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PDB: 96 件
3FJ8
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Crystal structure of C117I mutant of Human acidic fibroblast growth factor
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
4XKI
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Human Fibroblast Growth Factor - 1 (FGF-1) mutant S116R
分子名称: Fibroblast growth factor 1, GLYCEROL, NONAETHYLENE GLYCOL, ...
著者Xia, X.
登録日2015-01-12
公開日2016-01-20
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Biophysical characterizations of Fibroblast Growth Factor - 1 mutant with increased heparin binding affinity
To Be Published
1PZZ
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Crystal structure of FGF-1, V51N mutant
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Kim, J, Blaber, M.
登録日2003-07-14
公開日2004-07-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
3BAD
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Crystal structure of D70A/H93G mutant of Human acidic fibroblast growth factor
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2007-11-07
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
1K5U
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BU of 1k5u by Molmil
Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with His93 replaced by Gly (H93G).
分子名称: Acidic fibroblast growth factor, SULFATE ION
著者Kim, J, Blaber, S.I, Blaber, M.
登録日2001-10-12
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
3FJC
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BU of 3fjc by Molmil
Crystal structure of L44W mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
1HKN
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BU of 1hkn by Molmil
A complex between acidic fibroblast growth factor and 5-amino-2-naphthalenesulfonate
分子名称: 5-AMINO-NAPHTALENE-2-MONOSULFONATE, HEPARIN-BINDING GROWTH FACTOR 1
著者Fernandez-Tornero, C, Lozano, R.M, Gimenez-Gallego, G, Romero, A.
登録日2003-03-10
公開日2004-03-11
最終更新日2023-12-13
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Leads for Development of New Naphthalenesulfonate Derivatives with Enhanced Antiangiogenic Activity: Crystal Structure of Acidic Fibroblast Growth Factor in Complex with 5-Amino-2-Naphthalenesulfonate
J.Biol.Chem., 278, 2003
2AFG
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BU of 2afg by Molmil
2.0 ANGSTROM X-RAY STRUCTURE OF HUMAN ACIDIC FIBROBLAST GROWTH FACTOR
分子名称: ACIDIC FIBROBLAST GROWTH FACTOR, SULFATE ION
著者Blaber, M, Disalvo, J, Thomas, K.A.
登録日1995-07-21
公開日1995-10-15
最終更新日2024-02-14
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献X-ray crystal structure of human acidic fibroblast growth factor.
Biochemistry, 35, 1996
4QO3
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Crystal structure of C16S/N18S/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE
著者Blaber, M, Xia, X.
登録日2014-06-19
公開日2015-05-06
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.047 Å)
主引用文献Thermodynamics of Cysteine Substitution Suggest Unique Structural Role for Cysteine in Proteins
To be Published
1Q03
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Crystal structure of FGF-1, S50G/V51G mutant
分子名称: Heparin-binding growth factor 1
著者Kim, J, Blaber, M.
登録日2003-07-15
公開日2004-07-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.05 Å)
主引用文献Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
1K5V
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Human acidic fibroblast growth factor. 141 amino acid form with amino terminal His tag with Asn106 replaced by Gly (N106G).
分子名称: Acidic fibroblast growth factor, SULFATE ION
著者Kim, J, Blaber, S.I, Blaber, M.
登録日2001-10-12
公開日2002-02-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Alternative type I and I' turn conformations in the beta8/beta9 beta-hairpin of human acidic fibroblast growth factor.
Protein Sci., 11, 2002
3CRI
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BU of 3cri by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser, Glu82Asn and Lys101Ala
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3FJE
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BU of 3fje by Molmil
Crystal structure of C83S mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
1YTO
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BU of 1yto by Molmil
Crystal Structure of Gly19 deletion Mutant of Human Acidic Fibroblast Growth Factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2005-02-10
公開日2006-01-24
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
3OJM
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BU of 3ojm by Molmil
Crystal Structure of FGF1 complexed with the ectodomain of FGFR2b harboring P253R Apert mutation
分子名称: Fibroblast growth factor receptor 2, Heparin-binding growth factor 1, SULFATE ION
著者Beenken, A, Mohammadi, M.
登録日2010-08-23
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1.
