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PDB: 306 件

6TQN
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BU of 6tqn by Molmil
rrn anti-termination complex without S4
分子名称: 30S ribosomal protein S10, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N.
登録日2019-12-17
公開日2020-08-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis.
Mol.Cell, 79, 2020
5NSR
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BU of 5nsr by Molmil
Cryo-EM structure of RNA polymerase-sigma54 holo enzyme with promoter DNA closed complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Glyde, R, Ye, F.Z, Darbari, V.C, Zhang, N, Buck, M, Zhang, X.D.
登録日2017-04-26
公開日2017-06-28
最終更新日2019-12-11
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structures of RNA Polymerase Closed and Intermediate Complexes Reveal Mechanisms of DNA Opening and Transcription Initiation.
Mol. Cell, 67, 2017
6XAS
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BU of 6xas by Molmil
CryoEM Structure of E. coli Rho-dependent Transcription Pre-termination Complex
分子名称: DNA (29-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Hao, Z.T, Kim, H.K, Walz, T, Nudler, E.
登録日2020-06-04
公開日2020-12-16
最終更新日2024-03-06
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Pre-termination Transcription Complex: Structure and Function.
Mol.Cell, 81, 2021
8G4W
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BU of 8g4w by Molmil
Cryo-EM consensus structure of Escherichia coli que-PEC (paused elongation complex) RNA Polymerase plus preQ1 ligand
分子名称: 7-DEAZA-7-AMINOMETHYL-GUANINE, DNA (31-MER), DNA (39-mer), ...
著者Porta, J.C, Chauvier, A, Deb, I, Ellinger, E, Frank, A.T, Meze, K, Ohi, M.D, Walter, N.G.
登録日2023-02-10
公開日2023-06-21
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis for control of bacterial RNA polymerase pausing by a riboswitch and its ligand.
Nat.Struct.Mol.Biol., 30, 2023
8UQP
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BU of 8uqp by Molmil
Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, mRNA with a 24 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
分子名称: 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ...
著者Molodtsov, V, Wang, C, Ebright, R.H.
登録日2023-10-24
公開日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Escherichia coli transcription-translation coupled complex class A (TTC-A) containing RfaH bound to ops signal, mRNA with a 21 nt long spacer, and fMet-tRNAs in E-site and P-site of the ribosome
Nat.Struct.Mol.Biol., 2024
8REE
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BU of 8ree by Molmil
Cryo-EM structure of bacterial RNA polymerase-sigma54 initial transcribing complex - 9nt complex
分子名称: DNA (45-MER), DNA (49-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Gao, F, Zhang, X.
登録日2023-12-10
公開日2024-01-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of sigma 54 displacement and promoter escape in bacterial transcription.
Proc.Natl.Acad.Sci.USA, 121, 2024
7PY3
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BU of 7py3 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusA (the consensus NusA-EC)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-08
公開日2022-03-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY8
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BU of 7py8 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (NusG-EC in less-swiveled conformation)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-09
公開日2022-03-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
7PY1
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BU of 7py1 by Molmil
CryoEM structure of E.coli RNA polymerase elongation complex bound to NusG (the consensus NusG-EC)
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Zhu, C, Guo, X, Weixlbaumer, A.
登録日2021-10-08
公開日2022-03-23
最終更新日2024-07-17
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Transcription factors modulate RNA polymerase conformational equilibrium.
Nat Commun, 13, 2022
6R9B
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BU of 6r9b by Molmil
Cryo-EM structure of bacterial RNAP with a DNA mimic protein Ocr from T7 phage
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Ye, F.Z, Zhang, X.D.
登録日2019-04-03
公開日2020-02-26
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of transcription inhibition by the DNA mimic protein Ocr of bacteriophage T7
Elife, 2020
6ASX
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BU of 6asx by Molmil
CryoEM structure of E.coli his pause elongation complex
分子名称: DNA (32-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Landick, R, Darst, S.A.
登録日2017-08-25
公開日2018-03-28
最終更新日2024-03-13
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献RNA Polymerase Accommodates a Pause RNA Hairpin by Global Conformational Rearrangements that Prolong Pausing.
Mol. Cell, 69, 2018
6P19
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BU of 6p19 by Molmil
Q21 transcription antitermination complex: loaded complex
分子名称: DNA (123-MER) fragment carrying phage-21 pR' promoter, pause element, and transcribed region, ...
著者Yin, Z, Ebright, R.H.
登録日2019-05-19
公開日2019-06-26
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural basis of Q-dependent antitermination.
Proc.Natl.Acad.Sci.USA, 116, 2019
6TQO
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BU of 6tqo by Molmil
rrn anti-termination complex
分子名称: 30S ribosomal protein S10, 30S ribosomal protein S4, DNA-directed RNA polymerase subunit alpha, ...
著者Huang, Y.H, Wahl, M.C, Loll, B, Hilal, T, Said, N.
登録日2019-12-17
公開日2020-08-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structure-Based Mechanisms of a Molecular RNA Polymerase/Chaperone Machine Required for Ribosome Biosynthesis.
Mol.Cell, 79, 2020
6KJ6
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BU of 6kj6 by Molmil
