A, Margus, T, Murina, V, Turnbull, K, Zhou, Y, Nissan, T, Graf, M, Novacek, J, Atkinson, G.C, Johansson, M.J.O, Wilson, D.N, Hauryliuk, V.
登録日2019-06-26
公開日2019-07-24
最終更新日2019-10-23
実験手法ELECTRON MICROSCOPY (3.28 Å)
主引用文献A role for the Saccharomyces cerevisiae ABCF protein New1 in translation termination/recycling.
Nucleic Acids Res., 47, 2019
4U53
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Crystal structure of Deoxynivalenol bound to the yeast 80S ribosome
分子名称: (3beta,7alpha)-3,7,15-trihydroxy-12,13-epoxytrichothec-9-en-8-one, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
5NDV
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BU of 5ndv by Molmil
Crystal structure of Paromomycin bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G.
登録日2017-03-09
公開日2017-12-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
7B7D
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BU of 7b7d by Molmil
Yeast 80S ribosome bound to eEF3 and A/A- and P/P-tRNAs
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Ranjan, N, Pochopien, A.A, Wu, C.C, Beckert, B, Blanchet, S, Green, R, Rodnina, M.V, Wilson, D.N.
登録日2020-12-10
公開日2021-03-10
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献eEF3 promotes late stages of tRNA translocation including E-tRNA release from the ribosome
To Be Published
6SV4
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BU of 6sv4 by Molmil
The cryo-EM structure of SDD1-stalled collided trisome.
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Tesina, P, Buschauer, R, Cheng, J, Becker, T, Beckmann, R.
登録日2019-09-17
公開日2020-03-04
最終更新日2020-04-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献RQT complex dissociates ribosomes collided on endogenous RQC substrate SDD1.
Nat.Struct.Mol.Biol., 27, 2020
5TGA
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BU of 5tga by Molmil
Crystal structure of the S.cerevisiae 80S ribosome in complex with the A-site bound aminoacyl-tRNA analog ACCA-Pro
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 3'-amino-3'-deoxyadenosine 5'-(dihydrogen phosphate), ...
著者Melnikov, S, Mailliot, J.
登録日2016-09-27
公開日2016-11-23
最終更新日2016-12-14
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Molecular insights into protein synthesis with proline residues.
EMBO Rep., 17, 2016
5T62
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Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis: 60S-Nmd3-Tif6-Lsg1 Complex
分子名称: 25S Ribosomal RNA, 5.8S Ribosomal RNA, 5S Ribosomal RNA, ...
著者Malyutin, A.G, Musalgaonkar, S, Patchett, S, Frank, J, Johnson, A.W.
登録日2016-09-01
公開日2017-02-08
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Nmd3 is a structural mimic of eIF5A, and activates the cpGTPase Lsg1 during 60S ribosome biogenesis.
EMBO J., 36, 2017
6RI5
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BU of 6ri5 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
分子名称: 25S RNA, 5.8S rRNA, 5S rRNA, ...
著者Kargas, V, Warren, A.J.
登録日2019-04-23
公開日2019-06-26
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.3 Å)
主引用文献Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
5DGF
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BU of 5dgf by Molmil
Complex of yeast 80S ribosome with hypusine-containing/non-modified eIF5A and/or a peptidyl-tRNA analog
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-27
公開日2016-12-14
最終更新日2024-05-29
実験手法X-RAY DIFFRACTION (3.3 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
6Z6J
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BU of 6z6j by Molmil
Cryo-EM structure of yeast Lso2 bound to 80S ribosomes under native condition
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
登録日2020-05-28
公開日2020-07-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6Z6K
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BU of 6z6k by Molmil
Cryo-EM structure of yeast reconstituted Lso2 bound to 80S ribosomes
分子名称: 18S rRNA, 25S rRNA, 40S ribosomal protein S0-A, ...
著者Wells, J.N, Buschauer, R, Mackens-Kiani, T, Best, K, Kratzat, H, Berninghausen, O, Becker, T, Cheng, J, Beckmann, R.
登録日2020-05-28
公開日2020-07-29
最終更新日2024-05-22
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and function of yeast Lso2 and human CCDC124 bound to hibernating ribosomes.
Plos Biol., 18, 2020
6R86
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BU of 6r86 by Molmil
Yeast Vms1-60S ribosomal subunit complex (post-state)
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R.
登録日2019-03-31
公開日2019-07-31
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
6QT0
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BU of 6qt0 by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Kargas, V, Warren, A.J.
