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PDB: 34 件

1D3V
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CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH 2(S)-AMINO-6-BORONOHEXANOIC ACID, AN L-ARGININE ANALOG
分子名称: 2(S)-AMINO-6-BORONOHEXANOIC ACID, MANGANESE (II) ION, PROTEIN (ARGINASE)
著者Cox, J.D, Kim, N.N, Traish, A.M, Christianson, D.W.
登録日1999-10-01
公開日1999-11-17
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Arginase-boronic acid complex highlights a physiological role in erectile function.
Nat.Struct.Biol., 6, 1999
1ZPE
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Arginase I covalently modified with butylamine at Q19C
分子名称: Arginase 1, MANGANESE (II) ION
著者Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E.
登録日2005-05-16
公開日2005-12-06
最終更新日2023-11-15
実験手法X-RAY DIFFRACTION (1.7 Å)
主引用文献Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
1ZPG
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Arginase I covalently modified with propylamine at Q19C
分子名称: Arginase 1, MANGANESE (II) ION
著者Colleluori, D.M, Reczkowski, R.S, Emig, F.A, Cama, E, Cox, J.D, Scolnick, L.R, Compher, K, Jude, K, Han, S, Viola, R.E, Christianson, D.W, Ash, D.E.
登録日2005-05-16
公開日2005-12-06
最終更新日2021-10-20
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
3E8Z
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X-ray structure of rat arginase I-N130A mutant: the unliganded complex
分子名称: Arginase-1, MANGANESE (II) ION
著者Shishova, E.Y, Di Costanzo, L, Christianson, D.W.
登録日2008-08-20
公開日2008-12-02
最終更新日2023-11-29
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
1HQG
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CRYSTAL STRUCTURE OF THE H141C ARGINASE VARIANT COMPLEXED WITH PRODUCTS ORNITHINE AND UREA
分子名称: ARGINASE 1, L-ornithine, MANGANESE (II) ION, ...
著者Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W.
登録日2000-12-16
公開日2001-04-04
最終更新日2011-07-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Biochemistry, 40, 2001
1RLA
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THREE-DIMENSIONAL STRUCTURE OF RAT LIVER ARGINASE, THE BINUCLEAR MANGANESE METALLOENZYME OF THE UREA CYCLE
分子名称: ARGINASE, MANGANESE (II) ION
著者Kanyo, Z, Scolnick, L, Ash, D, Christianson, D.W.
登録日1996-08-15
公開日1997-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure of a unique binuclear manganese cluster in arginase.
Nature, 383, 1996
3E9B
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X-ray structure of rat arginase I-T135A mutant: the complex with BEC
分子名称: Arginase-1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Shishova, E.Y, Di Costanzo, L, Christianson, D.W.
登録日2008-08-21
公開日2008-12-02
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Probing the specificity determinants of amino acid recognition by arginase.
Biochemistry, 48, 2009
1T4T
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arginase-dinor-NOHA complex
分子名称: 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}ALANINE, Arginase 1, MANGANESE (II) ION
著者Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W.
登録日2004-04-30
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
1T5F
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arginase I-AOH complex
分子名称: (S)-2-AMINO-7,7-DIHYDROXYHEPTANOIC ACID, Arginase 1, MANGANESE (II) ION
著者Shin, H, Cama, E, Christianson, D.W.
登録日2004-05-04
公開日2005-05-17
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Design of amino acid aldehydes as transition-state analogue inhibitors of arginase
J.Am.Chem.Soc., 126, 2004
1HQ5
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CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH S-(2-BORONOETHYL)-L-CYSTEINE, AN L-ARGININE ANALOGUE
分子名称: ARGINASE 1, MANGANESE (II) ION, S-2-(BORONOETHYL)-L-CYSTEINE
著者Kim, N.N, Cox, J.D, Baggio, R.F, Emig, F.A, Mistry, S.K, Harper, S.L, Speicher, D.W, Morris Jr, S.M, Ash, D.E, Traish, A, Christianson, D.W.
登録日2000-12-14
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Probing erectile function: S-(2-boronoethyl)-L-cysteine binds to arginase as a transition state analogue and enhances smooth muscle relaxation in human penile corpus cavernosum.
Biochemistry, 40, 2001
1T5G
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Arginase-F2-L-Arginine complex
分子名称: ARGININE, Arginase 1, FLUORIDE ION, ...
著者Cama, E, Pethe, S, Boucher, J.-L, Han, S, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W.
登録日2004-05-04
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
1P8P
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, MANGANESE (II) ION
著者Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003
1TA1
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H141C mutant of rat liver arginase I