cryo-EM structure of Escherichia coli Crl transcription activation complex
分子名称: DNA (51-MER), DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Xu, J, Zhang, Y.
登録日2019-07-21
公開日2020-01-01
最終更新日2024-03-27
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Crl activates transcription by stabilizing active conformation of the master stress transcription initiation factor.
Elife, 8, 2019
7N4E
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BU of 7n4e by Molmil
Escherichia coli sigma 70-dependent paused transcription elongation complex
分子名称: 5'-R(*UP*UP*CP*GP*GP*AP*GP*AP*GP*GP*UP*A)-3', DNA (61-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Molodtsov, V, Su, M, Ebright, R.H.
登録日2021-06-04
公開日2022-06-15
最終更新日2024-05-29
実験手法ELECTRON MICROSCOPY (3.8 Å)
主引用文献Structural and mechanistic basis of sigma-dependent transcriptional pausing.
Proc.Natl.Acad.Sci.USA, 119, 2022
6UTZ
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BU of 6utz by Molmil
E. coli sigma-S transcription initiation complex with a 6-nt RNA ("Fresh" crystal soaked with CTP and UTP for 30 minutes)
分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.803 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6N62
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BU of 6n62 by Molmil
Escherichia coli RNA polymerase sigma70-holoenzyme bound to upstream fork promoter DNA
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Braffman, N, Hauver, J, Campbell, E.A, Darst, S.A.
登録日2018-11-24
公開日2019-01-09
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.803 Å)
主引用文献Structural mechanism of transcription inhibition by lasso peptides microcin J25 and capistruin.
Proc. Natl. Acad. Sci. U.S.A., 116, 2019
5W1S
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BU of 5w1s by Molmil
X-ray crystal structure of Escherichia coli RNA polymerase and TraR complex
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Murakami, K.S, Molodtsov, V.
登録日2017-06-04
公開日2017-06-14
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (3.805 Å)
主引用文献Allosteric Effector ppGpp Potentiates the Inhibition of Transcript Initiation by DksA.
Mol. Cell, 69, 2018
4KMU
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BU of 4kmu by Molmil
X-ray crystal structure of the Escherichia coli RNA polymerase in complex with Rifampin
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Murakami, K.S.
登録日2013-05-08
公開日2013-05-22
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (3.85 Å)
主引用文献X-ray Crystal Structures of the Escherichia coli RNA Polymerase in Complex with Benzoxazinorifamycins.
J.Med.Chem., 56, 2013
6UTW
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BU of 6utw by Molmil
E. coli sigma-S transcription initiation complex with a 4-nt RNA ("Fresh" crystal)
分子名称: DIPHOSPHATE, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Zuo, Y, De, S, Steitz, T.A.
登録日2019-10-30
公開日2020-08-26
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (3.854 Å)
主引用文献Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation.
Iscience, 23, 2020
6PMI
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BU of 6pmi by Molmil
Sigm28-transcription initiation complex with specific promoter at the state 1
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Liu, B, Shi, W.
登録日2019-07-02
公開日2020-05-13
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.86 Å)
主引用文献Structural basis of bacterial sigma28-mediated transcription reveals roles of the RNA polymerase zinc-binding domain.
Embo J., 39, 2020
5UAL
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BU of 5ual by Molmil
Escherichia coli RNA polymerase and Rifampin complex, RpoB S531L mutant
分子名称: DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, DNA-directed RNA polymerase subunit beta', ...
著者Molodtsov, V, Scharf, N.T, Stefan, M.A, Garcia, G.A, Murakami, K.S.
登録日2016-12-19
公開日2017-01-11
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (3.887 Å)
主引用文献Structural basis for rifamycin resistance of bacterial RNA polymerase by the three most clinically important RpoB mutations found in Mycobacterium tuberculosis.
Mol. Microbiol., 103, 2017
8EH9
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BU of 8eh9 by Molmil
Cryo-EM structure of his-elemental paused elongation complex with a folded TL and a rotated RH-FL (2)
分子名称: CHAPSO, DNA-directed RNA polymerase subunit alpha, DNA-directed RNA polymerase subunit beta, ...
著者Kang, J.Y, Chen, J, Llewellyn, E, Landick, R, Darst, S.A.
登録日2022-09-13
公開日2023-03-01
最終更新日2024-06-19
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献An ensemble of interconverting conformations of the elemental paused transcription complex creates regulatory options.
Proc.Natl.Acad.Sci.USA, 120, 2023
6X2N
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BU of 6x2n by Molmil
Mfd-bound E.coli RNA polymerase elongation complex - I state
分子名称: ADENOSINE-5'-TRIPHOSPHATE, DNA (64-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Llewellyn, E, Chen, J, Kang, J.Y, Darst, S.A.
登録日2020-05-20
公開日2021-02-03
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Structural basis for transcription complex disruption by the Mfd translocase.
Elife, 10, 2021
6PSU
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BU of 6psu by Molmil
Escherichia coli RNA polymerase promoter unwinding intermediate (TRPi2) with TraR and rpsT P2 promoter
分子名称: CHAPSO, DNA (85-MER), DNA-directed RNA polymerase subunit alpha, ...
著者Chen, J, Chiu, C.E, Campbell, E.A, Darst, S.A.
登録日2019-07-13
公開日2020-03-25
最終更新日2024-03-20
実験手法ELECTRON MICROSCOPY (3.9 Å)
主引用文献Stepwise Promoter Melting by Bacterial RNA Polymerase.
Mol.Cell, 78, 2020

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件を2024-08-07に公開中

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