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PDB: 96 件
3BAG
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Crystal structure of K112N/N114A mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Lee, J, Blaber, M.
登録日2007-11-07
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3BA5
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BU of 3ba5 by Molmil
Crystal structure of D28A mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2007-11-07
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.75 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
1JT4
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BU of 1jt4 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND VAL 109 REPLACED BY LEU (V109L)
分子名称: FORMIC ACID, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.78 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
4Q91
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BU of 4q91 by Molmil
Crystal structure of C16A/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
分子名称: FORMIC ACID, Fibroblast growth factor 1, PHOSPHATE ION
著者Xia, X, Blaber, M.
登録日2014-04-28
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.799 Å)
主引用文献Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
4Q9P
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BU of 4q9p by Molmil
Crystal structure of C16T/K12V/C117V/P134V mutant of human acidic fibroblast growth factor
分子名称: Fibroblast growth factor 1
著者Blaber, M, Xia, X.
登録日2014-05-01
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Mutation choice to eliminate buried free cysteines in protein therapeutics.
J.Pharm.Sci., 104, 2015
3BAQ
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BU of 3baq by Molmil
Crystal structure of L26A mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2007-11-08
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
1Q04
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BU of 1q04 by Molmil
Crystal structure of FGF-1, S50E/V51N
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Kim, J, Blaber, M.
登録日2003-07-15
公開日2004-07-27
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Sequence swapping does not result in conformation swapping for the beta4/beta5 and beta8/beta9 beta-hairpin turns in human acidic fibroblast growth factor
Protein Sci., 14, 2005
3BA4
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BU of 3ba4 by Molmil
Crystal structure of L26D mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2007-11-07
公開日2008-04-15
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献A logical OR redundancy within the Asx-Pro-Asx-Gly type I beta-turn motif.
J.Mol.Biol., 377, 2008
3CQA
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BU of 3cqa by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala and Lys101Ala
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-02
公開日2009-04-07
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (1.8 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
1JT5
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Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Terminal His Tag AND LEU 73 REPLACED BY VAL AND VAL 109 REPLACED BY LEU (L73V/V109L)
分子名称: SULFATE ION, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
2AQZ
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Crystal structure of FGF-1, S17T/N18T/G19 deletion mutant
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2005-08-18
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
3CRG
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BU of 3crg by Molmil
Crystal structure of human fibroblast growth factor-1 with mutations Glu81Ala, Glu82Asn and Lys101Ala
分子名称: FORMIC ACID, GLYCEROL, Heparin-binding growth factor 1, ...
著者Meher, A.K, Honjo, E, Kuroki, R, Lee, J, Somasundaram, T, Blaber, M.
登録日2008-04-07
公開日2009-02-17
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (1.85 Å)
主引用文献Engineering an improved crystal contact across a solvent-mediated interface of human fibroblast growth factor 1.
Acta Crystallogr.,Sect.F, 65, 2009
3FJ9
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BU of 3fj9 by Molmil
Crystal structure of F85W mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
1Z2V
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BU of 1z2v by Molmil
Crystal Structure of Glu60 deletion Mutant of Human Acidic Fibroblast Growth Factor
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Lee, J, Blaber, M.
登録日2005-03-09
公開日2006-02-07
最終更新日2023-08-23
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Conversion of type I 4:6 to 3:5 beta-turn types in human acidic fibroblast growth factor: Effects upon structure, stability, folding, and mitogenic function.
Proteins, 62, 2006
3FJD
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BU of 3fjd by Molmil
Crystal structure of L44F/F132W mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3FJJ
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BU of 3fjj by Molmil
Crystal structure of C83V mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3FJH
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BU of 3fjh by Molmil
Crystal structure of C83A mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
3FJF
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BU of 3fjf by Molmil
Crystal structure of C83T mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Structural basis of conserved cysteine in the fibroblast growth factor family: evidence for a vestigial half-cystine.
J.Mol.Biol., 393, 2009
1JT3
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BU of 1jt3 by Molmil
Human Acidic Fibroblast Growth Factor. 141 Amino Acid Form with Amino Histidine Tag AND LEU 73 REPLACED BY VAL (L73V)
分子名称: SULFATE ION, acidic fibroblast growth factor
著者Brych, S.R, Blaber, S.I, Logan, T.M, Blaber, M.
登録日2001-08-20
公開日2001-12-19
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Structure and stability effects of mutations designed to increase the primary sequence symmetry within the core region of a beta-trefoil.
Protein Sci., 10, 2001
3FJA
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BU of 3fja by Molmil
Crystal structure of F132W mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
3FGM
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BU of 3fgm by Molmil
Crystal structure of L44F/C83T/C117V/F132W mutant of Human acidic fibroblast growth factor
分子名称: FORMIC ACID, Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-06
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009
1NZK
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BU of 1nzk by Molmil
Crystal Structure of a Multiple Mutant (L44F, L73V, V109L, L111I, C117V) of Human Acidic Fibroblast Growth Factor
分子名称: Acidic Fibroblast Growth Factor, FORMIC ACID, SULFATE ION
著者Brych, S.R, Kim, J, Logan, T.M, Blaber, M.
登録日2003-02-18
公開日2004-03-02
最終更新日2023-08-16
実験手法X-RAY DIFFRACTION (1.95 Å)
主引用文献Accommodation of a highly symmetric core within a symmetric protein superfold.
Protein Sci., 12, 2003
4YOL
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BU of 4yol by Molmil
Human fibroblast growth factor-1 C16S/A66C/C117A/P134A
分子名称: CITRATE ANION, Fibroblast growth factor 1, IMIDAZOLE
著者Xia, X, Blaber, M.
登録日2015-03-11
公開日2016-03-16
最終更新日2019-02-13
実験手法X-RAY DIFFRACTION (1.97 Å)
主引用文献Engineering a Cysteine-Free Form of Human Fibroblast Growth Factor-1 for "Second Generation" Therapeutic Application.
J.Pharm.Sci., 105, 2016
3K1X
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BU of 3k1x by Molmil
Acidic Fibroblast Growth Factor (FGF-1) complexed with dobesilate
分子名称: 2,5-dihydroxybenzenesulfonic acid, Heparin-binding growth factor 1
著者Romero, A, Fernandez, I.S, Gimenez-Gallego, G.
登録日2009-09-29
公開日2010-02-02
最終更新日2023-11-01
実験手法X-RAY DIFFRACTION (1.98 Å)
主引用文献Gentisic acid, a compound associated with plant defense and a metabolite of aspirin, heads a new class of in vivo fibroblast growth factor inhibitors.
J.Biol.Chem., 285, 2010
3FJB
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Crystal structure of V31I mutant of Human acidic fibroblast growth factor
分子名称: Heparin-binding growth factor 1, SULFATE ION
著者Blaber, M, Lee, J.
登録日2008-12-14
公開日2009-10-06
最終更新日2023-09-06
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献The interaction between thermodynamic stability and buried free cysteines in regulating the functional half-life of fibroblast growth factor-1.
J.Mol.Biol., 393, 2009

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