分子名称: Arginase 1, GLYCEROL, MANGANESE (II) ION
著者Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W.
登録日2004-05-19
公開日2005-08-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
1P8R
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, CHLORIDE ION, MANGANESE (II) ION, ...
著者Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003
3RLA
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ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
分子名称: ARGINASE, MANGANESE (II) ION
著者Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
登録日1997-05-07
公開日1998-05-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.54 Å)
主引用文献Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997
1T4P
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Arginase-dehydro-ABH complex
分子名称: Arginase 1, MANGANESE (II) ION, [(1E,5S)-5-AMINO-5-CARBOXYPENT-1-ENYL](TRIHYDROXY)BORATE(1-)
著者Cama, E, Pethe, S, Boucher, J.-L, Han, S, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W.
登録日2004-04-30
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
1T4R
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arginase-descarboxy-nor-NOHA complex
分子名称: 3-{[(E)-AMINO(HYDROXYIMINO)METHYL]AMINO}PROPAN-1-AMINIUM, Arginase 1, MANGANESE (II) ION
著者Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W.
登録日2004-04-30
公開日2005-04-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.6 Å)
主引用文献Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
1TBH
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H141D mutant of rat liver arginase I
分子名称: Arginase 1, MANGANESE (II) ION
著者Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W.
登録日2004-05-20
公開日2005-08-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
5RLA
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ALTERING THE BINUCLEAR MANGANESE CLUSTER OF ARGINASE DIMINISHES THERMOSTABILITY AND CATALYTIC FUNCTION
分子名称: ARGINASE, MANGANESE (II) ION
著者Scolnick, L.R, Kanyo, Z.F, Christianson, D.W.
登録日1997-05-07
公開日1998-05-13
最終更新日2024-04-03
実験手法X-RAY DIFFRACTION (2.74 Å)
主引用文献Altering the binuclear manganese cluster of arginase diminishes thermostability and catalytic function.
Biochemistry, 36, 1997
1HQH
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CRYSTAL STRUCTURE OF THE BINUCLEAR MANGANESE METALLOENZYME ARGINASE COMPLEXED WITH NOR-N-HYDROXY-L-ARGININE
分子名称: ARGINASE 1, MANGANESE (II) ION, NOR-N-OMEGA-HYDROXY-L-ARGININE
著者Cox, J.D, Cama, E, Colleluori, D.M, Ash, D.E, Christianson, D.W.
登録日2000-12-16
公開日2001-04-04
最終更新日2024-02-07
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Mechanistic and metabolic inferences from the binding of substrate analogues and products to arginase.
Biochemistry, 40, 2001
1T4S
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arginase-L-valine complex
分子名称: Arginase 1, MANGANESE (II) ION, VALINE
著者Cama, E, Pethe, S, Boucher, J.-L, Shoufa, H, Emig, F.A, Ash, D.E, Viola, R.E, Mansuy, D, Christianson, D.W.
登録日2004-04-30
公開日2004-10-12
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Inhibitor coordination interactions in the binuclear manganese cluster of arginase
Biochemistry, 43, 2004
1R1O
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Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase
分子名称: Arginase 1, MANGANESE (II) ION, S-[2-(AMINOSULFONYL)ETHYL]-D-CYSTEINE
著者Cama, E, Shin, H, Christianson, D.W.
登録日2003-09-24
公開日2003-10-28
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Design of Amino Acid Sulfonamides as Transition-State Analogue Inhibitors of Arginase
J.Am.Chem.Soc., 125, 2003
1TBJ
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H141A mutant of rat liver arginase I
分子名称: Arginase 1, GLYCEROL, MANGANESE (II) ION
著者Cama, E, Cox, J.D, Ash, D.E, Christianson, D.W.
登録日2004-05-20
公開日2005-08-16
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Probing the role of the hyper-reactive histidine residue of arginase.
Arch.Biochem.Biophys., 444, 2005
1P8M
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, MANGANESE (II) ION
著者Cama, E, Emig, F.A, Ash, E.-D, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.84 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I.
Biochemistry, 42, 2003
1P8N
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Structural and Functional Importance of First-Shell Metal Ligands in the Binuclear Manganese Cluster of Arginase I.
分子名称: Arginase 1, GLYCEROL, MANGANESE (II) ION
著者Cama, E, Emig, F.A, Ash, D.E, Christianson, D.W.
登録日2003-05-07
公開日2003-06-17
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Structural and functional importance of first-shell metal ligands in the binuclear manganese cluster of arginase I
Biochemistry, 42, 2003

 

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