J.Biol.Chem., 287, 2012
3FJK
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BU of 3fjk by Molmil
Crystal structure of A66C mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3CRH
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BU of 3crh by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ser and Lys101Ala
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.15 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3OJ2
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BU of 3oj2 by Molmil
Crystal structure of FGF1 complexed with the ectodomain of FGFR2b harboring the A172F Pfeiffer syndrome mutation
分子名称: Fibroblast growth factor receptor 2, Heparin-binding growth factor 1, SULFATE ION
著者Beenken, A, Mohammadi, M.
登録日2010-08-20
公開日2011-08-31
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Plasticity in Interactions of Fibroblast Growth Factor 1 (FGF1) N Terminus with FGF Receptors Underlies Promiscuity of FGF1.
J.Biol.Chem., 287, 2012
3JUT
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BU of 3jut by Molmil
Acidic Fibroblast Growth Factor (FGF-1) complexed with gentisic acid
分子名称: 2,5-dihydroxybenzoic acid, Heparin-binding growth factor 1
著者Fernandez, I.S, Gimenez-Gallego, G, Romero, A.
登録日2009-09-15
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.25 Å)
主引用文献Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
J.Biol.Chem., 285, 2010
3HOM
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BU of 3hom by Molmil
Crystal structure of oxidized A66C mutant of Human acidic fibroblast growth factor
分子名称: Acidic fibroblast growth factor, FORMIC ACID, SULFATE ION
著者Blaber, M, Lee, J.
登録日2009-06-02
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3UD9
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BU of 3ud9 by Molmil
Crystal Structure Analysis of FGF1-Disaccharide(NI23) complex
分子名称: 2-deoxy-6-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION
著者Hung, S.-C, Shi, Z.
登録日2011-10-27
公開日2012-11-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.34 Å)
主引用文献Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction
J.Am.Chem.Soc., 134, 2012
3UD8
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Crystal Structure Analysis of FGF1-Disaccharide(NI22) complex
分子名称: 2-deoxy-3-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION
著者Hung, S.-C, Shi, Z.
登録日2011-10-27
公開日2012-11-28
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (2.37 Å)
主引用文献Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction
J.Am.Chem.Soc., 134, 2012
1DJS
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BU of 1djs by Molmil
LIGAND-BINDING PORTION OF FIBROBLAST GROWTH FACTOR RECEPTOR 2 IN COMPLEX WITH FGF1
分子名称: PROTEIN (FIBROBLAST GROWTH FACTOR 1), PROTEIN (FIBROBLAST GROWTH FACTOR RECEPTOR 2), SULFATE ION
著者Stauber, D.J, Digabriele, A.D, Hendrickson, W.A.
登録日1999-12-03
公開日2000-01-12
最終更新日2022-12-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Structural interactions of fibroblast growth factor receptor with its ligands.
Proc.Natl.Acad.Sci.USA, 97, 2000
3UDA
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BU of 3uda by Molmil
Crystal Structure Analysis of FGF1-Disaccharide(NI24) complex
分子名称: 2-deoxy-3,6-di-O-sulfo-2-(sulfoamino)-alpha-D-glucopyranose-(1-4)-1-O-methyl-2-O-sulfo-alpha-L-idopyranuronic acid, Heparin-binding growth factor 1, PHOSPHATE ION
著者Hung, S.-C, Shi, Z.
登録日2011-10-27
公開日2012-11-28
最終更新日2024-03-20
実験手法X-RAY DIFFRACTION (2.51 Å)
主引用文献Divergent synthesis of 48 heparan sulfate-based disaccharides and probing the specific sugar-fibroblast growth factor-1 interaction
J.Am.Chem.Soc., 134, 2012
2NTD
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Human fibroblast growth factor-1 (140 amino acid form) with Cys117Val/Pro134Cys mutations
分子名称: Acidic fibroblast growth factor 1, FORMIC ACID
著者Dubey, V.K, Blaber, M.
登録日2006-11-07
公開日2007-07-24
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.52 Å)
主引用文献Spackling the Crack: Stabilizing Human Fibroblast Growth Factor-1 by Targeting the N and C terminus beta-Strand Interactions
J.Mol.Biol., 371, 2007

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