5IQR
| Structure of RelA bound to the 70S ribosome | 分子名称: | 30S ribosomal protein S10, 30S ribosomal protein S11, 30S ribosomal protein S12, ... | 著者 | Brown, A, Fernandez, I.S, Gordiyenko, Y, Ramakrishnan, V. | 登録日 | 2016-03-11 | 公開日 | 2016-05-04 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3 Å) | 主引用文献 | Ribosome-dependent activation of stringent control. Nature, 534, 2016
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5H5U
| Mechanistic insights into the alternative translation termination by ArfA and RF2 | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Ma, C, Kurita, D, Li, N, Chen, Y, Himeno, H, Gao, N. | 登録日 | 2016-11-09 | 公開日 | 2017-01-25 | 最終更新日 | 2024-10-09 | 実験手法 | ELECTRON MICROSCOPY (3.01 Å) | 主引用文献 | Mechanistic insights into the alternative translation termination by ArfA and RF2 Nature, 541, 2017
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5JC9
| Structure of the Escherichia coli ribosome with the U1052G mutation in the 16S rRNA | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Cocozaki, A, Ferguson, A. | 登録日 | 2016-04-14 | 公開日 | 2016-07-06 | 最終更新日 | 2016-08-03 | 実験手法 | X-RAY DIFFRACTION (3.03 Å) | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
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5MDW
| Structure of ArfA(A18T) and RF2 bound to the 70S ribosome (pre-accommodated state) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. | 登録日 | 2016-11-13 | 公開日 | 2016-12-14 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.06 Å) | 主引用文献 | Translational termination without a stop codon. Science, 354, 2016
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4WF1
| Crystal structure of the E. coli ribosome bound to negamycin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Olivier, N.B, Altman, R.B, Noeske, J, Basarab, G.S, Code, E, Ferguson, A.D, Gao, N, Huang, J, Juette, M.F, Livchak, S, Miller, M.D, Prince, D.B, Cate, J.H.D, Buurman, E.T, Blanchard, S.C. | 登録日 | 2014-09-11 | 公開日 | 2014-11-05 | 最終更新日 | 2024-10-16 | 実験手法 | X-RAY DIFFRACTION (3.09 Å) | 主引用文献 | Negamycin induces translational stalling and miscoding by binding to the small subunit head domain of the Escherichia coli ribosome. Proc.Natl.Acad.Sci.USA, 111, 2014
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8PKL
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4WWW
| Crystal structure of the E. coli ribosome bound to CEM-101 | 分子名称: | (3aS,4R,7S,9R,10R,11R,13R,15R,15aR)-1-{4-[4-(3-aminophenyl)-1H-1,2,3-triazol-1-yl]butyl}-4-ethyl-7-fluoro-11-methoxy-3a ,7,9,11,13,15-hexamethyl-2,6,8,14-tetraoxotetradecahydro-2H-oxacyclotetradecino[4,3-d][1,3]oxazol-10-yl 3,4,6-trideoxy-3-(dimethylamino)-beta-D-xylo-hexopyranoside, 16S rRNA, 23S rRNA, ... | 著者 | Dunkle, J.A, Zhang, W, Cate, J.H.D, Mankin, A.S. | 登録日 | 2014-11-12 | 公開日 | 2014-12-24 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Binding and action of CEM-101, a new fluoroketolide antibiotic that inhibits protein synthesis. Antimicrob. Agents Chemother., 54, 2010
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4V7U
| Crystal structure of the E. coli ribosome bound to erythromycin. | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Dunkle, J.A, Xiong, L, Mankin, A.S, Cate, J.H.D. | 登録日 | 2010-08-15 | 公開日 | 2014-07-09 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Structures of the Escherichia coli ribosome with antibiotics bound near the peptidyl transferase center explain spectra of drug action. Proc.Natl.Acad.Sci.USA, 107, 2010
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6WNT
| 50S ribosomal subunit without free 5S rRNA and perturbed PTC | 分子名称: | 23s-5s joint ribosomal RNA, 50S ribosomal protein L1, 50S ribosomal protein L10, ... | 著者 | Loveland, A.B, Korostelev, A.A, Mankin, A.S, Huang, S, Aleksashin, N.A, Klepacki, D, Reier, K, Kefi, A, Szal, A, Remme, J, Jaeger, L, Vazquez-Laslop, N. | 登録日 | 2020-04-23 | 公開日 | 2020-06-24 | 最終更新日 | 2024-03-06 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Ribosome engineering reveals the importance of 5S rRNA autonomy for ribosome assembly. Nat Commun, 11, 2020
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6S0K
| Ribosome nascent chain in complex with SecA | 分子名称: | 23S ribosomal RNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Jomaa, A, Wang, S, Shan, S, Ban, N. | 登録日 | 2019-06-17 | 公開日 | 2019-10-09 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The molecular mechanism of cotranslational membrane protein recognition and targeting by SecA. Nat.Struct.Mol.Biol., 26, 2019
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6YSR
| Structure of the P+9 stalled ribosome complex | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Chan, K.-H, Petrychenko, V, Mueller, C, Maracci, C, Holtkamp, W, Wilson, D.N, Fischer, N, Rodnina, M.V. | 登録日 | 2020-04-23 | 公開日 | 2020-08-19 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Mechanism of ribosome rescue by alternative ribosome-rescue factor B. Nat Commun, 11, 2020
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6X7K
| Cryo-EM structure of an Escherichia coli coupled transcription-translation complex B3 (TTC-B3) containing an mRNA with a 24 nt long spacer, transcription factors NusA and NusG, and fMet-tRNAs at P-site and E-site | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S1, ... | 著者 | Molodtsov, V, Ebright, R.H, Wang, C, Su, M. | 登録日 | 2020-05-30 | 公開日 | 2020-09-02 | 最終更新日 | 2020-09-23 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of transcription-translation coupling. Science, 369, 2020