登録日2019-02-22
公開日2019-06-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019
5OBM
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BU of 5obm by Molmil
Crystal structure of Gentamicin bound to the yeast 80S ribosome
分子名称: (2R,3R,4R,5R)-2-((1S,2S,3R,4S,6R)-4,6-DIAMINO-3-((2R,3R,6S)-3-AMINO-6-(AMINOMETHYL)-TETRAHYDRO-2H-PYRAN-2-YLOXY)-2-HYDR OXYCYCLOHEXYLOXY)-5-METHYL-4-(METHYLAMINO)-TETRAHYDRO-2H-PYRAN-3,5-DIOL, 18S ribosomal RNA, 25S ribosomal RNA, ...
著者Prokhorova, I, Djumagulov, M, Urzhumtsev, A, Yusupov, M, Yusupova, G.
登録日2017-06-28
公開日2017-12-13
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Aminoglycoside interactions and impacts on the eukaryotic ribosome.
Proc. Natl. Acad. Sci. U.S.A., 114, 2017
6R87
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BU of 6r87 by Molmil
Yeast Vms1 (Q295L)-60S ribosomal subunit complex (pre-state without Arb1)
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Su, T, Izawa, T, Cheng, J, Yamashita, Y, Berninghausen, O, Inada, T, Neupert, W, Beckmann, R.
登録日2019-03-31
公開日2019-06-26
最終更新日2019-07-10
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
Nature, 570, 2019
5FCI
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BU of 5fci by Molmil
Structure of the vacant uL3 W255C mutant 80S yeast ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Mailliot, J, Garreau de Loubresse, N, Yusupova, G, Dinman, J.D, Yusupov, M.
登録日2015-12-15
公開日2016-05-11
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Crystal Structures of the uL3 Mutant Ribosome: Illustration of the Importance of Ribosomal Proteins for Translation Efficiency.
J.Mol.Biol., 428, 2016
6HD7
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BU of 6hd7 by Molmil
Cryo-EM structure of the ribosome-NatA complex
分子名称: 4-{(2R)-2-[(1S,3S,5S)-3,5-dimethyl-2-oxocyclohexyl]-2-hydroxyethyl}piperidine-2,6-dione, 5.8S rRNA, 5S rRNA, ...
著者Knorr, A.G, Becker, T, Beckmann, R.
登録日2018-08-17
公開日2018-12-19
最終更新日2019-01-16
実験手法ELECTRON MICROSCOPY (3.4 Å)
主引用文献Ribosome-NatA architecture reveals that rRNA expansion segments coordinate N-terminal acetylation.
Nat. Struct. Mol. Biol., 26, 2019
5APO
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BU of 5apo by Molmil
Structure of the yeast 60S ribosomal subunit in complex with Arx1, Alb1 and C-terminally tagged Rei1
分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ...
著者Greber, B.J, Gerhardy, S, Leitner, A, Leibundgut, M, Salem, M, Boehringer, D, Leulliot, N, Aebersold, R, Panse, V.G, Ban, N.
登録日2015-09-17
公開日2015-12-16
最終更新日2019-12-18
実験手法ELECTRON MICROSCOPY (3.41 Å)
主引用文献Insertion of the Biogenesis Factor Rei1 Probes the Ribosomal Tunnel during 60S Maturation.
Cell(Cambridge,Mass.), 164, 2016
4U56
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BU of 4u56 by Molmil
Crystal structure of Blasticidin S bound to the yeast 80S ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Garreau de Loubresse, N, Prokhorova, I, Yusupova, G, Yusupov, M.
登録日2014-07-24
公開日2014-10-22
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural basis for the inhibition of the eukaryotic ribosome.
Nature, 513, 2014
5DGE
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BU of 5dge by Molmil
Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Melnikov, S, Mailliot, J, Shin, B.-S, Rigger, L, Yusupova, G, Micura, R, Dever, T.E, Yusupov, M.
登録日2015-08-27
公開日2017-01-25
最終更新日2024-01-10
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Coping with proline stalling: structural basis of hypusine-induced protein synthesis by the eukaryotic ribosome
To Be Published
7ZPQ
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BU of 7zpq by Molmil
Structure of the RQT-bound 80S ribosome from S. cerevisiae (C1)
分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ...
著者Best, K.M, Ikeuchi, K, Kater, L, Best, D.M, Musial, J, Matsuo, Y, Berninghausen, O, Becker, T, Inada, T, Beckmann, R.
登録日2022-04-28
公開日2023-02-22
最終更新日2023-03-01
実験手法ELECTRON MICROSCOPY (3.47 Å)
主引用文献Structural basis for clearing of ribosome collisions by the RQT complex.
Nat Commun, 14, 2023
6QTZ
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BU of 6qtz by Molmil
Cryo-EM structures of Lsg1-TAP pre-60S ribosomal particles
分子名称: 25S rRNA, 5.8S rRNA, 5S rRNA, ...
著者Kargas, V, Warren, A.J.
登録日2019-02-26
公開日2019-06-26
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.5 Å)
主引用文献Mechanism of completion of peptidyltransferase centre assembly in eukaryotes.
Elife, 8, 2019

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