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8FZI
| Cryo-EM structure of an E. coli rotated ribosome bound with RF3-GDPCP and p/E-tRNAPhe (Composite state II-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZD
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with apoRF3, RF1, P- and E-site tRNAPhe (Composite state I-B) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-07-31 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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8FZG
| Cryo-EM structure of an E. coli non-rotated ribosome termination complex bound with RF3-GDPCP, RF1, P- and E-site tRNAPhe (Composite state II-A) | 分子名称: | 16S Ribosomal RNA, 23S Ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Rybak, M.Y, Li, L, Lin, J, Gagnon, M.G. | 登録日 | 2023-01-28 | 公開日 | 2024-07-17 | 最終更新日 | 2024-08-07 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | The ribosome termination complex remodels release factor RF3 and ejects GDP. Nat.Struct.Mol.Biol., 2024
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5WE4
| 70S ribosome-EF-Tu wt complex with GppNHp | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Fislage, M, Brown, Z, Frank, J. | 登録日 | 2017-07-07 | 公開日 | 2018-04-25 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Cryo-EM shows stages of initial codon selection on the ribosome by aa-tRNA in ternary complex with GTP and the GTPase-deficient EF-TuH84A. Nucleic Acids Res., 46, 2018
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7PJY
| Structure of the 70S-EF-G-GDP ribosome complex with tRNAs in chimeric state 1 (CHI1-EF-G-GDP) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | 登録日 | 2021-08-24 | 公開日 | 2021-10-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
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7PJV
| Structure of the 70S-EF-G-GDP-Pi ribosome complex with tRNAs in hybrid state 1 (H1-EF-G-GDP-Pi) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | Petrychenko, V, Peng, B.Z, Schwarzer, A.C, Peske, F, Rodnina, M.V, Fischer, N. | 登録日 | 2021-08-24 | 公開日 | 2021-10-20 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural mechanism of GTPase-powered ribosome-tRNA movement. Nat Commun, 12, 2021
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5J8A
| Structure of the E coli 70S ribosome with the U1052G mutation in 16S rRNA bound to tigecycline | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Cocozaki, A, Ferguson, A. | 登録日 | 2016-04-07 | 公開日 | 2016-07-06 | 最終更新日 | 2016-08-03 | 実験手法 | X-RAY DIFFRACTION (3.1 Å) | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
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5MDZ
| Structure of the 70S ribosome (empty A site) | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | 著者 | James, N.R, Brown, A, Gordiyenko, Y, Ramakrishnan, V. | 登録日 | 2016-11-13 | 公開日 | 2016-12-14 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Translational termination without a stop codon. Science, 354, 2016
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8G7Q
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8URY
| Escherichia coli transcription-translation coupled complex class B (TTC-B) containing RfaH bound to ops signal, NusA, mRNA with a 30 nt long spacer, and fMet-tRNA in E-site and P-site of the ribosome | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S11, ... | 著者 | Molodtsov, V, Wang, C, Ebright, R.H. | 登録日 | 2023-10-27 | 公開日 | 2024-06-12 | 最終更新日 | 2024-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.1 Å) | 主引用文献 | Structural basis of RfaH-mediated transcription-translation coupling. Nat.Struct.Mol.Biol., 2024
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5IT8
| High-resolution structure of the Escherichia coli ribosome | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 1,2-ETHANEDIOL, 1,4-DIAMINOBUTANE, ... | 著者 | Cocozaki, A, Ferguson, A. | 登録日 | 2016-03-16 | 公開日 | 2016-07-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (3.12 Å) | 主引用文献 | Resistance mutations generate divergent antibiotic susceptibility profiles against translation inhibitors. Proc.Natl.Acad.Sci.USA, 113, 2016
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7BV8
| Mature 50S ribosomal subunit from RrmJ knock out E.coli strain | 分子名称: | 23S rRNA, 50S ribosomal protein L10, 50S ribosomal protein L11, ... | 著者 | Wang, W, Li, W.Q, Ge, X.L, Yan, K.G, Mandava, C.S, Sanyal, S, Gao, N. | 登録日 | 2020-04-09 | 公開日 | 2020-07-01 | 最終更新日 | 2024-03-27 | 実験手法 | ELECTRON MICROSCOPY (3.14 Å) | 主引用文献 | Loss of a single methylation in 23S rRNA delays 50S assembly at multiple late stages and impairs translation initiation and elongation. Proc.Natl.Acad.Sci.USA, 117, 2020
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4V6C
| Crystal structure of the E. coli 70S ribosome in an intermediate state of ratcheting | 分子名称: | 16S rRNA, 23S rRNA, 30S ribosomal protein S10, ... | 著者 | Zhang, W, Dunkle, J.A, Cate, J.H.D. | 登録日 | 2009-06-27 | 公開日 | 2014-07-09 | 最終更新日 | 2014-12-10 | 実験手法 | X-RAY DIFFRACTION (3.19 Å) | 主引用文献 | Structures of the ribosome in intermediate States of ratcheting. Science, 325, 2009
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